Julia Joung
Julia Joung
Biological Engineering PhD candidate, Massachusetts Institute of Technology
E-mail confirmado em mit.edu
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
B Zetsche, JS Gootenberg, OO Abudayyeh, IM Slaymaker, KS Makarova, ...
Cell 163 (3), 759-771, 2015
21712015
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ...
Nature 517 (7536), 583-588, 2015
15562015
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ...
Science 353 (6299), 2016
7872016
Nucleic acid detection with CRISPR-Cas13a/C2c2
JS Gootenberg, OO Abudayyeh, JW Lee, P Essletzbichler, AJ Dy, J Joung, ...
Science 356 (6336), 438-442, 2017
6902017
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
WS Chung, LE Clarke, GX Wang, BK Stafford, A Sher, C Chakraborty, ...
Nature 504 (7480), 394-400, 2013
6182013
Discovery and functional characterization of diverse class 2 CRISPR-Cas systems
S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ...
Molecular cell 60 (3), 385-397, 2015
6122015
RNA editing with CRISPR-Cas13
DBT Cox, JS Gootenberg, OO Abudayyeh, B Franklin, MJ Kellner, J Joung, ...
Science 358 (6366), 1019-1027, 2017
5872017
RNA targeting with CRISPR–Cas13
OO Abudayyeh, JS Gootenberg, P Essletzbichler, S Han, J Joung, ...
Nature 550 (7675), 280-284, 2017
5792017
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
JS Gootenberg, OO Abudayyeh, MJ Kellner, J Joung, JJ Collins, F Zhang
Science 360 (6387), 439-444, 2018
4822018
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ...
Nature protocols 12 (4), 828-863, 2017
3092017
High-resolution interrogation of functional elements in the noncoding genome
NE Sanjana, J Wright, K Zheng, O Shalem, P Fontanillas, J Joung, ...
Science 353 (6307), 1545-1549, 2016
2042016
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ...
Nature 548 (7667), 343-346, 2017
1982017
Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
JE Dahlman, OO Abudayyeh, J Joung, JS Gootenberg, F Zhang, ...
Nature biotechnology 33 (11), 1159-1161, 2015
1552015
Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes
WS Chung, PB Verghese, C Chakraborty, J Joung, BT Hyman, JD Ulrich, ...
Proceedings of the National Academy of Sciences 113 (36), 10186-10191, 2016
1072016
A cytosine deaminase for programmable single-base RNA editing
OO Abudayyeh, JS Gootenberg, B Franklin, J Koob, MJ Kellner, A Ladha, ...
Science 365 (6451), 382-386, 2019
612019
Point-of-care testing for COVID-19 using SHERLOCK diagnostics
J Joung, A Ladha, M Saito, M Segel, R Bruneau, MW Huang, NG Kim, ...
medRxiv, 2020
352020
Novel crispr enzymes and systems
K Severinov, F Zhang, YI Wolf, S Shmakov, E Semenova, L Minakhin, ...
US Patent App. 15/482,603, 2017
112017
A 5-min RNA preparation method for COVID-19 detection with RT-qPCR
A Ladha, J Joung, O Abudayyeh, J Gootenberg, F Zhang
medRxiv, 2020
92020
Application of CRISPR genetic screens to investigate neurological diseases
RWL So, SW Chung, HHC Lau, JJ Watts, E Gaudette, ZAM Al-Azzawi, ...
Molecular neurodegeneration 14 (1), 1-16, 2019
72019
Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing
J Joung, A Ladha, M Saito, NG Kim, AE Woolley, M Segel, RPJ Barretto, ...
New England Journal of Medicine 383 (15), 1492-1494, 2020
62020
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