| Commensal bacteria make GPCR ligands that mimic human signalling molecules LJ Cohen, D Esterhazy, SH Kim, C Lemetre, RR Aguilar, EA Gordon, ... Nature 549 (7670), 48-53, 2017 | 472 | 2017 |
| A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution SL Cockroft, J Chu, M Amorin, MR Ghadiri Journal of the American Chemical Society 130 (3), 818-820, 2008 | 325 | 2008 |
| Discovery of MRSA active antibiotics using primary sequence from the human microbiome J Chu, X Vila-Farres, D Inoyama, M Ternei, LJ Cohen, EA Gordon, ... Nature Chemical Biology 12 (12), 1004-1006, 2016 | 215 | 2016 |
| Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist LJ Cohen, HS Kang, J Chu, YH Huang, EA Gordon, BVB Reddy, ... Proceedings of the National Academy of Sciences 112 (35), E4825-E4834, 2015 | 195 | 2015 |
| Antimicrobials inspired by nonribosomal peptide synthetase gene clusters X Vila-Farres, J Chu, D Inoyama, MA Ternei, C Lemetre, LJ Cohen, ... Journal of the American Chemical Society 139 (4), 1404-1407, 2017 | 66 | 2017 |
| Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore J Chu, M González-López, SL Cockroft, M Amorin, MR Ghadiri Angewandte Chemie (International ed. in English) 49 (52), 10106, 2010 | 60 | 2010 |
| Synthetic-bioinformatic natural product antibiotics with diverse modes of action J Chu, B Koirala, N Forelli, X Vila-Farres, MA Ternei, T Ali, DA Colosimo, ... Journal of the American Chemical Society 142 (33), 14158-14168, 2020 | 53 | 2020 |
| Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology DC Cole, Y Chung, K Gagnidze, KH Hajdarovic, V Rayon-Estrada, ... Proceedings of the National Academy of Sciences 114 (50), 13272-13277, 2017 | 45 | 2017 |
| Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus) C HUANG, KO, HUNG, CHU, WANG Biochemical Journal 378 (2), 399-407, 2004 | 45 | 2004 |
| Bioactive synthetic-bioinformatic natural product cyclic peptides inspired by nonribosomal peptide synthetase gene clusters from the human microbiome J Chu, X Vila-Farres, SF Brady Journal of the American Chemical Society 141 (40), 15737-15741, 2019 | 43 | 2019 |
| Human Microbiome Inspired Antibiotics with Improved β-Lactam Synergy against MDR Staphylococcus aureus J Chu, X Vila-Farres, D Inoyama, R Gallardo-Macias, M Jaskowski, ... ACS infectious diseases 4 (1), 33-38, 2018 | 41 | 2018 |
| A β-Boronopeptide Bundle of Known Structure As a Vehicle for Polyol Recognition S Melicher, Chu, Walker, Miller, Baxter organic letters 15 (19), 5048-5051, 2013 | 31 | 2013 |
| An Optimized Synthetic-Bioinformatic Natural Product Antibiotic Sterilizes Multidrug-Resistant Acinetobacter baumannii-Infected Wounds X Vila-Farres, J Chu, MA Ternei, C Lemetre, S Park, DS Perlin, SF Brady mSphere 3 (1), e00528-17, 2018 | 20 | 2018 |
| Disrupting Transcription and Folate Biosynthesis Leads to Synergistic Suppression of Escherichia coli Growth PH Chen, LK Sung, JD Hegemann, J Chu ChemMedChem 17 (10), e202200075, 2022 | 7 | 2022 |
| Characterization and Structural Determination of CmnG‐A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis IH Chen, T Cheng, YL Wang, SJ Huang, YH Hsiao, YT Lai, SI Toh, J Chu, ... ChemBioChem 23 (24), e202200563, 2022 | 6 | 2022 |
| Total synthesis and antimicrobial evaluation of pagoamide A CH Wu, J Chu Frontiers in Chemistry 9, 741290, 2021 | 6 | 2021 |
| Reaction tracking and high-throughput screening of active compounds in combinatorial chemistry by tandem mass spectrometry molecular networking HH Chung, CY Kao, TSA Wang, J Chu, J Pei, CC Hsu Analytical Chemistry 93 (4), 2456-2463, 2021 | 6 | 2021 |
| Bioinformatic analysis reveals both oversampled and underexplored biosynthetic diversity in nonribosomal peptides BS Jian, SL Chiou, CC Hsu, J Ho, YW Wu, J Chu ACS Chemical Biology 18 (3), 476-483, 2023 | 4 | 2023 |
| Correction: Corrigendum: Commensal bacteria make GPCR ligands that mimic human signalling molecules LJ Cohen, D Esterhazy, SH Kim, C Lemetre, RR Aguilar, EA Gordon, ... Nature 556 (7699), 135-135, 2018 | 4 | 2018 |
| Structure Prediction and Protein Engineering Yield New Insights into Microcin J25 Precursor Recognition HN Tan, WQ Liu, J Ho, YJ Chen, FJ Shieh, HT Liao, SP Wang, ... ACS Chemical Biology 19 (9), 1982-1990, 2024 | 3 | 2024 |
