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Eyal Gottlieb
Eyal Gottlieb
The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology
E-mail confirmado em technion.ac.il - Página inicial
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
31922018
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
L Galluzzi, I Vitale, JM Abrams, ES Alnemri, EH Baehrecke, ...
Cell Death & Differentiation 19 (1), 107-120, 2012
28082012
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ...
Nature 496 (7444), 238-242, 2013
25612013
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
K Bensaad, A Tsuruta, MA Selak, MNC Vidal, K Nakano, R Bartrons, ...
Cell 126 (1), 107-120, 2006
21712006
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
MA Selak, SM Armour, ED MacKenzie, H Boulahbel, DG Watson, ...
Cancer cell 7 (1), 77-85, 2005
20492005
Targeting metabolic transformation for cancer therapy
DA Tennant, RV Durán, E Gottlieb
Nature reviews cancer 10 (4), 267-277, 2010
11682010
Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages
EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ...
Cell 167 (2), 457-470. e13, 2016
11482016
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
ODK Maddocks, CR Berkers, SM Mason, L Zheng, K Blyth, E Gottlieb, ...
Nature 493 (7433), 542-546, 2013
7892013
Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer
A King, MA Selak, E Gottlieb
Oncogene 25 (34), 4675-4682, 2006
7752006
Mitochondrial tumour suppressors: a genetic and biochemical update
E Gottlieb, IPM Tomlinson
Nature Reviews Cancer 5 (11), 857-866, 2005
7172005
Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis
E Gottlieb, SM Armour, MH Harris, CB Thompson
Cell Death & Differentiation 10 (6), 709-717, 2003
6642003
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
M Morita, SP Gravel, V Chénard, K Sikström, L Zheng, T Alain, V Gandin, ...
Cell metabolism 18 (5), 698-711, 2013
6502013
p53 status determines the role of autophagy in pancreatic tumour development
MT Rosenfeldt, J O’Prey, JP Morton, C Nixon, G MacKay, A Mrowinska, ...
Nature 504 (7479), 296-300, 2013
6372013
Glutaminolysis activates Rag-mTORC1 signaling
RV Durán, W Oppliger, AM Robitaille, L Heiserich, R Skendaj, E Gottlieb, ...
Molecular cell 47 (3), 349-358, 2012
6192012
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
B Chaneton, P Hillmann, L Zheng, ACL Martin, ODK Maddocks, ...
Nature 491 (7424), 458-462, 2012
5512012
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ...
Cancer cell 27 (1), 57-71, 2015
5452015
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
J Kaplon, L Zheng, K Meissl, B Chaneton, VA Selivanov, G Mackay, ...
Nature 498 (7452), 109-112, 2013
5362013
Predicting selective drug targets in cancer through metabolic networks
O Folger, L Jerby, C Frezza, E Gottlieb, E Ruppin, T Shlomi
Molecular systems biology 7 (1), 501, 2011
5322011
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
4882015
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
C Frezza, L Zheng, O Folger, KN Rajagopalan, ED MacKenzie, L Jerby, ...
Nature 477 (7363), 225-228, 2011
4882011
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