Lício Velloso
Lício Velloso
Professor of Medicine - University of Campinas
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Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
CT De Souza, EP Araujo, S Bordin, R Ashimine, RL Zollner, AC Boschero, ...
Endocrinology 146 (10), 4192-4199, 2005
10202005
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity
M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ...
Journal of Neuroscience 29 (2), 359-370, 2009
9202009
Endoplasmic reticulum stress, obesity and diabetes
M Cnop, F Foufelle, LA Velloso
Trends in molecular medicine 18 (1), 59-68, 2012
5642012
Cross-talk between the insulin and angiotensin signaling systems
LA Velloso, F Folli, XJ Sun, MF White, MJ Saad, CR Kahn
Proceedings of the National Academy of Sciences 93 (22), 12490-12495, 1996
4531996
High-fat diet induces apoptosis of hypothalamic neurons
JC Moraes, A Coope, J Morari, DE Cintra, EA Roman, JR Pauli, ...
PloS one 4 (4), e5045, 2009
4082009
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition
ER Ropelle, MB Flores, DE Cintra, GZ Rocha, JR Pauli, J Morari, ...
PLoS Biol 8 (8), e1000465, 2010
3742010
Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity
DE Cintra, ER Ropelle, JC Moraes, JR Pauli, J Morari, CT de Souza, ...
PloS one 7 (1), e30571, 2012
3392012
S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance
MA Carvalho-Filho, M Ueno, SM Hirabara, AB Seabra, JBC Carvalheira, ...
Diabetes 54 (4), 959-967, 2005
3032005
TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys
MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ...
Cell metabolism 18 (6), 831-843, 2013
2652013
Crosstalk between insulin and angiotensin II signalling systems
F Folli, MJA Saad, L Velloso, H Hansen, O Carandente, EP Feener, ...
Experimental and clinical endocrinology & diabetes 107 (02), 133-139, 1999
2061999
Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver
M Milanski, AP Arruda, A Coope, LM Ignacio-Souza, CE Nunez, ...
Diabetes 61 (6), 1455-1462, 2012
2002012
Reversal of diet‐induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS‐1 serine phosphorylation
ER Ropelle, JR Pauli, PO Prada, CT De Souza, PK Picardi, MC Faria, ...
The Journal of physiology 577 (3), 997-1007, 2006
1972006
GAD autoantibodies in IDDM, stiff-man syndrome, and autoimmune polyendocrine syndrome type I recognize different epitopes
E Björk, LA Velloso, O Kämpe, FA Karlsson
Diabetes 43 (1), 161-165, 1994
1951994
Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats
CR Carvalho, SL Brenelli, AC Silva, AL Nunes, LA Velloso, MJ Saad
Endocrinology 137 (1), 151-159, 1996
1941996
Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats
JBC Carvalheira, EB Ribeiro, EP Araujo, RB Guimaraes, MM Telles, ...
Diabetologia 46 (12), 1629-1640, 2003
1882003
Insulin modulates leptin-induced STAT3 activation in rat hypothalamus
JBC Carvalheira, RMP Siloto, I Ignacchitti, SL Brenelli, CRO Carvalho, ...
FEBS letters 500 (3), 119-124, 2001
1882001
Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet
R Barbuio, M Milanski, MB Bertolo, MJ Saad, LA Velloso
Journal of Endocrinology 194 (3), 539-550, 2007
1842007
TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation
LA Velloso, F Folli, MJ Saad
Endocrine reviews 36 (3), 245-271, 2015
1812015
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
DE Cintra, JR Pauli, EP Araújo, JC Moraes, CT de Souza, M Milanski, ...
Journal of hepatology 48 (4), 628-637, 2008
1802008
Altered hypothalamic function in diet-induced obesity
LA Velloso, MW Schwartz
International journal of obesity 35 (12), 1455-1465, 2011
1782011
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