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Gareth G Lavery
Gareth G Lavery
E-mail confirmado em ntu.ac.uk
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11β-Hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response
JW Tomlinson, EA Walker, IJ Bujalska, N Draper, GG Lavery, MS Cooper, ...
Endocrine reviews 25 (5), 831-866, 2004
11962004
Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass …
N Krone, BA Hughes, GG Lavery, PM Stewart, W Arlt, CHL Shackleton
The Journal of steroid biochemistry and molecular biology 121 (3-5), 496-504, 2010
4552010
Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency
N Draper, EA Walker, IJ Bujalska, JW Tomlinson, SM Chalder, W Arlt, ...
Nature genetics 34 (4), 434-439, 2003
3702003
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ...
Cell reports 28 (7), 1717-1728. e6, 2019
3012019
Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy
N Diguet, SAJ Trammell, C Tannous, R Deloux, J Piquereau, N Mougenot, ...
Circulation 137 (21), 2256-2273, 2018
2972018
11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess
SA Morgan, EL McCabe, LL Gathercole, ZK Hassan-Smith, DP Larner, ...
Proceedings of the National Academy of Sciences 111 (24), E2482-E2491, 2014
2812014
Hexose-6-phosphate dehydrogenase knock-out mice lack 11β-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation
GG Lavery, EA Walker, N Draper, P Jeyasuria, J Marcos, CHL Shackleton, ...
Journal of Biological Chemistry 281 (10), 6546-6551, 2006
2462006
Targeted disruption of β-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex
AC Kim, AL Reuter, M Zubair, T Else, K Serecky, NC Bingham, GG Lavery, ...
Oxford University Press for The Company of Biologists Limited 135 (15), 2593 …, 2008
2292008
11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects
LL Gathercole, GG Lavery, SA Morgan, MS Cooper, AJ Sinclair, ...
Endocrine reviews 34 (4), 525-555, 2013
2062013
11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle
SA Morgan, M Sherlock, LL Gathercole, GG Lavery, C Lenaghan, ...
Diabetes 58 (11), 2506-2515, 2009
2022009
CA-Repeat polymorphism in intron 1 of HSD11B2: effects on gene expression and salt sensitivity
AK Agarwal, G Giacchetti, G Lavery, H Nikkila, M Palermo, M Ricketts, ...
Hypertension 36 (2), 187-194, 2000
1682000
Premature adrenarche: novel lessons from early onset androgen excess
J Idkowiak, GG Lavery, V Dhir, TG Barrett, PM Stewart, N Krone, W Arlt
European Journal of Endocrinology 165 (2), 189-207, 2011
1652011
11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects
A Tiganescu, AA Tahrani, SA Morgan, M Otranto, A Desmoulière, ...
The Journal of clinical investigation 123 (7), 3051-3060, 2013
1382013
Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin‐resistant men
OL Dollerup, S Chubanava, M Agerholm, SD Søndergård, A Altıntaş, ...
The Journal of physiology 598 (4), 731-754, 2020
1152020
A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics
MW O’Reilly, CSJ Westgate, C Hornby, H Botfield, AE Taylor, K Markey, ...
JCI insight 4 (6), 2019
1152019
Prereceptor regulation of glucocorticoid action by 11β‐hydroxysteroid dehydrogenase: a novel determinant of cell proliferation
EH Rabbitt, GG Lavery, EA Walker, MS Cooper, PM Stewart, M Hewison
The FASEB journal 16 (1), 36-44, 2002
1142002
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner
AP Seabright, NHF Fine, JP Barlow, SO Lord, I Musa, A Gray, JA Bryant, ...
The FASEB Journal 34 (5), 6284, 2020
1112020
Association studies between microsatellite markers within the gene encoding human 11β-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and …
N Draper, SM Echwald, GG Lavery, EA Walker, R Fraser, E Davies, ...
The Journal of Clinical Endocrinology & Metabolism 87 (11), 4984-4990, 2002
1102002
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
RS Fletcher, J Ratajczak, CL Doig, LA Oakey, R Callingham, GDS Xavier, ...
Molecular metabolism 6 (8), 819-832, 2017
1062017
Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency
GG Lavery, EA Walker, A Tiganescu, JP Ride, CHL Shackleton, ...
The Journal of Clinical Endocrinology & Metabolism 93 (10), 3827-3832, 2008
1052008
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