Laércio Pol Fachin
Laércio Pol Fachin
Pós-doutor, Universidade Federal de Pernambuco
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O-glycosylated cell wall proteins are essential in root hair growth
SM Velasquez, MM Ricardi, JG Dorosz, PV Fernandez, AD Nadra, ...
Science 332 (6036), 1401-1403, 2011
GROMOS 53A6GLYC, an Improved GROMOS Force Field for Hexopyranose-Based Carbohydrates
L Pol-Fachin, VH Rusu, H Verli, RD Lins
Journal of Chemical Theory and Computation 8 (11), 4681-4690, 2012
GROMOS96 43a1 performance on the characterization of glycoprotein conformational ensembles through molecular dynamics simulations
L Pol-Fachin, CL Fernandes, H Verli
Carbohydrate research 344 (4), 491-500, 2009
Depiction of the forces participating in the 2-O-sulfo-α-L-iduronic acid conformational preference in heparin sequences in aqueous solutions
L Pol-Fachin, H Verli
Carbohydrate research 343 (9), 1435-1445, 2008
Polymyxin binding to the bacterial outer membrane reveals cation displacement and increasing membrane curvature in susceptible but not in resistant lipopolysaccharide chemotypes
DES Santos, L Pol-Fachin, RD Lins, TA Soares
Journal of chemical information and modeling 57 (9), 2181-2193, 2017
Anticoagulant activity of a unique sulfated pyranosic (1→ 3)-β-L-arabinan through direct interaction with thrombin
PV Fernández, I Quintana, AS Cerezo, JJ Caramelo, L Pol-Fachin, H Verli, ...
Journal of Biological Chemistry 288 (1), 223-233, 2013
GROMOS96 43a1 performance in predicting oligosaccharide conformational ensembles within glycoproteins
CL Fernandes, LG Sachett, L Pol-Fachin, H Verli
Carbohydrate research 345 (5), 663-671, 2010
A unique 2-sulfated β-galactan from the egg jelly of the Sea Urchin Glyptocidaris crenularis conformation flexibility versus induction of the sperm acrosome reaction
MO Castro, VH Pomin, LL Santos, ACES Vilela-Silva, N Hirohashi, ...
Journal of Biological Chemistry 284 (28), 18790-18800, 2009
Mapping Putative B-Cell Zika Virus NS1 Epitopes Provides Molecular Basis for Anti-NS1 Antibody Discrimination between Zika and Dengue Viruses
MCLC Freire, L Pol-Fachin, DF Coêlho, IFT Viana, T Magalhães, ...
ACS Omega 2 (7), 3913-3920, 2017
Extension and validation of the GROMOS 53A6glyc parameter set for glycoproteins
L Pol‐Fachin, H Verli, RD Lins
Journal of computational chemistry 35 (29), 2087-2095, 2014
Low sugar is not always good: Impact of specific O-glycan defects on tip growth in Arabidopsis
SM Velasquez, E Marzol, C Borassi, L Pol-Fachin, MM Ricardi, ...
Plant Physiology, pp. 114.255521, 2015
A cell surface arabinogalactan‐peptide influences root hair cell fate
C Borassi, J Gloazzo Dorosz, MM Ricardi, M Carignani Sardoy, ...
New Phytologist 227 (3), 732-743, 2020
Effects of glycosylation on heparin binding and antithrombin activation by heparin
L Pol‐Fachin, C Franco Becker, J Almeida Guimarães, H Verli
Proteins: Structure, Function, and Bioinformatics 79 (9), 2735-2745, 2011
Atomic Model and Micelle Dynamics of QS-21 Saponin
C Pedebos, L Pol-Fachin, R Pons, CV Teixeira, H Verli
Molecules 19 (3), 3744-3760, 2014
Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding
ES Taylor, L Pol‐Fachin, RD Lins, SK Lower
Proteins: Structure, Function, and Bioinformatics 85 (4), 561-570, 2017
Inhibition of the hemolytic activity caused by Staphylococcus aureus alpha-hemolysin through isatin-Schiff copper (II) complexes
MCA Melo, LR Teixeira, L Pol-Fachin, CG Rodrigues
FEMS microbiology letters 363 (1), fnv207, 2016
Solution conformation and dynamics of exopolysaccharides from Burkholderia species
L Pol-Fachin, RV Serrato, H Verli
Carbohydrate research 345 (13), 1922-1931, 2010
Insights into the N-Sulfation Mechanism: Molecular Dynamics Simulations of the N-Sulfotransferase Domain of Ndst1 and Mutants
TF Gesteira, L Pol-Fachin, VJ Coulson-Thomas, MA Lima, H Verli, ...
PLOS ONE 8 (8), e70880, 2013
Glycosylation is crucial for a proper catalytic site organization in human glucocerebrosidase
L Pol-Fachin, M Siebert, H Verli, ML Saraiva-Pereira
Glycoconjugate Journal 33 (2), 237-244, 2016
The Calcium Goes Meow: Effects of Ions and Glycosylation on Fel d 1, the Major Cat Allergen
R Ligabue-Braun, LG Sachett, L Pol-Fachin, H Verli
PloS one 10 (7), e0132311, 2015
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