Update on melatonin receptors: IUPHAR Review 20 R Jockers, P Delagrange, ML Dubocovich, RP Markus, N Renault, ... British journal of pharmacology 173 (18), 2702-2725, 2016 | 403 | 2016 |
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Y Suofu, W Li, FG Jean-Alphonse, J Jia, NK Khattar, J Li, SV Baranov, ... Proceedings of the National Academy of Sciences 114 (38), E7997-E8006, 2017 | 399 | 2017 |
Melatonin receptors: molecular pharmacology and signalling in the context of system bias E Cecon, A Oishi, R Jockers British journal of pharmacology 175 (16), 3263-3280, 2018 | 227 | 2018 |
MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential DP Zlotos, R Jockers, E Cecon, S Rivara, PA Witt-Enderby Journal of medicinal chemistry 57 (8), 3161-3185, 2014 | 201 | 2014 |
NF-κB drives the synthesis of melatonin in RAW 264.7 macrophages by inducing the transcription of the arylalkylamine-N-acetyltransferase (AA-NAT) gene SM Muxel, MA Pires-Lapa, AWA Monteiro, E Cecon, EK Tamura, ... PLoS One 7 (12), e52010, 2012 | 181 | 2012 |
The immune-pineal axis: a shuttle between endocrine and paracrine melatonin sources RP Markus, ZS Ferreira, PACM Fernandes, E Cecon Neuroimmunomodulation 14 (3-4), 126-133, 2007 | 181 | 2007 |
Immune-pineal axis: nuclear factor κB (NF-κB) mediates the shift in the melatonin source from pinealocytes to immune competent cells RP Markus, E Cecon, MA Pires-Lapa International journal of molecular sciences 14 (6), 10979-10997, 2013 | 157 | 2013 |
Effect of TNF‐α on the melatonin synthetic pathway in the rat pineal gland: basis for a ‘feedback’ of the immune response on circadian timing PACM Fernandes, E Cecon, RP Markus, ZS Ferreira Journal of pineal research 41 (4), 344-350, 2006 | 145 | 2006 |
TLR4 and CD14 receptors expressed in rat pineal gland trigger NFKB pathway S Da Silveira Cruz‐Machado, CE Carvalho‐Sousa, EK Tamura, L Pinato, ... Journal of pineal research 49 (2), 183-192, 2010 | 141 | 2010 |
Melatonin inhibits LPS‐induced NO production in rat endothelial cells EK Tamura, E Cecon, AWA Monteiro, CLM Silva, RP Markus Journal of pineal research 46 (3), 268-274, 2009 | 114 | 2009 |
Melatonin target proteins: too many or not enough? L Liu, N Labani, E Cecon, R Jockers Frontiers in endocrinology 10, 492611, 2019 | 101 | 2019 |
Selective protection of the cerebellum against intracerebroventricular LPS is mediated by local melatonin synthesis L Pinato, S da Silveira Cruz-Machado, DG Franco, LMG Campos, ... Brain Structure and Function 220, 827-840, 2015 | 93 | 2015 |
Daily variation of constitutively activated nuclear factor kappa B (NFKB) in rat pineal gland E Cecon, PA Fernandes, L Pinato, ZS Ferreira, RP Markus Chronobiology international 27 (1), 52-67, 2010 | 82 | 2010 |
Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI 3K activity S Owino, A Sánchez‐Bretaño, C Tchio, E Cecon, A Karamitri, J Dam, ... Journal of pineal research 64 (3), e12462, 2018 | 78 | 2018 |
Melatonin inhibits nitric oxide production by microvascular endothelial cells in vivo and in vitro CLM Silva, EK Tamura, SMD Macedo, E Cecon, L Bueno‐Alves, ... British journal of pharmacology 151 (2), 195-205, 2007 | 73 | 2007 |
Molecular basis for defining the pineal gland and pinealocytes as targets for tumor necrosis factor CE Carvalho-Sousa, S da Silveira Cruz-Machado, EK Tamura, ... Frontiers in endocrinology 2, 10, 2011 | 65 | 2011 |
Design and validation of the first cell‐impermeant melatonin receptor agonist F Gbahou, E Cecon, G Viault, R Gerbier, F Jean‐Alphonse, A Karamitri, ... British journal of pharmacology 174 (14), 2409-2421, 2017 | 58 | 2017 |
Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor S Igonet, C Raingeval, E Cecon, M Pučić-Baković, G Lauc, O Cala, ... Scientific Reports 8 (1), 8142, 2018 | 57 | 2018 |
Amyloid β peptide directly impairs pineal gland melatonin synthesis and melatonin receptor signaling through the ERK pathway E Cecon, M Chen, M Marçola, PAC Fernandes, R Jockers, RP Markus The FASEB Journal 29 (6), 2566-2582, 2015 | 56 | 2015 |
Melatonin receptor structures shed new light on melatonin research E Cecon, L Liu, R Jockers Journal of pineal research 67 (4), e12606, 2019 | 53 | 2019 |