Seguir
Joachim Brouwers
Joachim Brouwers
E-mail confirmado em pharm.kuleuven.be
Título
Citado por
Citado por
Ano
Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?
J Brouwers, ME Brewster, P Augustijns
Journal of pharmaceutical sciences 98 (8), 2549-2572, 2009
10072009
In vitro models for the prediction of in vivo performance of oral dosage forms
ES Kostewicz, B Abrahamsson, M Brewster, J Brouwers, J Butler, ...
European Journal of Pharmaceutical Sciences 57, 342-366, 2014
3972014
In vivo methods for drug absorption–comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient …
E Sjögren, B Abrahamsson, P Augustijns, D Becker, MB Bolger, ...
European Journal of Pharmaceutical Sciences 57, 99-151, 2014
2972014
Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
BJ Boyd, CAS Bergström, Z Vinarov, M Kuentz, J Brouwers, P Augustijns, ...
European Journal of Pharmaceutical Sciences 137, 104967, 2019
2892019
Evaluation of gastrointestinal drug supersaturation and precipitation: strategies and issues
J Bevernage, J Brouwers, ME Brewster, P Augustijns
International journal of pharmaceutics 453 (1), 25-35, 2013
2792013
Characterization of human duodenal fluids in fasted and fed state conditions
D Riethorst, R Mols, G Duchateau, J Tack, J Brouwers, P Augustijns
Journal of pharmaceutical sciences 105 (2), 673-681, 2016
2292016
A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption
P Augustijns, B Wuyts, B Hens, P Annaert, J Butler, J Brouwers
European Journal of Pharmaceutical Sciences 57, 322-332, 2014
2012014
Drug permeability profiling using cell-free permeation tools: Overview and applications
P Berben, A Bauer-Brandl, M Brandl, B Faller, GE Flaten, AC Jacobsen, ...
European Journal of Pharmaceutical Sciences 119, 219-233, 2018
1892018
Excipient-mediated supersaturation stabilization in human intestinal fluids
J Bevernage, T Forier, J Brouwers, J Tack, P Annaert, P Augustijns
Molecular pharmaceutics 8 (2), 564-570, 2011
1642011
Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations
J Walravens, J Brouwers, I Spriet, J Tack, P Annaert, P Augustijns
Clinical pharmacokinetics 50, 725-734, 2011
1432011
Intestinal drug solubility estimation based on simulated intestinal fluids: comparison with solubility in human intestinal fluids
S Clarysse, J Brouwers, J Tack, P Annaert, P Augustijns
European Journal of Pharmaceutical Sciences 43 (4), 260-269, 2011
1362011
Drug precipitation–permeation interplay: supersaturation in an absorptive environment
J Bevernage, J Brouwers, P Annaert, P Augustijns
European journal of pharmaceutics and biopharmaceutics 82 (2), 424-428, 2012
1332012
Postprandial changes in solubilizing capacity of human intestinal fluids for BCS class II drugs
S Clarysse, D Psachoulias, J Brouwers, J Tack, P Annaert, G Duchateau, ...
Pharmaceutical research 26, 1456-1466, 2009
1332009
Supersaturation and precipitation of posaconazole upon entry in the upper small intestine in humans
B Hens, J Brouwers, M Corsetti, P Augustijns
Journal of pharmaceutical sciences 105 (9), 2677-2684, 2016
1192016
In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration
J Butler, B Hens, M Vertzoni, J Brouwers, P Berben, J Dressman, ...
European Journal of Pharmaceutics and Biopharmaceutics 136, 70-83, 2019
1172019
Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: a case study with amprenavir
J Brouwers, J Tack, F Lammert, P Augustijns
Journal of pharmaceutical sciences 95 (2), 372-383, 2006
1172006
Drug supersaturation in simulated human intestinal fluids representing different nutritional states
J Bevernage, J Brouwers, S Clarysse, M Vertzoni, JAN Tack, P Annaert, ...
Journal of pharmaceutical sciences 99 (11), 4525-4534, 2010
1122010
Exploring gastrointestinal variables affecting drug and formulation behavior: methodologies, challenges and opportunities
B Hens, M Corsetti, R Spiller, L Marciani, T Vanuytsel, J Tack, A Talattof, ...
International Journal of Pharmaceutics 519 (1-2), 79-97, 2017
1062017
Food-dependent disintegration of immediate release fosamprenavir tablets: in vitro evaluation using magnetic resonance imaging and a dynamic gastrointestinal system
J Brouwers, B Anneveld, GJ Goudappel, G Duchateau, P Annaert, ...
European Journal of Pharmaceutics and Biopharmaceutics 77 (2), 313-319, 2011
1042011
Gastrointestinal behavior of nano-and microsized fenofibrate: in vivo evaluation in man and in vitro simulation by assessment of the permeation potential
B Hens, J Brouwers, M Corsetti, P Augustijns
European Journal of Pharmaceutical Sciences 77, 40-47, 2015
962015
O sistema não pode executar a operação agora. Tente novamente mais tarde.
Artigos 1–20