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Fredy RS Gutierrez MD, MSc, PhD
Fredy RS Gutierrez MD, MSc, PhD
Assoc. Dir. Medical A (Oncology) - Merck Sharp & Dohme Corp.
E-mail confirmado em merck.com - Página inicial
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Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania
DS Lima-Junior, DL Costa, V Carregaro, LD Cunha, ALN Silva, ...
Nature medicine 19 (7), 909-915, 2013
3962013
The role of parasite persistence in pathogenesis of Chagas heart disease
FRS Gutierrez, PMM Guedes, RT Gazzinelli, JS Silva
Parasite immunology 31 (11), 673-685, 2009
2242009
IL-17 Produced during Trypanosoma cruzi Infection Plays a Central Role in Regulating Parasite-Induced Myocarditis
PMM Guedes, FRS Gutierrez, FL Maia, CM Milanezi, GK Silva, ...
PLoS neglected tropical diseases 4 (2), e604, 2010
1942010
Current status of Chagas disease chemotherapy
PMM Guedes, GK Silva, FRS Gutierrez, JS Silva
Expert review of anti-infective therapy 9 (5), 609-620, 2011
1502011
The effects of nitric oxide on the immune system during Trypanosoma cruzi infection
FRS Gutierrez, TWP Mineo, WR Pavanelli, PMM Guedes, JS Silva
Memórias do Instituto Oswaldo Cruz 104, 236-245, 2009
1502009
Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection
GK Silva, FRS Gutierrez, PMM Guedes, CV Horta, LD Cunha, TWP Mineo, ...
The journal of immunology 184 (3), 1148-1152, 2010
1472010
Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease
PMM Guedes, FRS Gutierrez, GK Silva, R Dellalibera-Joviliano, ...
PLoS Neglected Tropical Diseases 6 (4), e1630, 2012
1412012
Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental …
FRS Gutierrez, MM Lalu, FS Mariano, CM Milanezi, C Jonathan, ...
The Journal of infectious diseases 197 (10), 1468-1476, 2008
1262008
The involvement of CD4+CD25+ T cells in the acute phase of Trypanosoma cruzi infection
FS Mariano, FRS Gutierrez, WR Pavanelli, CM Milanezi, KA Cavassani, ...
Microbes and Infection 10 (7), 825-833, 2008
1202008
Apoptosis-associated Speck–like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection
GK Silva, RS Costa, TN Silveira, BC Caetano, CV Horta, FRS Gutierrez, ...
The Journal of Immunology 191 (6), 3373-3383, 2013
1002013
Spurious alternative impact factors: The scale of the problem from an academic perspective
FRS Gutierrez, J Beall, DA Forero
BioEssays 37 (5), 474-476, 2015
942015
Statins as Modulators of Regulatory T-Cell Biology
DA Forero-Peña, FRS Gutierrez
Mediators of Inflammation 213 (Article ID 167086), 1-10, 2013
922013
Complexation of the anti-Trypanosoma cruzi drug benznidazole improves solubility and efficacy
JJ Nogueira Silva, WR Pavanelli, FR Salazar Gutierrez, FC Alves Lima, ...
Journal of medicinal chemistry 51 (14), 4104-4114, 2008
792008
Recognition by toll‐like receptor 2 induces antigen‐presenting cell activation and Th1 programming during infection by Neospora caninum
TWP Mineo, CJF Oliveira, FRS Gutierrez, JS Silva
Immunology and cell biology 88 (8), 825-833, 2010
742010
Nitric oxide donor trans‐[RuCl([15]aneN4)NO]2+ as a possible therapeutic approach for Chagas' disease
PMM Guedes, FS Oliveira, FRS Gutierrez, GK da Silva, GJ Rodrigues, ...
British journal of pharmacology 160 (2), 270-282, 2010
642010
Regulation of Trypanosoma cruzi-Induced Myocarditis by Programmed Death Receptor 1
FRS Gutierrez, FS Mariano, CJF Oliveira, WR Pavanelli, PMM Guedes, ...
Infection and immunity 79 (5), 1873, 2011
602011
Tick saliva induces regulatory dendritic cells: MAP-kinases and Toll-like receptor-2 expression as potential targets
CJF Oliveira, WA Carvalho, GR Garcia, FRS Gutierrez, ...
Veterinary parasitology 167 (2-4), 288-297, 2010
602010
5-lipoxygenase is a key determinant of acute myocardial inflammation and mortality during Trypanosoma cruzi infection
WR Pavanelli, FRS Gutierrez, FS Mariano, CM Prado, BR Ferreira, ...
Microbes and Infection 12 (8-9), 587-597, 2010
482010
Antiparasitical chemotherapy in Chagas’ disease cardiomyopathy: current evidence
PM Matta Guedes, FR Gutierrez, MS Nascimento, MA Do-Valle-Matta, ...
Tropical Medicine & International Health 17 (9), 1057-1065, 2012
312012
PD‐1 modulates steady‐state and infection‐induced IL‐10 production in vivo
C McBerry, A Dias, N Shryock, K Lampe, FRS Gutierrez, L Boon, ...
European journal of immunology 44 (2), 469-479, 2014
272014
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