Molecular modeling and inhibition of phospholipase A2 by polyhydroxy phenolic compounds SL Da Silva, AK Calgarotto, V Maso, DCS Damico, P Baldasso, CL Veber, ... European Journal of Medicinal Chemistry 44 (1), 312-321, 2009 | 78 | 2009 |
Design, synthesis, biological activity and structure-activity relationship studies of chalcone derivatives as potential anti-Candida agents JT Andrade, FRS Santos, WG Lima, CDF Sousa, LSFM Oliveira, ... The Journal of antibiotics 71 (8), 702-712, 2018 | 48 | 2018 |
21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na, K-ATPase and epithelial tight junctions SC Rocha, MTC Pessoa, LDR Neves, SLG Alves, LM Silva, HL Santos, ... PLoS One 9 (10), e108776, 2014 | 40 | 2014 |
Questionário de Vivência Acadêmica: estudo de consistência interna do instrumento no contexto brasileiro AAA Santos, APP Noronha, CB Amaro, J Villar Questões do cotidiano universitário, 159-177, 2005 | 37 | 2005 |
Synthesis and evaluation of nitrostyrene derivative compounds, new snake venom phospholipase A2 inhibitors J Villar, FTD Lima, CL Veber, ARM Oliveira, AK Calgarotto, S Marangoni, ... Toxicon 51 (8), 1467-1478, 2008 | 35 | 2008 |
Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells GD Da Silva, MG Da Silva, EM Souza, A Barison, SC Simões, FP Varotti, ... Molecules 17 (9), 10331-10343, 2012 | 26 | 2012 |
Synthesis and biological evaluation of novel 3-alkylpyridine marine alkaloid analogs with promising anticancer activity AMMN Gonçalves, AB De Lima, MCS Barbosa, LF De Camargos, ... Marine drugs 12 (8), 4361-4378, 2014 | 23 | 2014 |
Insect pheromone synthesis in Brazil: an overview PHG Zarbin, JAFP Villar, AG Corrêa Journal of the Brazilian Chemical Society 18, 1100-1124, 2007 | 22 | 2007 |
An easy and versatile approach to the synthesis of chiral pheromone lactones via 4, 4-dimethyl-2-oxazoline derivatives PHG Zarbin, ARM Oliveira, F Simonelli, JAFP Villar, O Delay Jr Tetrahedron letters 45 (40), 7399-7400, 2004 | 22 | 2004 |
Selectivity analyses of γ-benzylidene digoxin derivatives to different Na, K-ATPase α isoforms: a molecular docking approach MTC Pessôa, SLG Alves, AG Taranto, JAFP Villar, G Blanco, LA Barbosa Journal of enzyme inhibition and medicinal chemistry 33 (1), 85-97, 2018 | 20 | 2018 |
Differences of lipid membrane modulation and oxidative stress by digoxin and 21-benzylidene digoxin LND Silva, MTC Pessoa, SLG Alves, J Venugopal, VF Cortes, HL Santos, ... Experimental cell research 359 (1), 291-298, 2017 | 18 | 2017 |
γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na, K-ATPase activity effect SLG Alves, N Paixão, LGR Ferreira, FRS Santos, LDR Neves, GC Oliveira, ... Bioorganic & Medicinal Chemistry 23 (15), 4397-4404, 2015 | 18 | 2015 |
21‑Benzylidene digoxin, a novel digoxin hemi-synthetic derivative, presents an anti-inflammatory activity through inhibition of edema, tumour necrosis factor alpha production … L Vieira, AA Saldanha, AM Moraes, FM de Oliveira, DO Lopes, ... International immunopharmacology 65, 174-181, 2018 | 17 | 2018 |
Molecular modeling of the inhibition of enzyme PLA2 from snake venom by dipyrone and 1‐phenyl‐3‐methyl‐5‐pyrazolone SL Da Silva, M Comar Jr, KMT Oliveira, JS Chaar, ERM Bezerra, ... International journal of quantum chemistry 108 (13), 2576-2585, 2008 | 16 | 2008 |
Involvement of Src signaling in the synergistic effect between cisplatin and digoxin on cancer cell viability DG Pereira, MAR Salgado, SC Rocha, HL Santos, JAFP Villar, ... Journal of cellular biochemistry 119 (4), 3352-3362, 2018 | 15 | 2018 |
Pharmacologic potential of new nitro-compounds as antimicrobial agents against nosocomial pathogens: design, synthesis, and in vitro effectiveness JT Andrade, SLG Alves, WG Lima, CDF Sousa, LF Carmo, NP De Sá, ... Folia microbiologica 65, 393-405, 2020 | 13 | 2020 |
21-Benzylidene digoxin decreases proliferation by inhibiting the EGFR/ERK signaling pathway and induces apoptosis in HeLa cells MTC Pessôa, JMM Valadares, SC Rocha, SC Silva, JP McDermott, ... Steroids 155, 108551, 2020 | 13 | 2020 |
Conjugated addition of bis (oxazolinyl) zinc to substituted 2-nitrovinyl benzenes: an alternative synthesis of (±)-Rolipram ARM Oliveira, JAFP Villar, F Simonelli, RA Gariani, CL Wosch, ... Tetrahedron letters 48 (8), 1507-1509, 2007 | 13 | 2007 |
Evaluation of neuroprotective activity of digoxin and semisynthetic derivatives against partial chemical ischemia B de Souza Gonçalves, JM de Moura Valadares, SLG Alves, SC Silva, ... Journal of Cellular Biochemistry 120 (10), 17108-17122, 2019 | 12 | 2019 |
Synthesis and in vitro evaluation of novel triazole/azide chalcones FCG Evangelista, MO Bandeira, GD Silva, MG Silva, SN Andrade, ... Medicinal Chemistry Research 26, 27-43, 2017 | 11 | 2017 |