Marco van de Weert

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Wim HenninkProfessor, Department of Pharmaceutics, Utrecht University, The NetherlandsE-mail confirmado em uu.nl
Wim JiskootLeiden University, Coriolis PharmaE-mail confirmado em lacdr.leidenuniv.nl
Lorenzo StellaDept of Chemical Science and Technologies, University of Roma Tor VergataE-mail confirmado em stc.uniroma2.it
Vito FoderàProfessor of Biophysics, University of CopenhagenE-mail confirmado em sund.ku.dk
Jesper OstergaardAssociate Professor, Department of Pharmacy, University of CopenhagenE-mail confirmado em sund.ku.dk
Simon BjerregaardLead ScientistE-mail confirmado em ferring.com
Holger GrohganzAssociate Professor, University of CopenhagenE-mail confirmado em sund.ku.dk
Rune Andersen HartvigPostdoc in Biomaterials, University of OsloE-mail confirmado em odont.uio.no
Bruno Sarmentoi3S - University of PortoE-mail confirmado em ineb.up.pt
Lars OlsenDepartment of Drug Design and Pharmacology, University of CopenhagenE-mail confirmado em novozymes.com
Mies J van SteenbergenResearch Technician, Department of Pharmaceutics, Utrecht University, The NetherlandsE-mail confirmado em uu.nl
Parvez I HarisDe Montfort UniversityE-mail confirmado em dmu.ac.uk
Maurizio LeoneRetired Full Professor of Applied Physics, University of PalermoE-mail confirmado em unipa.it
Valeria VetriUniversita' di PalermoE-mail confirmado em unipa.it
Peter W. ThulstrupDepartment of Chemistry, University of CopenhagenE-mail confirmado em chem.ku.dk
Jukka Rantanen, professor PhDUniversity of CopenhagenE-mail confirmado em sund.ku.dk
TW RandolphDepartment of Chemical and Biological Engineering, University of Colorado, BoulderE-mail confirmado em colorado.edu
Marina R. KasimovaNykode PharmaceuticsE-mail confirmado em nykode.com
Frank NijsenAssociate Professor, RadboudumcE-mail confirmado em radboudumc.nl
Flemming Steen JørgensenProfessor, Department of Drug Design and Pharmacology, University of CopenhagenE-mail confirmado em sund.ku.dk

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Marco van de Weert

Associate Professor in Biologics formulation, University of Copenhagen

E-mail confirmado em sund.ku.dk

Protein biophysics Protein aggregation Protein fibrillation Protein-ligand interaction Fluorescence spectroscopy


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Protein instability in poly (lactic-co-glycolic acid) microparticles M van de Weert, WE Hennink, W Jiskoot Pharmaceutical research 17, 1159-1167, 2000	898	2000
Fluorescence quenching and ligand binding: A critical discussion of a popular methodology M Van de Weert, L Stella Journal of Molecular Structure 998 (1-3), 144-150, 2011	602	2011
Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities M Groenning, L Olsen, M van de Weert, JM Flink, S Frokjaer, ... Journal of structural biology 158 (3), 358-369, 2007	300	2007
Fourier transform infrared spectrometric analysis of protein conformation: effect of sampling method and stress factors M van de Weert, PI Haris, WE Hennink, DJA Crommelin Analytical biochemistry 297 (2), 160-169, 2001	294	2001
A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils B Vestergaard, M Groenning, M Roessle, JS Kastrup, M de Weert, ... PLoS biology 5 (5), e134, 2007	288	2007
The effect of a water/organic solvent interface on the structural stability of lysozyme M van de Weert, J Hoechstetter, WE Hennink, DJA Crommelin Journal of controlled release 68 (3), 351-359, 2000	284	2000
Forced degradation of therapeutic proteins A Hawe, M Wiggenhorn, M van de Weert, JHO Garbe, H Mahler, ... Journal of pharmaceutical sciences 101 (3), 895-913, 2012	267	2012
Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation RA Hartvig, M Van De Weert, J Østergaard, L Jorgensen, H Jensen Langmuir 27 (6), 2634-2643, 2011	255	2011
Binding mode of Thioflavin T in insulin amyloid fibrils M Groenning, M Norrman, JM Flink, M van de Weert, JT Bukrinsky, ... Journal of structural biology 159 (3), 483-497, 2007	248	2007
Probing insulin’s secondary structure after entrapment into alginate/chitosan nanoparticles B Sarmento, DC Ferreira, L Jorgensen, M Van De Weert European Journal of Pharmaceutics and Biopharmaceutics 65 (1), 10-17, 2007	226	2007
Fluorescence quenching to study protein-ligand binding: common errors M van de Weert Journal of fluorescence 20, 625-629, 2010	216	2010
Secondary nucleation and accessible surface in insulin amyloid fibril formation V Fodera, F Librizzi, M Groenning, M van de Weert, M Leone The Journal of Physical Chemistry B 112 (12), 3853-3858, 2008	165	2008
Quality by design–Spray drying of insulin intended for inhalation MJ Maltesen, S Bjerregaard, L Hovgaard, S Havelund, M van de Weert European journal of pharmaceutics and biopharmaceutics 70 (3), 828-838, 2008	157	2008
Thermal dissociation and unfolding of insulin K Huus, S Havelund, HB Olsen, M van de Weert, S Frokjaer Biochemistry 44 (33), 11171-11177, 2005	153	2005
Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques M Van De Weert, R van’t Hof, J Van Der Weerd, RMA Heeren, ... Journal of controlled release 68 (1), 31-40, 2000	149	2000
Identification of oxidized methionine in peptides FM Lagerwerf, M van de Weert, W Heerma, J Haverkamp Rapid Communications in Mass Spectrometry 10 (15), 1905-1910, 1996	144	1996
Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass–Prediction of viscosity through protein–protein interaction measurements MS Neergaard, DS Kalonia, H Parshad, AD Nielsen, EH Møller, ... European Journal of Pharmaceutical Sciences 49 (3), 400-410, 2013	141	2013
Drying methods for protein pharmaceuticals MJ Maltesen, M Van De Weert Drug Discovery Today: Technologies 5 (2-3), e81-e88, 2008	137	2008
On the purported “backbone fluorescence” in protein three-dimensional fluorescence spectra A Bortolotti, YH Wong, SS Korsholm, NHB Bahring, S Bobone, S Tayyab, ... Rsc Advances 6 (114), 112870-112876, 2016	125	2016
Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection V Foderà, M Groenning, V Vetri, F Librizzi, S Spagnolo, C Cornett, L Olsen, ... The Journal of Physical Chemistry B 112 (47), 15174-15181, 2008	121	2008

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