Zach Charlop-Powers
Zach Charlop-Powers
Director of Bioinformatics, Lodo Therapeutics
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The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro
WG Shreffler, RR Castro, ZY Kucuk, Z Charlop-Powers, G Grishina, S Yoo, ...
The Journal of Immunology 177 (6), 3677-3685, 2006
Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens
BM Hover, SH Kim, M Katz, Z Charlop-Powers, JG Owen, MA Ternei, ...
Nature microbiology 3 (4), 415-422, 2018
Aquatic environmental DNA detects seasonal fish abundance and habitat preference in an urban estuary
MY Stoeckle, L Soboleva, Z Charlop-Powers
PloS one 12 (4), e0175186, 2017
Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products
JG Owen, BVB Reddy, MA Ternei, Z Charlop-Powers, PY Calle, JH Kim, ...
Proceedings of the National Academy of Sciences 110 (29), 11797-11802, 2013
Discovery of MRSA active antibiotics using primary sequence from the human microbiome
J Chu, X Vila-Farres, D Inoyama, M Ternei, LJ Cohen, EA Gordon, ...
Nature chemical biology 12 (12), 1004-1006, 2016
Global biogeographic sampling of bacterial secondary metabolism
Z Charlop-Powers, JG Owen, BVB Reddy, MA Ternei, DO Guimarães, ...
Elife 4, e05048, 2015
Chemical-biogeographic survey of secondary metabolism in soil
Z Charlop-Powers, JG Owen, BVB Reddy, MA Ternei, SF Brady
Proceedings of the National Academy of Sciences 111 (10), 3757-3762, 2014
Transcytosis of IgE–antigen complexes by CD23a in human intestinal epithelial cells and its role in food allergy
H Li, A Nowak–Wegrzyn, Z Charlop–Powers, W Shreffler, M Chehade, ...
Gastroenterology 131 (1), 47-58, 2006
Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors
JG Owen, Z Charlop-Powers, AG Smith, MA Ternei, PY Calle, BVB Reddy, ...
Proceedings of the National Academy of Sciences 112 (14), 4221-4226, 2015
Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters
D Montiel, HS Kang, FY Chang, Z Charlop-Powers, SF Brady
Proceedings of the National Academy of Sciences 112 (29), 8953-8958, 2015
Natural product biosynthetic gene diversity in geographically distinct soil microbiomes
BVB Reddy, D Kallifidas, JH Kim, Z Charlop-Powers, Z Feng, SF Brady
Applied and environmental microbiology 78 (10), 3744-3752, 2012
Metagenomic small molecule discovery methods
Z Charlop-Powers, A Milshteyn, SF Brady
Current opinion in microbiology 19, 70-75, 2014
Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2
Z Charlop-Powers, L Zeng, Q Zhang, MM Zhou
Cell research 20 (5), 529-538, 2010
eSNaPD: a versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes
BVB Reddy, A Milshteyn, Z Charlop-Powers, SF Brady
Chemistry & biology 21 (8), 1023-1033, 2014
Multiplexed CRISPR/Cas9-and TAR-mediated promoter engineering of natural product biosynthetic gene clusters in yeast
HS Kang, Z Charlop-Powers, SF Brady
ACS synthetic biology 5 (9), 1002-1010, 2016
Lack of association of HLA class II alleles with peanut allergy
WG Shreffler, Z Charlop-Powers, SH Sicherer
Annals of Allergy, Asthma & Immunology 96 (6), 865-869, 2006
Urban park soil microbiomes are a rich reservoir of natural product biosynthetic diversity
Z Charlop-Powers, CC Pregitzer, C Lemetre, MA Ternei, J Maniko, ...
Proceedings of the national academy of sciences 113 (51), 14811-14816, 2016
Bacterial natural product biosynthetic domain composition in soil correlates with changes in latitude on a continent-wide scale
C Lemetre, J Maniko, Z Charlop-Powers, B Sparrow, AJ Lowe, SF Brady
Proceedings of the National Academy of Sciences 114 (44), 11615-11620, 2017
Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of …
Z Charlop-Powers, JJ Banik, JG Owen, JW Craig, SF Brady
ACS chemical biology 8 (1), 138-143, 2013
Biotechnological potential of Actinobacteria from Canadian and Azorean volcanic caves
C Riquelme, MLE Dapkevicius, AZ Miller, Z Charlop-Powers, S Brady, ...
Applied microbiology and biotechnology 101 (2), 843-857, 2017
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