Zach Charlop-Powers
Zach Charlop-Powers
Director of Bioinformatics, Lodo Therapeutics
E-mail confirmado em lodotherapeutics.com
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The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro
WG Shreffler, RR Castro, ZY Kucuk, Z Charlop-Powers, G Grishina, S Yoo, ...
The Journal of Immunology 177 (6), 3677-3685, 2006
2872006
Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens
BM Hover, SH Kim, M Katz, Z Charlop-Powers, JG Owen, MA Ternei, ...
Nature microbiology 3 (4), 415-422, 2018
1872018
Aquatic environmental DNA detects seasonal fish abundance and habitat preference in an urban estuary
MY Stoeckle, L Soboleva, Z Charlop-Powers
PloS one 12 (4), e0175186, 2017
1102017
Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products
JG Owen, BVB Reddy, MA Ternei, Z Charlop-Powers, PY Calle, JH Kim, ...
Proceedings of the National Academy of Sciences 110 (29), 11797-11802, 2013
982013
Discovery of MRSA active antibiotics using primary sequence from the human microbiome
J Chu, X Vila-Farres, D Inoyama, M Ternei, LJ Cohen, EA Gordon, ...
Nature chemical biology 12 (12), 1004-1006, 2016
972016
Global biogeographic sampling of bacterial secondary metabolism
Z Charlop-Powers, JG Owen, BVB Reddy, MA Ternei, DO Guimarães, ...
Elife 4, e05048, 2015
972015
Chemical-biogeographic survey of secondary metabolism in soil
Z Charlop-Powers, JG Owen, BVB Reddy, MA Ternei, SF Brady
Proceedings of the National Academy of Sciences 111 (10), 3757-3762, 2014
942014
Transcytosis of IgE–antigen complexes by CD23a in human intestinal epithelial cells and its role in food allergy
H Li, A Nowak–Wegrzyn, Z Charlop–Powers, W Shreffler, M Chehade, ...
Gastroenterology 131 (1), 47-58, 2006
942006
Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors
JG Owen, Z Charlop-Powers, AG Smith, MA Ternei, PY Calle, BVB Reddy, ...
Proceedings of the National Academy of Sciences 112 (14), 4221-4226, 2015
812015
Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters
D Montiel, HS Kang, FY Chang, Z Charlop-Powers, SF Brady
Proceedings of the National Academy of Sciences 112 (29), 8953-8958, 2015
752015
Natural product biosynthetic gene diversity in geographically distinct soil microbiomes
BVB Reddy, D Kallifidas, JH Kim, Z Charlop-Powers, Z Feng, SF Brady
Applied and environmental microbiology 78 (10), 3744-3752, 2012
752012
Metagenomic small molecule discovery methods
Z Charlop-Powers, A Milshteyn, SF Brady
Current opinion in microbiology 19, 70-75, 2014
692014
Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2
Z Charlop-Powers, L Zeng, Q Zhang, MM Zhou
Cell research 20 (5), 529-538, 2010
652010
eSNaPD: a versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes
BVB Reddy, A Milshteyn, Z Charlop-Powers, SF Brady
Chemistry & biology 21 (8), 1023-1033, 2014
592014
Multiplexed CRISPR/Cas9-and TAR-mediated promoter engineering of natural product biosynthetic gene clusters in yeast
HS Kang, Z Charlop-Powers, SF Brady
ACS synthetic biology 5 (9), 1002-1010, 2016
522016
Lack of association of HLA class II alleles with peanut allergy
WG Shreffler, Z Charlop-Powers, SH Sicherer
Annals of Allergy, Asthma & Immunology 96 (6), 865-869, 2006
522006
Urban park soil microbiomes are a rich reservoir of natural product biosynthetic diversity
Z Charlop-Powers, CC Pregitzer, C Lemetre, MA Ternei, J Maniko, ...
Proceedings of the national academy of sciences 113 (51), 14811-14816, 2016
432016
Bacterial natural product biosynthetic domain composition in soil correlates with changes in latitude on a continent-wide scale
C Lemetre, J Maniko, Z Charlop-Powers, B Sparrow, AJ Lowe, SF Brady
Proceedings of the National Academy of Sciences 114 (44), 11615-11620, 2017
302017
Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of …
Z Charlop-Powers, JJ Banik, JG Owen, JW Craig, SF Brady
ACS chemical biology 8 (1), 138-143, 2013
242013
Biotechnological potential of Actinobacteria from Canadian and Azorean volcanic caves
C Riquelme, MLE Dapkevicius, AZ Miller, Z Charlop-Powers, S Brady, ...
Applied microbiology and biotechnology 101 (2), 843-857, 2017
162017
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