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José Augusto Ferreira Perez Villar
José Augusto Ferreira Perez Villar
E-mail confirmado em ufsj.edu.br
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Molecular modeling and inhibition of phospholipase A2 by polyhydroxy phenolic compounds
SL Da Silva, AK Calgarotto, V Maso, DCS Damico, P Baldasso, CL Veber, ...
European Journal of Medicinal Chemistry 44 (1), 312-321, 2009
782009
Design, synthesis, biological activity and structure-activity relationship studies of chalcone derivatives as potential anti-Candida agents
JT Andrade, FRS Santos, WG Lima, CDF Sousa, LSFM Oliveira, ...
The Journal of antibiotics 71 (8), 702-712, 2018
482018
21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na, K-ATPase and epithelial tight junctions
SC Rocha, MTC Pessoa, LDR Neves, SLG Alves, LM Silva, HL Santos, ...
PLoS One 9 (10), e108776, 2014
402014
Questionário de Vivência Acadêmica: estudo de consistência interna do instrumento no contexto brasileiro
AAA Santos, APP Noronha, CB Amaro, J Villar
Questões do cotidiano universitário, 159-177, 2005
372005
Synthesis and evaluation of nitrostyrene derivative compounds, new snake venom phospholipase A2 inhibitors
J Villar, FTD Lima, CL Veber, ARM Oliveira, AK Calgarotto, S Marangoni, ...
Toxicon 51 (8), 1467-1478, 2008
352008
Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells
GD Da Silva, MG Da Silva, EM Souza, A Barison, SC Simões, FP Varotti, ...
Molecules 17 (9), 10331-10343, 2012
262012
Synthesis and biological evaluation of novel 3-alkylpyridine marine alkaloid analogs with promising anticancer activity
AMMN Gonçalves, AB De Lima, MCS Barbosa, LF De Camargos, ...
Marine drugs 12 (8), 4361-4378, 2014
232014
Insect pheromone synthesis in Brazil: an overview
PHG Zarbin, JAFP Villar, AG Corrêa
Journal of the Brazilian Chemical Society 18, 1100-1124, 2007
222007
An easy and versatile approach to the synthesis of chiral pheromone lactones via 4, 4-dimethyl-2-oxazoline derivatives
PHG Zarbin, ARM Oliveira, F Simonelli, JAFP Villar, O Delay Jr
Tetrahedron letters 45 (40), 7399-7400, 2004
222004
Selectivity analyses of γ-benzylidene digoxin derivatives to different Na, K-ATPase α isoforms: a molecular docking approach
MTC Pessôa, SLG Alves, AG Taranto, JAFP Villar, G Blanco, LA Barbosa
Journal of enzyme inhibition and medicinal chemistry 33 (1), 85-97, 2018
202018
Differences of lipid membrane modulation and oxidative stress by digoxin and 21-benzylidene digoxin
LND Silva, MTC Pessoa, SLG Alves, J Venugopal, VF Cortes, HL Santos, ...
Experimental cell research 359 (1), 291-298, 2017
182017
γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na, K-ATPase activity effect
SLG Alves, N Paixão, LGR Ferreira, FRS Santos, LDR Neves, GC Oliveira, ...
Bioorganic & Medicinal Chemistry 23 (15), 4397-4404, 2015
182015
21‑Benzylidene digoxin, a novel digoxin hemi-synthetic derivative, presents an anti-inflammatory activity through inhibition of edema, tumour necrosis factor alpha production …
L Vieira, AA Saldanha, AM Moraes, FM de Oliveira, DO Lopes, ...
International immunopharmacology 65, 174-181, 2018
172018
Molecular modeling of the inhibition of enzyme PLA2 from snake venom by dipyrone and 1‐phenyl‐3‐methyl‐5‐pyrazolone
SL Da Silva, M Comar Jr, KMT Oliveira, JS Chaar, ERM Bezerra, ...
International journal of quantum chemistry 108 (13), 2576-2585, 2008
162008
Involvement of Src signaling in the synergistic effect between cisplatin and digoxin on cancer cell viability
DG Pereira, MAR Salgado, SC Rocha, HL Santos, JAFP Villar, ...
Journal of cellular biochemistry 119 (4), 3352-3362, 2018
152018
Pharmacologic potential of new nitro-compounds as antimicrobial agents against nosocomial pathogens: design, synthesis, and in vitro effectiveness
JT Andrade, SLG Alves, WG Lima, CDF Sousa, LF Carmo, NP De Sá, ...
Folia microbiologica 65, 393-405, 2020
132020
21-Benzylidene digoxin decreases proliferation by inhibiting the EGFR/ERK signaling pathway and induces apoptosis in HeLa cells
MTC Pessôa, JMM Valadares, SC Rocha, SC Silva, JP McDermott, ...
Steroids 155, 108551, 2020
132020
Conjugated addition of bis (oxazolinyl) zinc to substituted 2-nitrovinyl benzenes: an alternative synthesis of (±)-Rolipram
ARM Oliveira, JAFP Villar, F Simonelli, RA Gariani, CL Wosch, ...
Tetrahedron letters 48 (8), 1507-1509, 2007
132007
Evaluation of neuroprotective activity of digoxin and semisynthetic derivatives against partial chemical ischemia
B de Souza Gonçalves, JM de Moura Valadares, SLG Alves, SC Silva, ...
Journal of Cellular Biochemistry 120 (10), 17108-17122, 2019
122019
Synthesis and in vitro evaluation of novel triazole/azide chalcones
FCG Evangelista, MO Bandeira, GD Silva, MG Silva, SN Andrade, ...
Medicinal Chemistry Research 26, 27-43, 2017
112017
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