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Horacio Botti
Horacio Botti
Adjunct Profesor, Integrative Biophysics Laboratory, Depto. de Biofísica, Facultad de Medicina
E-mail confirmado em pasteur.edu.uy
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Factors affecting protein thiol reactivity and specificity in peroxide reduction
G Ferrer-Sueta, B Manta, H Botti, R Radi, M Trujillo, A Denicola
Chemical research in toxicology 24 (4), 434-450, 2011
3292011
Reactivity of sulfenic acid in human serum albumin
L Turell, H Botti, S Carballal, G Ferrer-Sueta, JM Souza, R Durán, ...
Biochemistry 47 (1), 358-367, 2008
1972008
Direct measurement of nitric oxide and oxygen partitioning into liposomes and low density lipoprotein
M Moller, H Botti, C Batthyany, H Rubbo, R Radi, A Denicola
Journal of Biological Chemistry 280 (10), 8850-8854, 2005
1722005
Sulfenic acid in human serum albumin
S Carballal, B Alvarez, L Turell, H Botti, BA Freeman, R Radi
Amino acids 32, 543-551, 2007
1582007
Interactions of nitric oxide and peroxynitrite with low-density lipoprotein
H Rubbo, A Trostchansky, H Botti, C Batthyány
Walter de Gruyter 383 (3-4), 547-552, 2002
1512002
Thiol and Sulfenic Acid Oxidation of AhpE, the One-Cysteine Peroxiredoxin from Mycobacterium tuberculosis: Kinetics, Acidity Constants, and Conformational …
M Hugo, L Turell, B Manta, H Botti, G Monteiro, LES Netto, B Alvarez, ...
Biochemistry 48 (40), 9416-9426, 2009
1402009
Oxidation of the albumin thiol to sulfenic acid and its implications in the intravascular compartment
L Turell, S Carballal, H Botti, R Radi, B Alvarez
Brazilian journal of medical and biological research 42, 305-311, 2009
1222009
Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening
J Neres, ML Brewer, L Ratier, H Botti, A Buschiazzo, PN Edwards, ...
Bioorganic & medicinal chemistry letters 19 (3), 589-596, 2009
852009
Sulfenic acid—a key intermediate in albumin thiol oxidation
L Turell, H Botti, S Carballal, R Radi, B Alvarez
Journal of Chromatography B 877 (28), 3384-3392, 2009
812009
Septic diaphragmatic dysfunction is prevented by Mn (III) porphyrin therapy and inducible nitric oxide synthase inhibition
N Nin, A Cassina, J Boggia, E Alfonso, H Botti, G Peluffo, A Trostchansky, ...
Intensive care medicine 30, 2271-2278, 2004
812004
Structural and enzymatic insights into the ATP binding and autophosphorylation mechanism of a sensor histidine kinase
F Trajtenberg, M Graña, N Ruétalo, H Botti, A Buschiazzo
Journal of biological chemistry 285 (32), 24892-24903, 2010
722010
Modulation of the reactivity of the thiol of human serum albumin and its sulfenic derivative by fatty acids
MJ Torres, L Turell, H Botti, L Antmann, S Carballal, G Ferrer-Sueta, ...
Archives of biochemistry and biophysics 521 (1-2), 102-110, 2012
702012
Peroxynitrite flux-mediated LDL oxidation is inhibited by manganese porphyrins in the presence of uric acid
A Trostchansky, G Ferrer-Sueta, C Batthyány, H Botti, I Batinić-Haberle, ...
Free Radical Biology and Medicine 35 (10), 1293-1300, 2003
692003
Formation of lipid-protein adducts in low-density lipoprotein by fluxes of peroxynitrite and its inhibition by nitric oxide
A Trostchansky, C Batthyány, H Botti, R Radi, A Denicola, H Rubbo
Archives of biochemistry and biophysics 395 (2), 225-232, 2001
672001
Peroxynitrite-mediated α-tocopherol oxidation in low-density lipoprotein: a mechanistic approach
H Botti, C Batthyány, A Trostchansky, R Radi, BA Freeman, H Rubbo
Free Radical Biology and Medicine 36 (2), 152-162, 2004
652004
Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation
F Trajtenberg, D Albanesi, N Ruétalo, H Botti, AE Mechaly, M Nieves, ...
MBio 5 (6), 10.1128/mbio. 02105-14, 2014
582014
Reactivity of peroxynitrite and nitric oxide with LDL
H Botti, A Trostchansky, C Batthyany, H Rubbo
Iubmb Life 57 (6), 407-412, 2005
452005
Design, synthesis, and biological characterization of potential antiatherogenic nitric oxide releasing tocopherol analogs
GV López, C Batthyány, F Blanco, H Botti, A Trostchansky, E Migliaro, ...
Bioorganic & medicinal chemistry 13 (20), 5787-5796, 2005
442005
Distance-Dependent Diffusion-Controlled Reaction of NO and O2•− at Chemical Equilibrium with ONOO
H Botti, MN Möller, D Steinmann, T Nauser, WH Koppenol, A Denicola, ...
The journal of physical chemistry B 114 (49), 16584-16593, 2010
422010
Nitric oxide inhibits prooxidant actions of uric acid during copper-mediated LDL oxidation
SM Sanguinetti, C Batthyány, A Trostchansky, H Botti, GI López, ...
Archives of biochemistry and biophysics 423 (2), 302-308, 2004
422004
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Artigos 1–20