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Prashant Rajbhandari, PhD
Prashant Rajbhandari, PhD
E-mail confirmado em mssm.edu - Página inicial
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Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA
T Sallam, M Jones, BJ Thomas, X Wu, T Gilliland, K Qian, A Eskin, ...
Nature medicine 24 (3), 304-312, 2018
1982018
IL-10 signaling remodels adipose chromatin architecture to limit thermogenesis and energy expenditure
P Rajbhandari, BJ Thomas, AC Feng, C Hong, J Wang, L Vergnes, ...
Cell 172 (1), 218-233. e17, 2018
1532018
Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes
P Rajbhandari, D Arneson, SK Hart, IS Ahn, G Diamante, LC Santos, ...
Elife 8, e49501, 2019
1362019
Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress
Z Zhou, V Ribas, P Rajbhandari, BG Drew, TM Moore, AH Fluitt, ...
Journal of Biological Chemistry 293 (13), 4735-4751, 2018
882018
Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation
P Rajbhandari, KA Schalper, NM Solodin, SJ Ellison-Zelski, K Ping Lu, ...
Oncogene 33 (11), 1438-1447, 2014
842014
Regulation of estrogen receptor α N-terminus conformation and function by peptidyl prolyl isomerase Pin1
P Rajbhandari, G Finn, NM Solodin, KK Singarapu, SC Sahu, JL Markley, ...
Molecular and cellular biology, 2012
792012
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling
Z Zhou, TM Moore, BG Drew, V Ribas, J Wanagat, M Civelek, M Segawa, ...
Science translational medicine 12 (555), eaax8096, 2020
782020
A strategy for discovery of endocrine interactions with application to whole-body metabolism
MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ...
Cell metabolism 27 (5), 1138-1155. e6, 2018
672018
Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP
L Zhang, P Rajbhandari, C Priest, J Sandhu, X Wu, R Temel, A Castrillo, ...
Elife 6, e28766, 2017
552017
Prdm4 induction by the small molecule butein promotes white adipose tissue browning
NJ Song, S Choi, P Rajbhandari, SH Chang, S Kim, L Vergnes, SM Kwon, ...
Nature chemical biology 12 (7), 479-481, 2016
522016
RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs
J Wang, P Rajbhandari, A Damianov, A Han, T Sallam, H Waki, ...
The Journal of clinical investigation 127 (3), 987-1004, 2017
362017
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism
S Pearson, A Loft, P Rajbhandari, J Simcox, S Lee, P Tontonoz, ...
Genes & development 33 (13-14), 747-762, 2019
332019
Inhibition of PU. 1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis
Q Liu, J Yu, L Wang, Y Tang, Q Zhou, S Ji, Y Wang, L Santos, ...
Journal of Hepatology 73 (2), 361-370, 2020
282020
Peptidylprolyl isomerase Pin1 directly enhances the DNA binding functions of estrogen receptor α
P Rajbhandari, MS Ozers, NM Solodin, CL Warren, ET Alarid
Journal of Biological Chemistry 290 (22), 13749-13762, 2015
222015
Noggin depletion in adipocytes promotes obesity in mice
AM Blázquez-Medela, M Jumabay, P Rajbhandari, T Sallam, Y Guo, ...
Molecular metabolism 25, 50-63, 2019
202019
The proteasome inhibitor bortezomib induces an inhibitory chromatin environment at a distal enhancer of the estrogen receptor-α gene
GL Powers, P Rajbhandari, NM Solodin, B Bickford, ET Alarid
PloS one 8 (12), e81110, 2013
162013
Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles
RB Kang, Y Li, C Rosselot, T Zhang, M Siddiq, P Rajbhandari, AF Stewart, ...
Genome Medicine 15 (1), 30, 2023
142023
A kinetic model identifies phosphorylated estrogen receptor-α (ERα) as a critical regulator of ERα dynamics in breast cancer
D Tian, NM Solodin, P Rajbhandari, K Bjorklund, ET Alarid, PK Kreeger
The FASEB Journal 29 (5), 2022, 2015
142015
IDOL regulates systemic energy balance through control of neuronal VLDLR expression
SD Lee, C Priest, M Bjursell, J Gao, DV Arneson, IS Ahn, G Diamante, ...
Nature metabolism 1 (11), 1089-1100, 2019
122019
Mammary duct luminal epithelium controls adipocyte thermogenic programme
S Patel, NZR Sparman, D Arneson, A Alvarsson, LC Santos, SJ Duesman, ...
Nature 620 (7972), 192-199, 2023
82023
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