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Yulong Xu
Yulong Xu
Massachusetts General Hospital, Harvard Medical School
E-mail confirmado em mgh.harvard.edu
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Magnetically recoverable nanoparticles: highly efficient catalysts for asymmetric transfer hydrogenation of aromatic ketones in aqueous medium
G Liu, H Gu, Y Sun, J Long, Y Xu, H Li
Advanced Synthesis & Catalysis 353 (8), 1317-1324, 2011
532011
Microwave-assisted synthesis of phenanthridines by radical insertion/cyclization of biphenyl isocyanides
Y Xu, Y Chen, W Li, Q Xie, L Shao
The Journal of Organic Chemistry 81 (18), 8426-8435, 2016
482016
Efficient and C2-selective arylation of indoles, benzofurans, and benzothiophenes with iodobenzenes in water at room temperature
Z Xu, Y Xu, H Lu, T Yang, X Lin, L Shao, F Ren
Tetrahedron 71 (18), 2616-2621, 2015
472015
An Ion‐Pair Immobilization Strategy in Rhodium‐Catalyzed Asymmetric Transfer Hydrogenation of Aromatic Ketones
Y Xu, T Cheng, J Long, K Liu, Q Qian, F Gao, G Liu, H Li
Advanced Synthesis & Catalysis 354 (17), 3250-3258, 2012
362012
Regioselective Access to 3-Aryl-1-aminoisoquinolines via Nickel (I)-Catalyzed C–C and C–N Cascade Coupling Reactions from the Substituted 2-(Cyanomethyl) benzonitriles
X Yang, H Yu, Y Xu, L Shao
The Journal of Organic Chemistry 83 (17), 9682-9695, 2018
242018
Microwave-assisted synthesis of hydroxyl-containing isoquinolines by metal-free radical cyclization of vinyl isocyanides with alcohols
D Xue, H Chen, Y Xu, H Yu, L Yu, W Li, Q Xie, L Shao
Organic & Biomolecular Chemistry 15 (47), 10044-10052, 2017
202017
The pharmacological heterogeneity of nepenthone analogs in conferring highly selective and potent κ-opioid agonistic activities
W Li, JD Long, YY Qian, Y Long, XJ Xu, YJ Wang, Q Shen, ZN Wang, ...
ACS Chemical Neuroscience 8 (4), 766-776, 2017
172017
Discovery of carbon-11 labeled sulfonamide derivative: A PET tracer for imaging brain NLRP3 inflammasome
Y Xu, Y Xu, H Blevins, Y Lan, Y Liu, G Yuan, R Striar, JS Zagaroli, ...
Bioorganic & medicinal chemistry letters 34, 127777, 2021
142021
Synthetic access to isoxazoline-functionalized isoquinolines via microwave-assisted iminoxyl radical-participated cascade cyclization of vinyl isocyanides
Y Xu, H Chen, W Li, Q Xie, L Yu, L Shao
Organic & Biomolecular Chemistry 16 (27), 4996-5005, 2018
142018
Molecular imaging of Alzheimer’s disease–related gamma-secretase in mice and nonhuman primates
Y Xu, C Wang, HY Wey, Y Liang, Z Chen, SH Choi, C Ran, KD Rynearson, ...
Journal of Experimental Medicine 217 (12), 2020
122020
Imaging assisted evaluation of antitumor efficacy of a new histone deacetylase inhibitor in the castration-resistant prostate cancer
Z Chen, X Wang, X Yang, Y Xu, Y Yang, H Wang, T Li, P Bai, G Yuan, ...
European Journal of Nuclear Medicine and Molecular Imaging 48, 53-66, 2021
112021
Discovery of novel 20S proteasome inhibitors by rational topology-based scaffold hopping of bortezomib
Y Xu, X Yang, Y Chen, H Chen, H Sun, W Li, Q Xie, L Yu, L Shao
Bioorganic & Medicinal Chemistry Letters 28 (12), 2148-2152, 2018
112018
A convenient aqueous copper-catalyzed synthesis of quinazolinones
Y Xu, Q Xie, W Li, H Sun, Y Wang, L Shao
Tetrahedron 71 (29), 4853-4858, 2015
92015
Identification of fluorinated (R)-(−)-aporphine derivatives as potent and selective ligands at serotonin 5-HT2C receptor
Y Xu, AW Sromek, JL Neumeyer
Bioorganic & Medicinal Chemistry Letters 29 (2), 230-233, 2019
82019
The NLRP3 inflammasome pathway: A review of mechanisms and inhibitors for the treatment of inflammatory diseases. Front Aging Neurosci 2022; 14: 879021
HM Blevins, Y Xu, S Biby, S Zhang
8
Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies
Y Xu, Y Xu, H Blevins, C Guo, S Biby, XY Wang, C Wang, S Zhang
European journal of medicinal chemistry 238, 114468, 2022
72022
Synthesis of 11C-labeled DNA polymerase-β inhibitor 5-methoxyflavone and PET/CT imaging thereof
Z Chen, X Wang, Y Xu, C Wang
Nuclear Medicine and Biology 78, 17-22, 2019
62019
Microwave‐Assisted Radical Insertion/Cyclization of Vinyl Isocyanides for the Synthesis of Multi‐Substituted Isoquinolines
Y Xu, H Chen, W Li, Q Xie, L Yu, L Shao
ChemistrySelect 2 (26), 8033-8038, 2017
62017
Synthesis and characterization of a new Positron emission tomography probe for orexin 2 receptors neuroimaging
P Bai, Y Liu, Y Xu, R Striar, G Yuan, S Afshar, AG Langan, AK Rattray, ...
Bioorganic chemistry 123, 105779, 2022
52022
Synthesis and Characterization of Carbon-11 Labeled Iloperidone for Imaging of α1-Adrenoceptor in Brain
Y Xu, Y Wang, H Wang, C Wang
Frontiers in Molecular Biosciences 7, 586327, 2020
42020
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