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Pascale Lacor
Pascale Lacor
Northwestern University / Avid Radiopharmaceuticals
E-mail confirmado em avidrp.com
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Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
PN Lacor, MC Buniel, PW Furlow, AS Clemente, PT Velasco, M Wood, ...
Journal of Neuroscience 27 (4), 796-807, 2007
15032007
Alzheimer's disease-affected brain: presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss
Y Gong, L Chang, KL Viola, PN Lacor, MP Lambert, CE Finch, GA Krafft, ...
Proceedings of the National Academy of Sciences 100 (18), 10417-10422, 2003
14172003
Synaptic targeting by Alzheimer's-related amyloid β oligomers
PN Lacor, MC Buniel, L Chang, SJ Fernandez, Y Gong, KL Viola, ...
Journal of Neuroscience 24 (45), 10191-10200, 2004
12432004
Self-assembly of Aβ1-42 into globular neurotoxins
BA Chromy, RJ Nowak, MP Lambert, KL Viola, L Chang, PT Velasco, ...
Biochemistry 42 (44), 12749-12760, 2003
6822003
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
FG De Felice, D Wu, MP Lambert, SJ Fernandez, PT Velasco, PN Lacor, ...
Neurobiology of aging 29 (9), 1334-1347, 2008
5982008
Deleterious effects of amyloid β oligomers acting as an extracellular scaffold for mGluR5
M Renner, PN Lacor, PT Velasco, J Xu, A Contractor, WL Klein, A Triller
Neuron 66 (5), 739-754, 2010
5442010
Monoclonal antibodies that target pathological assemblies of Aβ
MP Lambert, PT Velasco, L Chang, KL Viola, S Fernandez, PN Lacor, ...
Journal of neurochemistry 100 (1), 23-35, 2007
4332007
Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells
NR Smalheiser, E Costa, A Guidotti, F Impagnatiello, J Auta, P Lacor, ...
Proceedings of the National Academy of Sciences 97 (3), 1281-1286, 2000
1972000
Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology
I Lauritzen, R Pardossi-Piquard, A Bourgeois, S Pagnotta, MG Biferi, ...
Acta neuropathologica 132, 257-276, 2016
1882016
Progesterone synthesis and myelin formation in peripheral nerves
M Schumacher, R Guennoun, G Mercier, F Désarnaud, P Lacor, ...
Brain research reviews 37 (1-3), 343-359, 2001
1872001
Aβ oligomer-induced synapse degeneration in Alzheimer’s disease
KC Wilcox, PN Lacor, J Pitt, WL Klein
Cellular and molecular neurobiology 31, 939-948, 2011
1862011
Stimulation of neurogenesis and synaptogenesis by bilobalide and quercetin via common final pathway in hippocampal neurons
F Tchantchou, PN Lacor, Z Cao, L Lao, Y Hou, C Cui, WL Klein, Y Luo
Journal of Alzheimer's disease 18 (4), 787-798, 2009
1822009
Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease
KL Viola, J Sbarboro, R Sureka, M De, MA Bicca, J Wang, S Vasavada, ...
Nature nanotechnology 10 (1), 91-98, 2015
1802015
Alzheimer's-associated Aβ oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal
J Pitt, W Roth, P Lacor, AB Smith III, M Blankenship, P Velasco, ...
Toxicology and applied pharmacology 240 (2), 189-197, 2009
1742009
Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric Aβ
WQ Zhao, PN Lacor, H Chen, MP Lambert, MJ Quon, GA Krafft, WL Klein
Journal of Biological Chemistry 284 (28), 18742-18753, 2009
1732009
Reelin function in neural stem cell biology
HM Kim, T Qu, V Kriho, P Lacor, N Smalheiser, GD Pappas, A Guidotti, ...
Proceedings of the National Academy of Sciences 99 (6), 4020-4025, 2002
1532002
Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer’s brains
K Ando, JP Brion, V Stygelbout, V Suain, M Authelet, R Dedecker, ...
Acta neuropathologica 125, 861-878, 2013
1432013
Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity
F Bao, L Wicklund, PN Lacor, WL Klein, A Nordberg, A Marutle
Neurobiology of aging 33 (4), 825. e1-825. e13, 2012
1392012
Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in …
P Lacor, P Gandolfo, MC Tonon, E Brault, I Dalibert, M Schumacher, ...
Brain research 815 (1), 70-80, 1999
1381999
Reelin secretion from glutamatergic neurons in culture is independent from neurotransmitter regulation
PN Lacor, DR Grayson, J Auta, I Sugaya, E Costa, A Guidotti
Proceedings of the National Academy of Sciences 97 (7), 3556-3561, 2000
1302000
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