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Šoltésová Prnová
Šoltésová Prnová
vedecký pracovník SAV
E-mail confirmado em savba.sk
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Novel quercetin derivatives: From redox properties to promising treatment of oxidative stress related diseases
P Zizkova, M Stefek, L Rackova, M Prnova, L Horakova
Chemico-Biological Interactions 265, 36-46, 2017
562017
2-Chloro-1, 4-naphthoquinone derivative of quercetin as an inhibitor of aldose reductase and anti-inflammatory agent
I Milackova, MS Prnova, M Majekova, R Sotnikova, M Stasko, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 30 (1), 107-113, 2015
532015
Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold
M Stefek, M Soltesova Prnova, M Majekova, C Rechlin, A Heine, G Klebe
Journal of Medicinal Chemistry 58 (6), 2649-2657, 2015
472015
A novel carboxymethylated mercaptotriazinoindole inhibitor of aldose reductase interferes with the polyol pathway in streptozotocin-induced diabetic rats
MS Prnova, J Ballekova, A Gajdosikova, A Gajdosik, M Stefek
Physiological Research 64 (4), 587, 2015
262015
Cornelian cherry fruit improves glycaemia and manifestations of diabetes in obese Zucker diabetic fatty rats
M Capcarova, A Kalafova, M Schwarzova, M Schneidgenova, K Svik, ...
Research in veterinary science 126, 118-123, 2019
242019
Development of novel oxotriazinoindole inhibitors of aldose reductase: isosteric sulfur/oxygen replacement in the thioxotriazinoindole cemtirestat markedly improved inhibition …
M Hlavac, L Kovacikova, MS Prnova, P Sramel, G Addová, M Májeková, ...
Journal of Medicinal Chemistry 63 (1), 369-381, 2019
222019
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl) phenol as a scaffold for improved membrane permeation
M Chatzopoulou, A Patsilinakos, T Vallianatou, MS Prnova, S Žakelj, ...
Bioorganic & Medicinal Chemistry 22 (7), 2194-2207, 2014
222014
Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat—another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ …
MS Prnova, L Kovacikova, K Svik, S Bezek, Z Elmazoğlu, C Karasu, ...
Naunyn-Schmiedeberg's Archives of Pharmacology 393, 651-661, 2020
212020
3-Mercapto-5H-1,2,4-Triazino[5,6-b]Indole-5-Acetic Acid (Cemtirestat) Alleviates Symptoms of Peripheral Diabetic Neuropathy in Zucker Diabetic Fatty (ZDF) Rats …
M Soltesova Prnova, K Svik, S Bezek, L Kovacikova, C Karasu, M Stefek
Neurochemical research 44, 1056-1064, 2019
212019
Chalcones and their pyrazine analogs: synthesis, inhibition of aldose reductase, antioxidant activity, and molecular docking study
M Kucerova-Chlupacova, M Dosedel, J Kunes, M Soltesova-Prnova, ...
Monatshefte für Chemie-Chemical Monthly 149, 921-929, 2018
212018
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives
MUM Siddique, A Thakur, D Shilkar, S Yasmin, D Halakova, L Kovacikova, ...
European journal of medicinal chemistry 223, 113630, 2021
192021
3′-O-(3-Chloropivaloyl) quercetin, α-glucosidase inhibitor with multi-targeted therapeutic potential in relation to diabetic complications
M Soltesova-Prnova, I Milackova, M Stefek
Chemical Papers 70 (11), 1439-1444, 2016
192016
Consumption of bee bread influences glycaemia and development of diabetes in obese spontaneous diabetic rats
M Capcarova, A Kalafova, M Schwarzova, M Schneidgenova, MS Prnova, ...
Biologia 75, 705-711, 2020
162020
Antioxidant action of 3-mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid, an efficient aldose reductase inhibitor, in a 1,1′-diphenyl-2-picrylhydrazyl assay and in the …
M Soltesova Prnova, J Ballekova, M Majekova, M Stefek
Redox Report 20 (6), 282-288, 2015
162015
Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
M Majekova, J Ballekova, M Prnova, M Stefek
Bioorganic & Medicinal Chemistry 25 (24), 6353-6360, 2017
142017
The consumption of sea buckthorn (Hippophae rhamnoides L.) effectively alleviates type 2 diabetes symptoms in spontaneous diabetic rats
R Dupak, J Hrnkova, N Simonova, J Kovac, E Ivanisova, A Kalafova, ...
Research in Veterinary Science 152, 261-269, 2022
132022
Development of novel indole-based bifunctional aldose reductase inhibitors/antioxidants as promising drugs for the treatment of diabetic complications
L Kovacikova, MS Prnova, M Majekova, A Bohac, C Karasu, M Stefek
Molecules 26 (10), 2867, 2021
122021
(4-Oxo-2-thioxothiazolidin-3-yl) acetic acids as potent and selective aldose reductase inhibitors
M Kucerova-Chlupacova, D Halakova, M Majekova, J Treml, M Stefek, ...
Chemico-Biological Interactions 332, 109286, 2020
112020
Combatting nitrosative stress and inflammation with novel substituted triazinoindole inhibitors of aldose reductase in PC12 cells exposed to 6-hydroxydopamine plus high glucose
Z Elmazoglu, MS Prnova, A Santamaria, M Stefek, C Karasu
Neurotoxicity Research 39, 210-226, 2021
102021
Antioxidant mechanisms in the neuroprotective action of cemtirestat: studies in chemical models, liposomes and rat brain cortical slices
MS Prnova, ON Medina-Campos, J Pedraza-Chaverri, AL Colín-González, ...
Neuroscience 443, 206-217, 2020
102020
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