| Resistance to the antibody–drug conjugate T-DM1 is based in a reduction in lysosomal proteolytic activity C Ríos-Luci, S García-Alonso, E Díaz-Rodríguez, M Nadal-Serrano, ... Cancer research 77 (17), 4639-4651, 2017 | 122 | 2017 |
| Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol EL Bonifazi, C Ríos-Luci, LG León, G Burton, JM Padrón, RI Misico Bioorganic & medicinal chemistry 18 (7), 2621-2630, 2010 | 93 | 2010 |
| Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand CM Santos, S Cabrera, C Rios-Luci, JM Padrón, IL Solera, AG Quiroga, ... Dalton Transactions 42 (37), 13343-13348, 2013 | 72 | 2013 |
| Antiproliferative activity of novel benzo [b][1, 6] naphthyridines in human solid tumor cell lines S Rudys, C Ríos-Luci, E Pérez-Roth, I Cikotiene, JM Padrón Bioorganic & Medicinal Chemistry Letters 20 (5), 1504-1506, 2010 | 63 | 2010 |
| Heterometallic platinum (II) compounds with β-aminoethylferrocenes: synthesis, electrochemical behaviour and anticancer activity D Nieto, AM González-Vadillo, S Bruña, CJ Pastor, C Ríos-Luci, LG León, ... Dalton Transactions 41 (2), 432-441, 2012 | 55 | 2012 |
| β-Lapachone analogs with enhanced antiproliferative activity C Ríos-Luci, EL Bonifazi, LG Leon, JC Montero, G Burton, A Pandiella, ... European journal of medicinal chemistry 53, 264-274, 2012 | 50 | 2012 |
| Reactivity and Biological Properties of a Series of Cytotoxic PtI2(amine)2 Complexes, Either cis or trans Configured L Messori, L Cubo, C Gabbiani, A Alvarez-Valdes, E Michelucci, ... Inorganic Chemistry 51 (3), 1717-1726, 2012 | 48 | 2012 |
| Model‐based nanoengineered pharmacokinetics of iron‐doped copper oxide for nanomedical applications H Naatz, BB Manshian, C Rios Luci, V Tsikourkitoudi, Y Deligiannakis, ... Angewandte Chemie 132 (5), 1844-1852, 2020 | 46 | 2020 |
| Cytotoxic profile and peculiar reactivity with biomolecules of a novel “rule-breaker” iodidoplatinum (II) complex L Messori, A Casini, C Gabbiani, E Michelucci, L Cubo, C Rios-Luci, ... ACS medicinal chemistry letters 1 (8), 381-385, 2010 | 40 | 2010 |
| Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitis-idaea and Maytenus spinosa MTR de Almeida, C Ríos-Luci, JM Padrón, JA Palermo Phytochemistry 71 (14-15), 1741-1748, 2010 | 37 | 2010 |
| Anti-inflammatory activity of a novel family of aryl ureas compounds in an endotoxin-induced airway epithelial cell injury model NE Cabrera-Benitez, E Pérez-Roth, M Casula, A Ramos-Nuez, ... PLoS One 7 (11), e48468, 2012 | 32 | 2012 |
| Enhancement of antiproliferative activity by molecular simplification of catalpol C García, LG León, CR Pungitore, C Ríos-Luci, AH Daranas, JC Montero, ... Bioorganic & medicinal chemistry 18 (7), 2515-2523, 2010 | 32 | 2010 |
| Antiproliferative activity of dmoPTA–Ru (II) complexes against human solid tumor cells C Ríos-Luci, LG León, A Mena-Cruz, E Pérez-Roth, P Lorenzo-Luis, ... Bioorganic & medicinal chemistry letters 21 (15), 4568-4571, 2011 | 30 | 2011 |
| QSAR on antiproliferative naphthoquinones based on a conformation-independent approach PR Duchowicz, DO Bennardi, DE Bacelo, EL Bonifazi, C Rios-Luci, ... European Journal of Medicinal Chemistry 77, 176-184, 2014 | 28 | 2014 |
| Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation J Alemán, V del Solar, A Alvarez-Valdés, C Ríos-Luci, JM Padrón, ... MedChemComm 2 (8), 789-793, 2011 | 27 | 2011 |
| Mitotic arrest induced by a novel family of DNA topoisomerase II inhibitors LG León, C Ríos-Luci, D Tejedor, E Pérez-Roth, JC Montero, A Pandiella, ... Journal of medicinal chemistry 53 (9), 3835-3839, 2010 | 24 | 2010 |
| Expanding the synthesis of new trans-sulfonamide platinum complexes: cytotoxicity, SAR, fluorescent cell assays and stability studies V Del Solar, A Quinones-Lombrana, S Cabrera, JM Padron, C Rios-Luci, ... Journal of Inorganic Biochemistry 127, 128-140, 2013 | 23 | 2013 |
| DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells A Podolski-Renić, J Banković, J Dinić, C Ríos-Luci, MX Fernandes, ... European Journal of Pharmaceutical Sciences 105, 159-168, 2017 | 22 | 2017 |
| Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides E Pudziuvelyte, C Ríos-Luci, LG León, I Cikotiene, JM Padrón Bioorganic & medicinal chemistry 17 (14), 4955-4960, 2009 | 21 | 2009 |
| TRAIL receptor activation overcomes resistance to trastuzumab in HER2 positive breast cancer cells E Díaz-Rodríguez, J Pérez-Peña, C Ríos-Luci, J Arribas, A Ocaña, ... Cancer Letters 453, 34-44, 2019 | 17 | 2019 |
