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Minxian(Wallace) Wang
Minxian(Wallace) Wang
The Broad Institute of MIT and Harvard
E-mail confirmado em broadinstitute.org
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Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
AC Fahed, M Wang, JR Homburger, AP Patel, AG Bick, CL Neben, C Lai, ...
Nature communications 11 (1), 3635, 2020
3212020
Lp (a)(lipoprotein [a]) concentrations and incident atherosclerotic cardiovascular disease: new insights from a large national biobank
AP Patel, M Wang, JP Pirruccello, PT Ellinor, K Ng, S Kathiresan, ...
Arteriosclerosis, thrombosis, and vascular biology 41 (1), 465-474, 2021
2212021
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
KG Aragam, T Jiang, A Goel, S Kanoni, BN Wolford, DS Atri, EM Weeks, ...
Nature genetics 54 (12), 1803-1815, 2022
1892022
Association of habitual alcohol intake with risk of cardiovascular disease
KJ Biddinger, CA Emdin, ME Haas, M Wang, G Hindy, PT Ellinor, ...
JAMA network open 5 (3), e223849-e223849, 2022
1802022
Polygenic basis and biomedical consequences of telomere length variation
V Codd, Q Wang, E Allara, C Musicha, S Kaptoge, S Stoma, T Jiang, ...
Nature genetics 53 (10), 1425-1433, 2021
1692021
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy
JP Pirruccello, A Bick, M Wang, M Chaffin, S Friedman, J Yao, X Guo, ...
Nature communications 11 (1), 2254, 2020
1642020
Quantifying and understanding the higher risk of atherosclerotic cardiovascular disease among South Asian individuals: results from the UK Biobank prospective cohort study
AP Patel, M Wang, U Kartoun, K Ng, AV Khera
Circulation 144 (6), 410-422, 2021
862021
Association of rare pathogenic DNA variants for familial hypercholesterolemia, hereditary breast and ovarian cancer syndrome, and lynch syndrome with disease risk in adults …
AP Patel, M Wang, AC Fahed, H Mason-Suares, D Brockman, R Pelletier, ...
JAMA network open 3 (4), e203959-e203959, 2020
822020
Validation of a genome-wide polygenic score for coronary artery disease in South Asians
M Wang, R Menon, S Mishra, AP Patel, M Chaffin, D Tanneeru, ...
Journal of the American College of Cardiology 76 (6), 703-714, 2020
802020
Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch
D Feng, J Notbohm, A Benjamin, S He, M Wang, LH Ang, M Bantawa, ...
Proceedings of the National Academy of Sciences 115 (7), 1517-1522, 2018
612018
Machine learning enables new insights into genetic contributions to liver fat accumulation
ME Haas, JP Pirruccello, SN Friedman, M Wang, CA Emdin, VH Ajmera, ...
Cell genomics 1 (3), 2021
592021
UBD modifies APOL1-induced kidney disease risk
JY Zhang, M Wang, L Tian, G Genovese, P Yan, JG Wilson, R Thadhani, ...
Proceedings of the National Academy of Sciences 115 (13), 3446-3451, 2018
502018
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots
S Agrawal, M Wang, MDR Klarqvist, K Smith, J Shin, H Dashti, N Diamant, ...
Nature communications 13 (1), 3771, 2022
472022
Contributions of rare gene variants to familial and sporadic FSGS
M Wang, J Chun, G Genovese, AU Knob, A Benjamin, MS Wilkins, ...
Journal of the American Society of Nephrology 30 (9), 1625-1640, 2019
472019
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease
AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ...
Nature Medicine 29 (7), 1793-1803, 2023
352023
Rare genetic variants associated with sudden cardiac death in adults
AV Khera, H Mason-Suares, D Brockman, M Wang, MJ VanDenburgh, ...
Journal of the American College of Cardiology 74 (21), 2623-2634, 2019
352019
APOL1-associated kidney disease in Brazil
C Riella, TA Siemens, M Wang, RP Campos, TP Moraes, LV Riella, ...
Kidney international reports 4 (7), 923-929, 2019
302019
Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes
G Hindy, P Dornbos, MD Chaffin, DJ Liu, M Wang, MS Selvaraj, D Zhang, ...
The American Journal of Human Genetics 109 (1), 81-96, 2022
262022
Association of the interaction between familial hypercholesterolemia variants and adherence to a healthy lifestyle with risk of coronary artery disease
AC Fahed, M Wang, AP Patel, E Ajufo, DJ Maamari, KG Aragam, ...
JAMA network open 5 (3), e222687-e222687, 2022
252022
Detecting recent positive selection with high accuracy and reliability by conditional coalescent tree
M Wang, X Huang, R Li, H Xu, L Jin, Y He
Molecular biology and evolution 31 (11), 3068-3080, 2014
232014
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