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Qiong Lin
Qiong Lin
Bayer AG
E-mail confirmado em bayer.com
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Aging of blood can be tracked by DNA methylation changes at just three CpG sites
CI Weidner, Q Lin, CM Koch, L Eisele, F Beier, P Ziegler, DO Bauerschlag, ...
Genome biology 15, 1-12, 2014
8812014
Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation
A Reinisch, N Etchart, D Thomas, NA Hofmann, M Fruehwirth, S Sinha, ...
Blood, the Journal of the American Society of Hematology 125 (2), 249-260, 2015
2452015
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling
M Hohwieler, A Illing, PC Hermann, T Mayer, M Stockmann, L Perkhofer, ...
Gut 66 (3), 473-486, 2017
2182017
Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks
A Schellenberg, Q Lin, H Schüler, CM Koch, S Joussen, B Denecke, ...
Aging (Albany NY) 3 (9), 873, 2011
2072011
DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy
Q Lin, CI Weidner, IG Costa, RE Marioni, MRP Ferreira, IJ Deary, ...
Aging (Albany NY) 8 (2), 394, 2016
1792016
The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation
M Kalwa, S Hänzelmann, S Otto, CC Kuo, J Franzen, S Joussen, ...
Nucleic acids research 44 (22), 10631-10643, 2016
1572016
Pluripotent stem cells escape from senescence-associated DNA methylation changes
CM Koch, K Reck, K Shao, Q Lin, S Joussen, P Ziegler, G Walenda, ...
Genome research 23 (2), 248-259, 2013
1532013
Specific age-associated DNA methylation changes in human dermal fibroblasts
CM Koch, CV Suschek, Q Lin, S Bork, M Goergens, S Joussen, N Pallua, ...
PloS one 6 (2), e16679, 2011
1502011
Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition
R Russell, L Perkhofer, S Liebau, Q Lin, A Lechel, FM Feld, E Hessmann, ...
Nature communications 6 (1), 7677, 2015
1482015
Modulation of calcium-activated potassium channels induces cardiogenesis of pluripotent stem cells and enrichment of pacemaker-like cells
A Kleger, T Seufferlein, D Malan, M Tischendorf, A Storch, A Wolheim, ...
Circulation 122 (18), 1823-1836, 2010
1402010
Parthenogenetic stem cells for tissue-engineered heart repair
M Didié, P Christalla, M Rubart, V Muppala, S Döker, B Unsöld, ...
The Journal of clinical investigation 123 (3), 1285-1298, 2013
1272013
Epigenetic aging signatures are coherently modified in cancer
Q Lin, W Wagner
PLoS genetics 11 (6), e1005334, 2015
1192015
Monitoring of cellular senescence by DNA‐methylation at specific CpG sites
CM Koch, S Joussen, A Schellenberg, Q Lin, M Zenke, W Wagner
Aging cell 11 (2), 366-369, 2012
1142012
ATM deficiency generating genomic instability sensitizes pancreatic ductal adenocarcinoma cells to therapy-induced DNA damage
L Perkhofer, A Schmitt, MC Romero Carrasco, M Ihle, S Hampp, ...
Cancer research 77 (20), 5576-5590, 2017
1032017
Human adult germline stem cells in question
K Ko, MJ Araúzo-Bravo, N Tapia, J Kim, Q Lin, C Bernemann, DW Han, ...
Nature 465 (7301), E1-E1, 2010
1002010
TBX3 directs cell-fate decision toward mesendoderm
CE Weidgang, R Russell, PR Tata, SJ Kühl, A Illing, M Müller, Q Lin, ...
Stem cell reports 1 (3), 248-265, 2013
952013
Matrix elasticity, replicative senescence and DNA methylation patterns of mesenchymal stem cells
A Schellenberg, S Joussen, K Moser, N Hampe, N Hersch, H Hemeda, ...
Biomaterials 35 (24), 6351-6358, 2014
772014
Rat embryonic fibroblasts improve reprogramming of human keratinocytes into induced pluripotent stem cells
L Linta, M Stockmann, KN Kleinhans, A Böckers, A Storch, H Zaehres, ...
Stem cells and development 21 (6), 965-976, 2012
742012
Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia
E Jost, Q Lin, CI Weidner, S Wilop, M Hoffmann, T Walenda, ...
Leukemia 28 (6), 1227-1234, 2014
702014
The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation
X Ding, X Wang, S Sontag, J Qin, P Wanek, Q Lin, M Zenke
Stem cells and development 23 (9), 931-940, 2014
702014
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