J. Christian J. Ray
J. Christian J. Ray
Computational Biologist at Exosome Diagnostics / Bio-Techne
Verified email at
Cited by
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A methodology for performing global uncertainty and sensitivity analysis in systems biology
S Marino, IB Hogue, CJ Ray, DE Kirschner
Journal of theoretical biology 254 (1), 178-196, 2008
Synergy between individual TNF-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection
JCJ Ray, JAL Flynn, DE Kirschner
The Journal of Immunology 182 (6), 3706-3717, 2009
Stress‐response balance drives the evolution of a network module and its host genome
C González, JCJ Ray, M Manhart, RM Adams, D Nevozhay, AV Morozov, ...
Molecular systems biology 11 (8), 827, 2015
Bistable responses in bacterial genetic networks: designs and dynamical consequences
A Tiwari, JCJ Ray, J Narula, OA Igoshin
Mathematical biosciences 231 (1), 76-89, 2011
Adaptive Evolution of the Lactose Utilization Network in Experimentally Evolved Populations of Escherichia coli
S Quan, JCJ Ray, Z Kwota, T Duong, G Balázsi, TF Cooper, RD Monds
PLoS genetics 8 (1), e1002444, 2012
Adaptable functionality of transcriptional feedback in bacterial two-component systems
JCJ Ray, OA Igoshin
PLoS Comput Biol 6 (2), e1000676-e1000676, 2010
The timing of TNF and IFN-γ signaling affects macrophage activation strategies during Mycobacterium tuberculosis infection
JCJ Ray, J Wang, J Chan, DE Kirschner
Journal of theoretical biology 252 (1), 24-38, 2008
Non-transcriptional regulatory processes shape transcriptional network dynamics
JCJ Ray, JJ Tabor, OA Igoshin
Nature Reviews Microbiology 9 (11), 817-828, 2011
A novel metric reveals previously unrecognized distortion in dimensionality reduction of scRNA-Seq data
SM Cooley, T Hamilton, SD Aragones, JCJ Ray, EJ Deeds
Biorxiv, 689851, 2019
Cellular growth arrest and persistence from enzyme saturation
JCJ Ray, ML Wickersheim, AP Jalihal, YO Adeshina, TF Cooper, ...
PLoS Computational Biology 12 (3), e1004825, 2016
Interplay of gene expression noise and ultrasensitive dynamics affects bacterial operon organization
JCJ Ray, OA Igoshin
Public Library of Science 8 (8), e1002672, 2012
The effect of phospholipids and mucin on bacterial internalization in an enterocyte cell culture model
N Usui, C Ray, H Okuyama, RA Drongowski, AG Coran, CM Harmon
Ped Surg Int 15, 150-154, 1999
Amino acid positions subject to multiple co‐evolutionary constraints can be robustly identified by their eigenvector network centrality scores
DJ Parente, JCJ Ray, L Swint‐Kruse
Proteins: Structure, Function, and Bioinformatics, 2015
Requirement for multiple activation signals by anti-inflammatory feedback in macrophages
JCJ Ray, DE Kirschner
Journal of theoretical biology 241 (2), 276-294, 2006
Diversity in lac Operon Regulation among Diverse Escherichia coli Isolates Depends on the Broader Genetic Background but Is Not Explained by Genetic …
KN Phillips, S Widmann, HY Lai, J Nguyen, JCJ Ray, G Balázsi, ...
Mbio 10 (6), 10.1128/mbio. 02232-19, 2019
Lineage space and the propensity of bacterial cells to undergo growth transitions
A Bandyopadhyay, H Wang, JCJ Ray
PLOS Computational Biology 14 (8), e1006380, 2018
Computation by natural systems
D Chu, M Prokopenko, JCJ Ray
Interface Focus 8 (6), 20180058, 2018
Survival of phenotypic information during cellular growth transitions
ACS Synthetic Biology 5 (8), 810-816, 2016
A framework for evaluating edited cell libraries created by massively parallel genome engineering
S Cawley, E Abbate, CG Abraham, S Alvarez, M Barber, S Bolte, J Bruand, ...
bioRxiv, 2021.09. 23.458228, 2021
Signatures of antibiotic tolerance and persistence in response to divergent stresses
H Wang, GW McElfresh, N Wijesuriya, A Podgorny, AD Hecht, JCJ Ray
bioRxiv, 2023.02. 05.527212, 2023
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Articles 1–20