Christopher M Overall
Christopher M Overall
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Strategies for MMP inhibition in cancer: innovations for the post-trial era
CM Overall, C López-Otín
Nature Reviews Cancer 2 (9), 657-672, 2002
15722002
Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
CM Overall, O Kleifeld
Nature Reviews Cancer 6 (3), 227-239, 2006
13062006
Human and mouse proteases: a comparative genomic approach
XS Puente, LM Sánchez, CM Overall, C López-Otín
Nature Reviews Genetics 4 (7), 544-558, 2003
11142003
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
K Wolf, YI Wu, Y Liu, J Geiger, E Tam, C Overall, MS Stack, P Friedl
Nature cell biology 9 (8), 893-904, 2007
10692007
Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3
GA McQuibban, JH Gong, EM Tam, CAG McCulloch, I Clark-Lewis, ...
Science 289 (5482), 1202-1206, 2000
8852000
Protease degradomics: a new challenge for proteomics
C López-Otín, CM Overall
Nature reviews Molecular cell biology 3 (7), 509-519, 2002
8322002
Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-β
CM Overall, JL Wrana, J Sodek
Journal of Biological Chemistry 264 (3), 1860-1869, 1989
8041989
Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1
GA McQuibban, GS Butler, JH Gong, L Bendall, C Power, I Clark-Lewis, ...
Journal of Biological Chemistry 276 (47), 43503-43508, 2001
7262001
Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo
GA McQuibban, JH Gong, JP Wong, JL Wallace, I Clark-Lewis, ...
Blood, The Journal of the American Society of Hematology 100 (4), 1160-1167, 2002
6862002
Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics
D Rodríguez, CJ Morrison, CM Overall
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (1), 39-54, 2010
6052010
Molecular determinants of metalloproteinase substrate specificity
CM Overall
Molecular biotechnology 22 (1), 51-86, 2002
5982002
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ...
Cancer research 71 (9), 3364-3376, 2011
5932011
Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells
R Khokha, P Waterhouse, S Yagel, PK Lala, CM Overall, G Norton, ...
Science 243 (4893), 947-950, 1989
5761989
Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with …
CM Overall, JL Wrana, J Sodek
Journal of Biological Chemistry 266 (21), 14064-14071, 1991
5741991
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
M Balbín, A Fueyo, AM Tester, AM Pendás, AS Pitiot, A Astudillo, ...
Nature genetics 35 (3), 252-257, 2003
5612003
Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: a comparison of sites in edentulous and partially edentulous patients
P Apse, RP Ellen, CM Overall, GA Zarb
Journal of Periodontal Research 24 (2), 96-105, 1989
4561989
Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products
O Kleifeld, A Doucet, U Auf dem Keller, A Prudova, O Schilling, ...
Nature biotechnology 28 (3), 281-288, 2010
4472010
Towards third generation matrix metalloproteinase inhibitors for cancer therapy
CM Overall, O Kleifeld
British journal of cancer 94 (7), 941-946, 2006
3862006
Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites
O Schilling, CM Overall
Nature biotechnology 26 (6), 685-694, 2008
3842008
In search of partners: linking extracellular proteases to substrates
CM Overall, CP Blobel
Nature reviews Molecular cell biology 8 (3), 245-257, 2007
3512007
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