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Euan Parnell
Euan Parnell
E-mail confirmado em northwestern.edu - Página inicial
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Dendritic structural plasticity and neuropsychiatric disease
MP Forrest, E Parnell, P Penzes
Nature Reviews Neuroscience 19 (4), 215-234, 2018
4042018
The future of EPAC-targeted therapies: agonism versus antagonism
E Parnell, TM Palmer, SJ Yarwood
Trends in pharmacological sciences 36 (4), 203-214, 2015
902015
Regulation of the inflammatory response of vascular endothelial cells by EPAC1
E Parnell, BO Smith, TM Palmer, A Terrin, M Zaccolo, SJ Yarwood
British journal of pharmacology 166 (2), 434-446, 2012
712012
Partial loss of USP9X function leads to a male neurodevelopmental and behavioral disorder converging on transforming growth factor β signaling
BV Johnson, R Kumar, S Oishi, S Alexander, M Kasherman, MS Vega, ...
Biological psychiatry 87 (2), 100-112, 2020
452020
The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal
E Parnell, BO Smith, SJ Yarwood
Cellular signalling 27 (5), 989-996, 2015
412015
Usp9X controls ankyrin-repeat domain protein homeostasis during dendritic spine development
S Yoon, E Parnell, M Kasherman, MP Forrest, K Myczek, S Premarathne, ...
Neuron 105 (3), 506-521. e7, 2020
382020
Identification of a novel, small molecule partial agonist for the cyclic AMP sensor, EPAC1
E Parnell, SP McElroy, J Wiejak, GL Baillie, A Porter, DR Adams, ...
Scientific reports 7 (1), 294, 2017
352017
KALRN: A central regulator of synaptic function and synaptopathies
E Parnell, LP Shapiro, RA Voorn, MP Forrest, HA Jalloul, DD Loizzo, ...
Gene 768, 145306, 2021
272021
Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells
E Parnell, A Koschinski, M Zaccolo, RT Cameron, GS Baillie, GL Baillie, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (7), 1749-1758, 2015
232015
Missense variant contribution to USP9X-female syndrome
LA Jolly, E Parnell, AE Gardner, MA Corbett, LA Pérez-Jurado, M Shaw, ...
NPJ Genomic Medicine 5 (1), 53, 2020
212020
The potential of a novel class of EPAC-selective agonists to combat cardiovascular inflammation
G Barker, E Parnell, B Van Basten, H Buist, DR Adams, SJ Yarwood
Journal of Cardiovascular Development and Disease 4 (4), 22, 2017
192017
Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
MD Martín-de-Saavedra, M Dos Santos, L Culotta, O Varea, BP Spielman, ...
Neuron 110 (4), 627-643. e9, 2022
182022
Interactions between Epac1 and ezrin in the control of endothelial barrier function
E Parnell, SJ Yarwood
Biochemical Society Transactions 42 (2), 274-278, 2014
162014
TGF-β-induced phosphorylation of Usp9X stabilizes ankyrin-G and regulates dendritic spine development and maintenance
S Yoon, E Parnell, P Penzes
Cell reports 31 (8), 2020
132020
Identification of a novel class of benzofuran oxoacetic acid-derived ligands that selectively activate cellular EPAC1
E M. Beck, E Parnell, A Cowley, A Porter, J Gillespie, J Robinson, ...
Cells 8 (11), 1425, 2019
122019
Excitatory dysfunction drives network and calcium handling deficits in 16p11. 2 duplication schizophrenia induced pluripotent stem cell–derived neurons
E Parnell, L Culotta, MP Forrest, HA Jalloul, BL Eckman, DD Loizzo, ...
Biological psychiatry 94 (2), 153-163, 2023
102023
The cyclic AMP phosphodiesterase 4D5 (PDE4D5)/receptor for activated C-kinase 1 (RACK1) signalling complex as a sensor of the extracellular nano-environment
SJ Yarwood, E Parnell, RJ Bird
Cellular Signalling 35, 282-289, 2017
72017
A developmental delay linked missense mutation in Kalirin-7 disrupts protein function and neuronal morphology
E Parnell, RA Voorn, MD Martin-de-Saavedra, DD Loizzo, M Dos Santos, ...
Frontiers in Molecular Neuroscience 15, 994513, 2022
12022
Tunneling nanotubes at the microglia‐neuron interface in neuroinflammation and Alzheimer’s disease
CR Zaccard, E Parnell, I Gippo, C Geula, P Penzes
Alzheimer's & Dementia 19, e076872, 2023
2023
ECTODOMAIN SHEDDING AND NEURODEVELOPMENTAL DISORDERS
MD Martín-De-Saavedra, M Dos Santos, L Culotta, O Varea, B Spielman, ...
IBRO Neuroscience Reports 15, S52, 2023
2023
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