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Fiona Bailey
Fiona Bailey
Senior Scientist
E-mail confirmado em x-cellr8.com - Página inicial
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A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties
JM Murphy, Q Zhang, SN Young, ML Reese, FP Bailey, PA Eyers, ...
Biochemical Journal 457 (2), 323-334, 2014
2712014
The hVps34‐SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth
R Bago, E Sommer, P Castel, C Crafter, FP Bailey, N Shpiro, J Baselga, ...
The EMBO journal 35 (17), 1902-1922, 2016
1022016
The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner
FP Bailey, DP Byrne, K Oruganty, CE Eyers, CJ Novotny, KM Shokat, ...
Biochemical Journal 467 (1), 47-62, 2015
902015
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells
DM Foulkes, DP Byrne, W Yeung, S Shrestha, FP Bailey, S Ferries, ...
Sci. Signal. 11 (549), eaat7951, 2018
722018
Going for broke: targeting the human cancer pseudokinome
FP Bailey, DP Byrne, D McSkimming, N Kannan, PA Eyers
Biochemical Journal 465 (2), 195-211, 2015
342015
Tribbles pseudokinases: novel targets for chemical biology and drug discovery?
DM Foulkes, DP Byrne, FP Bailey, PA Eyers
Biochemical Society Transactions 43 (5), 1095-1103, 2015
272015
Adaptation of the human Cell Line Activation Test (h-CLAT) to Animal-Product-Free Conditions.
A Edwards, L Roscoe, C Longmore, F Bailey, B Sim, C Treasure
ALTEX, 2018
192018
The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles
FP Bailey, VI Andreev, PA Eyers
Methods in enzymology 548, 117-146, 2014
172014
Kinome‐wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics
FP Bailey, K Clarke, H Kalirai, J Kenyani, H Shahidipour, F Falciani, ...
Pigment cell & melanoma research 31 (2), 253-266, 2018
142018
Towards 20, 20-difluorinated bryostatin: synthesis and biological evaluation of difluorinated C17, C27-fragments
EJ Thomas, PR Mears, S Hoekman, C Rye, F Bailey, D Byrne, PA Eyers
Organic & Biomolecular Chemistry, 2019
102019
Repurposing covalent EGFR/HER2 inhibitors for on-target degradation of human Tribbles 2 (TRIB2) pseudokinase
DM Foulkes, DP Byrne, FP Bailey, S Ferries, C Eyers, K Keeshan, ...
bioRxiv, 305243, 2018
22018
2) Going for broke: targeting the human cancer pseudokinome
FP Bailey, DP Byrne, D McSkimming, N Kannan, PA Eyers
Biochemical Journal 466 (1), 201-201, 2015
12015
The response of uveal melanoma (UM) cells to Bromodomain and Extra Terminal (BET) inhibitors
FP Bailey, H Kalirai, H Shahidipour, K Clarke, SE Coupland, PA Eyers
Investigative Ophthalmology & Visual Science 58 (8), 566-566, 2017
2017
Biochemical Journal www. biochemj. org
JM MURPHY, Q ZHANG, SN YOUNG, ML REESE, FP BAILEY, ...
Biochem. J 457, 323-334, 2014
2014
Biochemical Analysis of Human Cancer-Associated Pseudokinases
F Bailey
University of Sheffield, 2014
2014
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