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GRUBER, Christian W.
GRUBER, Christian W.
Associate Professor
E-mail confirmado em meduniwien.ac.at - Página inicial
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Natural products in drug discovery: advances and opportunities
AG Atanasov, SB Zotchev, VM Dirsch, CT Supuran
Nature reviews Drug discovery 20 (3), 200-216, 2021
34572021
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ...
Natural product reports 30 (1), 108-160, 2013
21602013
Protein disulfide isomerase: the structure of oxidative folding
CW Gruber, M Čemažar, B Heras, JL Martin, DJ Craik
Trends in biochemical sciences 31 (8), 455-464, 2006
4202006
Distribution and evolution of circular miniproteins in flowering plants
CW Gruber, AG Elliott, DC Ireland, PG Delprete, S Dessein, U Goransson, ...
The Plant Cell 20 (9), 2471-2483, 2008
3102008
Insecticidal plant cyclotides and related cystine knot toxins
CW Gruber, MA Anderson, DJ Craik
Toxicon 49 (4), 561-575, 2007
1652007
Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis
CK Wang, CW Gruber, M Cemazar, C Siatskas, P Tagore, N Payne, ...
ACS chemical biology 9 (1), 156-163, 2014
1622014
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design
J Koehbach, M O’Brien, M Muttenthaler, M Miazzo, M Akcan, AG Elliott, ...
Proceedings of the National Academy of Sciences 110 (52), 21183-21188, 2013
1622013
A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins
CW Gruber, M Cemazar, RJ Clark, T Horibe, RF Renda, MA Anderson, ...
Journal of Biological Chemistry 282 (28), 20435-20446, 2007
1602007
Uterotonic plants and their bioactive constituents
CW Gruber, M O'Brien
Planta medica 77 (03), 207-220, 2011
1472011
Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis
K Thell, R Hellinger, E Sahin, P Michenthaler, M Gold-Binder, T Haider, ...
Proceedings of the National Academy of Sciences 113 (15), 3960-3965, 2016
1432016
Peptide-based protease inhibitors from plants
R Hellinger, CW Gruber
Drug discovery today 24 (9), 1877-1889, 2019
1382019
Physiology of invertebrate oxytocin and vasopressin neuropeptides
CW Gruber
Experimental physiology 99 (1), 55-61, 2014
1352014
The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters
S Bulling, K Schicker, YW Zhang, T Steinkellner, T Stockner, CW Gruber, ...
Journal of Biological Chemistry 287 (22), 18524-18534, 2012
1312012
Immunosuppressive activity of an aqueous Viola tricolor herbal extract
R Hellinger, J Koehbach, H Fedchuk, B Sauer, R Huber, CW Gruber, ...
Journal of Ethnopharmacology 151 (1), 299-306, 2014
1282014
Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors
MF CW Gruber, M Muttenthaler
Current Pharmaceutical Design 16, 3071-88, 2010
1242010
Uterine contractility of plants used to facilitate childbirth in Nigerian ethnomedicine
AF Attah, M O'brien, J Koehbach, MA Sonibare, JO Moody, TJ Smith, ...
Journal of ethnopharmacology 143 (1), 377-382, 2012
1222012
Cyclotide discovery in Gentianales revisited—identification and characterization of cyclic cystine‐knot peptides and their phylogenetic distribution in Rubiaceae plants
J Koehbach, AF Attah, A Berger, R Hellinger, TM Kutchan, EJ Carpenter, ...
Peptide Science 100 (5), 438-452, 2013
1212013
Peptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining
R Hellinger, J Koehbach, DE Soltis, EJ Carpenter, GKS Wong, CW Gruber
Journal of proteome research 14 (11), 4851-4862, 2015
1102015
Do plant cyclotides have potential as immunosuppressant peptides?
C Gründemann, J Koehbach, R Huber, CW Gruber
Journal of natural products 75 (2), 167-174, 2012
1102012
Immunosuppressive peptides and their therapeutic applications
K Thell, R Hellinger, G Schabbauer, CW Gruber
Drug discovery today 19 (5), 645-653, 2014
1082014
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