Omar O. Abudayyeh
Omar O. Abudayyeh
McGovern Fellow, MIT
E-mail confirmado em mit.edu - Página inicial
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
B Zetsche, JS Gootenberg, OO Abudayyeh, IM Slaymaker, KS Makarova, ...
Cell 163 (3), 759-771, 2015
21752015
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ...
Nature 517 (7536), 583-588, 2015
15562015
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ...
Science 353 (6299), 2016
7872016
Nucleic acid detection with CRISPR-Cas13a/C2c2
JS Gootenberg, OO Abudayyeh, JW Lee, P Essletzbichler, AJ Dy, J Joung, ...
Science 356 (6336), 438-442, 2017
6902017
Discovery and functional characterization of diverse class 2 CRISPR-Cas systems
S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ...
Molecular cell 60 (3), 385-397, 2015
6122015
RNA editing with CRISPR-Cas13
DBT Cox, JS Gootenberg, OO Abudayyeh, B Franklin, MJ Kellner, J Joung, ...
Science 358 (6366), 1019-1027, 2017
5872017
RNA targeting with CRISPR–Cas13
OO Abudayyeh, JS Gootenberg, P Essletzbichler, S Han, J Joung, ...
Nature 550 (7675), 280-284, 2017
5792017
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
JS Gootenberg, OO Abudayyeh, MJ Kellner, J Joung, JJ Collins, F Zhang
Science 360 (6387), 439-444, 2018
4822018
Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ...
Nature biotechnology 35 (1), 31-34, 2017
4252017
Diversity and evolution of class 2 CRISPR–Cas systems
S Shmakov, A Smargon, D Scott, D Cox, N Pyzocha, W Yan, ...
Nature reviews microbiology 15 (3), 169-182, 2017
4192017
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors
DJ Konieczkowski, CM Johannessen, O Abudayyeh, JW Kim, ZA Cooper, ...
Cancer discovery 4 (7), 816-827, 2014
3452014
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ...
Nature protocols 12 (4), 828-863, 2017
3092017
Engineered CRISPR-Cas9 nuclease with expanded targeting space
H Nishimasu, X Shi, S Ishiguro, L Gao, S Hirano, S Okazaki, T Noda, ...
Science 361 (6408), 1259-1262, 2018
2742018
Field-deployable viral diagnostics using CRISPR-Cas13
C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh, HC Metsky, ...
Science 360 (6387), 444-448, 2018
2602018
Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28
AA Smargon, DBT Cox, NK Pyzocha, K Zheng, IM Slaymaker, ...
Molecular cell 65 (4), 618-630. e7, 2017
2362017
Structure and engineering of Francisella novicida Cas9
H Hirano, JS Gootenberg, T Horii, OO Abudayyeh, M Kimura, PD Hsu, ...
Cell 164 (5), 950-961, 2016
2032016
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ...
Nature 548 (7667), 343-346, 2017
1982017
Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
JE Dahlman, OO Abudayyeh, J Joung, JS Gootenberg, F Zhang, ...
Nature biotechnology 33 (11), 1159-1161, 2015
1562015
Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease
GA Kwong, G Von Maltzahn, G Murugappan, O Abudayyeh, S Mo, ...
Nature biotechnology 31 (1), 63-70, 2013
1522013
CRISPR enzymes and systems
F Zhang, B Zetsche, I Slaymaker, J Gootenberg, OO Abudayyeh
US Patent 9,790,490, 2017
1412017
O sistema não pode executar a operação agora. Tente novamente mais tarde.
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