Alexandre Prat
Alexandre Prat
CHUM, CRCHUM, Université de Montréal, Faculté de Médecine
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Human TH 17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
H Kebir, K Kreymborg, I Ifergan, A Dodelet-Devillers, R Cayrol, M Bernard, ...
Nature medicine 13 (10), 1173-1175, 2007
The blood–brain barrier
R Daneman, A Prat
Cold Spring Harbor perspectives in biology 7 (1), a020412, 2015
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
JI Alvarez, A Dodelet-Devillers, H Kebir, I Ifergan, PJ Fabre, S Terouz, ...
Science 334 (6063), 1727-1731, 2011
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ...
Nature medicine 22 (6), 586-597, 2016
Preferential recruitment of interferon‐γ–expressing TH17 cells in multiple sclerosis
H Kebir, I Ifergan, JI Alvarez, M Bernard, J Poirier, N Arbour, P Duquette, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
Brain‐immune connection: immuno‐regulatory properties of CNS‐resident cells
B Becher, A Prat, JP Antel
Glia 29 (4), 293-304, 2000
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
R Cayrol, K Wosik, JL Berard, A Dodelet-Devillers, I Ifergan, H Kebir, ...
Nature immunology 9 (2), 137-145, 2008
Glial influence on the blood brain barrier
JI Alvarez, T Katayama, A Prat
Glia 61 (12), 1939-1958, 2013
Glial cell influence on the human blood‐brain barrier
A Prat, K Biernacki, K Wosik, JP Antel
Glia 36 (2), 145-155, 2001
How do immune cells overcome the blood–brain barrier in multiple sclerosis?
C Larochelle, JI Alvarez, A Prat
FEBS letters 585 (23), 3770-3780, 2011
Disruption of central nervous system barriers in multiple sclerosis
JI Alvarez, R Cayrol, A Prat
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (2), 252-264, 2011
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation
L Mayo, SA Trauger, M Blain, M Nadeau, B Patel, JI Alvarez, ...
Nature medicine 20 (10), 1147-1156, 2014
Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment
T Vincent, P Saikali, R Cayrol, AD Roth, A Bar-Or, A Prat, JP Antel
The Journal of Immunology 181 (8), 5730-5737, 2008
Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy
R Li, A Rezk, Y Miyazaki, E Hilgenberg, H Touil, P Shen, CS Moore, ...
Science translational medicine 7 (310), 310ra166-310ra166, 2015
Treatment optimization in MS: Canadian MS Working Group updated recommendations
MS Freedman, D Selchen, DL Arnold, A Prat, B Banwell, M Yeung, ...
Canadian Journal of Neurological Sciences 40 (3), 307-323, 2013
How do immune cells support and shape the brain in health, disease, and aging?
M Schwartz, J Kipnis, S Rivest, A Prat
Journal of Neuroscience 33 (45), 17587-17596, 2013
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
NM Hooper, NG Seidah, A Prat
Essays in biochemistry 38, 79-94, 2002
An updated histological classification system for multiple sclerosis lesions
T Kuhlmann, S Ludwin, A Prat, J Antel, W Brück, H Lassmann
Acta neuropathologica 133 (1), 13-24, 2017
Immunologic privilege in the central nervous system and the blood–brain barrier
LL Muldoon, JI Alvarez, DJ Begley, RJ Boado, GJ Del Zoppo, ND Doolittle, ...
Journal of Cerebral Blood Flow & Metabolism 33 (1), 13-21, 2013
Angiotensin II controls occludin function and is required for blood–brain barrier maintenance: relevance to multiple sclerosis
K Wosik, R Cayrol, A Dodelet-Devillers, F Berthelet, M Bernard, ...
Journal of Neuroscience 27 (34), 9032-9042, 2007
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