| The cystic fibrosis-causing mutation ΔF508 affects multiple steps in cystic fibrosis transmembrane conductance regulator biogenesis PH Thibodeau, JM Richardson, W Wang, L Millen, J Watson, JL Mendoza, ... Journal of Biological Chemistry 285 (46), 35825-35835, 2010 | 200 | 2010 |
| A comparison and chemometric analysis of several molecular mechanics force fields and parameter sets applied to carbohydrates S Pérez, A Imberty, SB Engelsen, J Gruza, K Mazeau, J Jimenez-Barbero, ... Carbohydrate Research 314 (3-4), 141-155, 1998 | 192 | 1998 |
| Docking studies on DNA intercalators Y Gilad, H Senderowitz Journal of chemical information and modeling 54 (1), 96-107, 2014 | 152 | 2014 |
| A smart Monte Carlo technique for free energy simulations of multiconformational molecules. Direct calculations of the conformational populations of organic molecules H Senderowitz, F Guarnieri, WC Still Journal of the American Chemical Society 117 (31), 8211-8219, 1995 | 137 | 1995 |
| Carbohydrates: united atom AMBER* parameterization of pyranoses and simulations yielding anomeric free energies H Senderowitz, C Parish, WC Still Journal of the American Chemical Society 118 (8), 2078-2086, 1996 | 134 | 1996 |
| Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening O Kalid, M Mense, S Fischman, A Shitrit, H Bihler, E Ben-Zeev, N Schutz, ... Journal of computer-aided molecular design 24, 971-991, 2010 | 111 | 2010 |
| Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives E Meltzer-Mats, G Babai-Shani, L Pasternak, N Uritsky, T Getter, O Viskind, ... Journal of medicinal chemistry 56 (13), 5335-5350, 2013 | 95 | 2013 |
| Plant phenolic volatiles inhibit quorum sensing in pectobacteria and reduce their virulence by potential binding to ExpI and ExpR proteins JR Joshi, N Khazanov, H Senderowitz, S Burdman, A Lipsky, I Yedidia Scientific Reports 6 (1), 38126, 2016 | 92 | 2016 |
| A quantum mechanically derived all-atom force field for pyranose oligosaccharides. AMBER* parameters and free energy simulations H Senderowitz, WC Still The Journal of Organic Chemistry 62 (5), 1427-1438, 1997 | 77 | 1997 |
| Synthesis, biological studies and molecular dynamics of new anticancer RGD-based peptide conjugates for targeted drug delivery Y Gilad, E Noy, H Senderowitz, A Albeck, MA Firer, G Gellerman Bioorganic & medicinal chemistry 24 (2), 294-303, 2016 | 58 | 2016 |
| Dual‐drug RGD conjugates provide enhanced cytotoxicity to melanoma and non‐small lung cancer cells Y Gilad, E Noy, H Senderowitz, A Albeck, MA Firer, G Gellerman Peptide Science 106 (2), 160-171, 2016 | 57 | 2016 |
| Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator RP Hudson, PA Chong, II Protasevich, R Vernon, E Noy, H Bihler, JL An, ... Journal of Biological Chemistry 287 (34), 28480-28494, 2012 | 57 | 2012 |
| Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5′-(α or γ)-thio-(α, β-or β, γ)-methylenetriphosphate scaffold Y Nadel, J Lecka, Y Gilad, G Ben-David, D Förster, G Reiser, ... Journal of medicinal chemistry 57 (11), 4677-4691, 2014 | 54 | 2014 |
| Exploring the conformational space of cyclic peptides by a stochastic search method A Rayan, H Senderowitz, A Goldblum Journal of Molecular Graphics and Modelling 22 (5), 319-333, 2004 | 54 | 2004 |
| Diagnostic structural criteria for the anomeric effect in carbohydrates and inferences of general significance on their scope and limitations L Schleifer, H Senderowitz, P Aped, E Tartakovsky, B Fuchs Carbohydrate research 206 (1), 21-39, 1990 | 53 | 1990 |
| Data Mining and Machine Learning Tools for Combinatorial Material Science of All‐Oxide Photovoltaic Cells A Yosipof, OE Nahum, AY Anderson, HN Barad, A Zaban, H Senderowitz Molecular informatics 34 (6‐7), 367-379, 2015 | 49 | 2015 |
| Nonhydrolyzable ATP analogues as selective inhibitors of human NPP1: a combined computational/experimental study J Lecka, G Ben-David, L Simhaev, S Eliahu, J Oscar Jr, P Luyindula, ... Journal of Medicinal Chemistry 56 (21), 8308-8320, 2013 | 47 | 2013 |
| New supramolecular host systems. 2. 1, 3, 5, 7-tetraoxadecalin, 1, 2-dimethoxyethane and the Gauche effect reappraised. Theory vs. experiment. H Senderowitz, L Golender, B Fuchs Tetrahedron 50 (32), 9707-9728, 1994 | 47 | 1994 |
| A novel substrate mimetic inhibitor of PKB/Akt inhibits prostate cancer tumor growth in mice by blocking the PKB pathway P Litman, O Ohne, S Ben-Yaakov, L Shemesh-Darvish, T Yechezkel, ... Biochemistry 46 (16), 4716-4724, 2007 | 44 | 2007 |
| Guaiacol as a drug candidate for treating adult polyglucosan body disease O Kakhlon, I Ferreira, LJ Solmesky, N Khazanov, A Lossos, R Alvarez, ... JCI insight 3 (17), 2018 | 41 | 2018 |
