| Aprataxin, a novel protein that protects against genotoxic stress N Gueven, OJ Becherel, AW Kijas, P Chen, O Howe, JH Rudolph, R Gatti, ... Human molecular genetics 13 (10), 1081-1093, 2004 | 206 | 2004 |
| Copper (II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic … M O’Connor, A Kellett, M McCann, G Rosair, M McNamara, O Howe, ... Journal of medicinal chemistry 55 (5), 1957-1968, 2012 | 178 | 2012 |
| The antibacterial activity of metal complexes containing 1, 10-phenanthroline: potential as alternative therapeutics in the era of antibiotic resistance L Viganor, O Howe, P McCarron, M McCann, M Devereux Current topics in medicinal chemistry 17 (11), 1280-1302, 2017 | 138 | 2017 |
| Evaluation of the potential of Raman microspectroscopy for prediction of chemotherapeutic response to cisplatin in lung adenocarcinoma H Nawaz, F Bonnier, P Knief, O Howe, FM Lyng, AD Meade, HJ Byrne Analyst 135 (12), 3070-3076, 2010 | 136 | 2010 |
| Bis-phenanthroline copper (II) phthalate complexes are potent in vitro antitumour agents with ‘self-activating’metallo-nuclease and DNA binding properties A Kellett, M O'Connor, M McCann, M McNamara, P Lynch, G Rosair, ... Dalton transactions 40 (5), 1024-1027, 2011 | 113 | 2011 |
| Non-thermal atmospheric plasma induces ROS-independent cell death in U373MG glioma cells and augments the cytotoxicity of temozolomide GE Conway, A Casey, V Milosavljevic, Y Liu, O Howe, PJ Cullen, ... British journal of cancer 114 (4), 435-443, 2016 | 96 | 2016 |
| Water-soluble bis (1, 10-phenanthroline) octanedioate Cu 2+ and Mn2+ complexes with unprecedented nano and picomolar in vitro cytotoxicity: promising leads for chemotherapeutic … A Kellett, M O'Connor, M McCann, O Howe, A Casey, P McCarron, ... MedChemComm 2 (7), 579-584, 2011 | 92 | 2011 |
| Radical-induced DNA damage by cytotoxic square-planar copper (II) complexes incorporating o-phthalate and 1, 10-phenanthroline or 2, 2′-dipyridyl A Kellett, O Howe, M O'Connor, M McCann, BS Creaven, S McClean, ... Free Radical Biology and Medicine 53 (3), 564-576, 2012 | 90 | 2012 |
| Silver nanoparticles induce pro‐inflammatory gene expression and inflammasome activation in human monocytes A Murphy, A Casey, G Byrne, G Chambers, O Howe Journal of Applied Toxicology 36 (10), 1311-1320, 2016 | 77 | 2016 |
| Reactive oxygen species-induced release of signalling factors in irradiated cells triggers membrane signalling and calcium influx in bystander cells FM Lyng, OL Howe, B McClean International journal of radiation biology 87 (7), 683-695, 2011 | 76 | 2011 |
| Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect H Furlong, C Mothersill, FM Lyng, O Howe Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 741, 35-43, 2013 | 74 | 2013 |
| Regulating Bioactivity of Cu2+ Bis-1,10-phenanthroline Artificial Metallonucleases with Sterically Functionalized Pendant Carboxylates A Prisecaru, V McKee, O Howe, G Rochford, M McCann, J Colleran, ... Journal of Medicinal Chemistry 56 (21), 8599-8615, 2013 | 68 | 2013 |
| Quantitative reagent-free detection of fibrinogen levels in human blood plasma using Raman spectroscopy KWC Poon, FM Lyng, P Knief, O Howe, AD Meade, JF Curtin, HJ Byrne, ... Analyst 137 (8), 1807-1814, 2012 | 67 | 2012 |
| Water-soluble and photo-stable silver (I) dicarboxylate complexes containing 1, 10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA … L Thornton, V Dixit, LON Assad, TP Ribeiro, DD Queiroz, A Kellett, ... Journal of inorganic biochemistry 159, 120-132, 2016 | 65 | 2016 |
| Doxorubicin kinetics and effects on lung cancer cell lines using in vitro Raman micro‐spectroscopy: binding signatures, drug resistance and DNA repair Z Farhane, F Bonnier, O Howe, A Casey, HJ Byrne Journal of Biophotonics 11 (1), e201700060, 2018 | 60 | 2018 |
| Disarming Pseudomonas aeruginosa Virulence by the Inhibitory Action of 1,10-Phenanthroline-5,6-Dione-Based Compounds: Elastase B (LasB) as a … ACM Galdino, L Viganor, AA De Castro, EFF Da Cunha, TP Mello, ... Frontiers in Microbiology 10, 1701, 2019 | 57 | 2019 |
| Targeting the folate receptor: improving efficacy in inorganic medicinal chemistry PM Carron, A Crowley, D O'Shea, M McCann, O Howe, M Hunt, ... Current Medicinal Chemistry 25 (23), 2675-2708, 2018 | 54 | 2018 |
| [Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial … C Slator, N Barron, O Howe, A Kellett ACS Chemical Biology 11 (1), 159-171, 2016 | 47 | 2016 |
| Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial dysfunction S Gorman, M Tosetto, F Lyng, O Howe, K Sheahan, D O’Donoghue, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 669 (1 …, 2009 | 47 | 2009 |
| Vibrational spectroscopy in sensing radiobiological effects: analyses of targeted and non-targeted effects in human keratinocytes AD Meade, O Howe, V Unterreiner, GD Sockalingum, HJ Byrne, FM Lyng Faraday discussions 187, 213-234, 2016 | 46 | 2016 |
