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LM 't Hart
LM 't Hart
Leiden University Medical Center
E-mail confirmado em lumc.nl - Página inicial
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Rare and low-frequency coding variants alter human adult height
E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ...
Nature 542 (7640), 186-190, 2017
6342017
Mitochondrial diabetes: molecular mechanisms and clinical presentation
JA Maassen, LM ‘t Hart, E Van Essen, RJ Heine, G Nijpels, ...
Diabetes 53 (suppl_1), S103-S109, 2004
5372004
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
3982021
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
SA Schäfer, O Tschritter, F Machicao, C Thamer, N Stefan, B Gallwitz, ...
Diabetologia 50, 2443-2450, 2007
3912007
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
2902022
Association of a leucine (7)-to-proline (7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels
MK Karvonen, U Pesonen, M Koulu, L Niskanen, M Laakso, A Rissanen, ...
Nature medicine 4 (12), 1434-1437, 1998
2611998
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.
K Zhou, SW Yee, EL Seiser, N van Leeuwen, R Tavendale, AJ Bennett, ...
Nature genetics 48 (9), 1055-1059, 2016
1972016
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
A Albrechtsen, N Grarup, Y Li, T Sparsø, G Tian, H Cao, T Jiang, SY Kim, ...
Diabetologia 56, 298-310, 2013
1632013
Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic β-Cell …
AM Simonis-Bik, G Nijpels, TW van Haeften, JJ Houwing-Duistermaat, ...
Diabetes 59 (1), 293-301, 2010
1542010
Molecular mechanisms of mitochondrial diabetes (MIDD)
JA Maassen, GMC Janssen, LM Hart
Annals of medicine 37 (3), 213-221, 2005
1462005
A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts
N Van Leeuwen, G Nijpels, ML Becker, H Deshmukh, K Zhou, ...
Diabetologia 55, 1971-1977, 2012
1382012
Mutation in mitochondrial tRNA (Leu (UUR)) gene associated with progressive kidney disease.
JJ Jansen, JA Maassen, FJ van der Woude, HA Lemmink, ...
Journal of the American Society of Nephrology 8 (7), 1118-1124, 1997
1371997
Tumor necrosis factor‐α plays an important role in restenosis development
PS Monraats, NMM Pires, A Schepers, WRP Agema, LSM Boesten, ...
The FASEB Journal 19 (14), 1998-2004, 2005
1312005
Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels
KHJ Gaens, I Ferreira, CJH van der Kallen, MMJ van Greevenbroek, ...
The Journal of Clinical Endocrinology & Metabolism 94 (12), 5174-5180, 2009
1222009
Heteroplasmy levels of a mitochondrial gene mutation associated with diabetes mellitus decrease in leucocyte DNA upon aging
LM Hart, JJ Jansen, HHPJ Lemkes, P de Knijff, JA Maassen
Human mutation 7 (3), 193-197, 1996
1131996
Variants in pharmacokinetic transporters and glycemic response to metformin: a Metgen meta‐analysis
T Dujic, K Zhou, SW Yee, N van Leeuwen, CE de Keyser, M Javorský, ...
Clinical Pharmacology & Therapeutics 101 (6), 763-772, 2017
1112017
A genome-wide association study of IVGTT-based measures of first-phase insulin secretion refines the underlying physiology of type 2 diabetes variants
AR Wood, A Jonsson, AU Jackson, N Wang, N Van Leewen, ND Palmer, ...
Diabetes 66 (8), 2296-2309, 2017
1102017
Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk
E Reiling, E Van’t Riet, MJ Groenewoud, LMC Welschen, EC Van Hove, ...
Diabetologia 52, 1866-1870, 2009
1002009
Variants in the sulphonylurea receptor gene: Association of the exon 16–3t variant with Type II diabetes mellitus in Dutch Caucasians
LM ’t Hart, P de Knijff, JM Dekker, RP Stolk, G Nijpels, FEE Van der Does, ...
Diabetologia 42, 617-620, 1999
1001999
The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway
LM ‘t Hart, A Fritsche, G Nijpels, N van Leeuwen, LA Donnelly, JM Dekker, ...
Diabetes 62 (9), 3275-3281, 2013
972013
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