| 11β-Hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response JW Tomlinson, EA Walker, IJ Bujalska, N Draper, GG Lavery, MS Cooper, ... Endocrine reviews 25 (5), 831-866, 2004 | 1118 | 2004 |
| Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass … N Krone, BA Hughes, GG Lavery, PM Stewart, W Arlt, CHL Shackleton The Journal of steroid biochemistry and molecular biology 121 (3-5), 496-504, 2010 | 378 | 2010 |
| Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency N Draper, EA Walker, IJ Bujalska, JW Tomlinson, SM Chalder, W Arlt, ... Nature genetics 34 (4), 434-439, 2003 | 353 | 2003 |
| Hexose-6-phosphate dehydrogenase knock-out mice lack 11β-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation GG Lavery, EA Walker, N Draper, P Jeyasuria, J Marcos, CHL Shackleton, ... Journal of Biological Chemistry 281 (10), 6546-6551, 2006 | 238 | 2006 |
| 11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess SA Morgan, EL McCabe, LL Gathercole, ZK Hassan-Smith, DP Larner, ... Proceedings of the National Academy of Sciences 111 (24), E2482-E2491, 2014 | 221 | 2014 |
| Targeted disruption of β-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex AC Kim, AL Reuter, M Zubair, T Else, K Serecky, NC Bingham, GG Lavery, ... Oxford University Press for The Company of Biologists Limited 135 (15), 2593 …, 2008 | 209 | 2008 |
| 11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle SA Morgan, M Sherlock, LL Gathercole, GG Lavery, C Lenaghan, ... Diabetes 58 (11), 2506-2515, 2009 | 182 | 2009 |
| Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy N Diguet, SAJ Trammell, C Tannous, R Deloux, J Piquereau, N Mougenot, ... Circulation 137 (21), 2256-2273, 2018 | 179 | 2018 |
| Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ... Cell reports 28 (7), 1717-1728. e6, 2019 | 171 | 2019 |
| 11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects LL Gathercole, GG Lavery, SA Morgan, MS Cooper, AJ Sinclair, ... Endocrine reviews 34 (4), 525-555, 2013 | 169 | 2013 |
| CA-Repeat polymorphism in intron 1 of HSD11B2: effects on gene expression and salt sensitivity AK Agarwal, G Giacchetti, G Lavery, H Nikkila, M Palermo, M Ricketts, ... Hypertension 36 (2), 187-194, 2000 | 166 | 2000 |
| Premature adrenarche: novel lessons from early onset androgen excess J Idkowiak, GG Lavery, V Dhir, TG Barrett, PM Stewart, N Krone, W Arlt European Journal of Endocrinology 165 (2), 189, 2011 | 150 | 2011 |
| 11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects A Tiganescu, AA Tahrani, SA Morgan, M Otranto, A Desmoulière, ... The Journal of clinical investigation 123 (7), 3051-3060, 2013 | 126 | 2013 |
| Prereceptor regulation of glucocorticoid action by 11β‐hydroxysteroid dehydrogenase: a novel determinant of cell proliferation EH Rabbitt, GG Lavery, EA Walker, MS Cooper, PM Stewart, M Hewison The FASEB journal 16 (1), 36-44, 2002 | 114 | 2002 |
| Association studies between microsatellite markers within the gene encoding human 11β-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and … N Draper, SM Echwald, GG Lavery, EA Walker, R Fraser, E Davies, ... The Journal of Clinical Endocrinology & Metabolism 87 (11), 4984-4990, 2002 | 105 | 2002 |
| Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency GG Lavery, EA Walker, A Tiganescu, JP Ride, CHL Shackleton, ... The Journal of Clinical Endocrinology & Metabolism 93 (10), 3827-3832, 2008 | 97 | 2008 |
| Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy GG Lavery, EA Walker, N Turan, D Rogoff, JW Ryder, JM Shelton, ... Journal of Biological Chemistry 283 (13), 8453-8461, 2008 | 86 | 2008 |
| Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice JK Dowman, LJ Hopkins, GM Reynolds, MJ Armstrong, M Nasiri, ... Endocrinology 154 (12), 4536-4547, 2013 | 79 | 2013 |
| Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells RS Fletcher, J Ratajczak, CL Doig, LA Oakey, R Callingham, GDS Xavier, ... Molecular metabolism 6 (8), 819-832, 2017 | 76 | 2017 |
| Targeting NAD+ in metabolic disease: New insights into an old molecule YS Elhassan, AA Philp, GG Lavery Journal of the Endocrine Society 1 (7), 816-835, 2017 | 74 | 2017 |
Jeremy TomlinsonUniversity of OxfordE-mail confirmado em ocdem.ox.ac.uk
