| Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ... Nature 515 (7527), 431-435, 2014 | 2411 | 2014 |
| Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ... Cell 167 (2), 457-470. e13, 2016 | 1678 | 2016 |
| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 1258 | 2018 |
| Serine is an essential metabolite for effector T cell expansion EH Ma, G Bantug, T Griss, S Condotta, RM Johnson, B Samborska, ... Cell metabolism 25 (2), 345-357, 2017 | 557 | 2017 |
| Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ... Nature 537 (7621), 544-547, 2016 | 526 | 2016 |
| Effect of cooking methods on fatty acids, conjugated isomers of linoleic acid and nutritional quality of beef intramuscular fat CMM Alfaia, SP Alves, AF Lopes, MJE Fernandes, ASH Costa, ... Meat Science 84 (4), 769-777, 2010 | 272 | 2010 |
| Effect of the feeding system on intramuscular fatty acids and conjugated linoleic acid isomers of beef cattle, with emphasis on their nutritional value and discriminatory ability CPM Alfaia, SP Alves, SIV Martins, ASH Costa, CMGA Fontes, ... Food Chemistry 114 (3), 939-946, 2009 | 270 | 2009 |
| Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo PA Gammage, C Viscomi, ML Simard, ASH Costa, E Gaude, CA Powell, ... Nature medicine 24 (11), 1691-1695, 2018 | 259 | 2018 |
| Macrophage-derived extracellular succinate licenses neural stem cells to suppress chronic neuroinflammation L Peruzzotti-Jametti, JD Bernstock, N Vicario, ASH Costa, CK Kwok, ... Cell stem cell 22 (3), 355-368. e13, 2018 | 240 | 2018 |
| Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications MJ Koziol, CR Bradshaw, GE Allen, ASH Costa, C Frezza, JB Gurdon Nature structural & molecular biology 23 (1), 24-30, 2016 | 238 | 2016 |
| Cell surface proteomic map of HIV infection reveals antagonism of amino acid metabolism by Vpu and Nef NJ Matheson, J Sumner, K Wals, R Rapiteanu, MP Weekes, R Vigan, ... Cell host & microbe 18 (4), 409-423, 2015 | 184 | 2015 |
| Mitochondria-endoplasmic reticulum contact sites function as immunometabolic hubs that orchestrate the rapid recall response of memory CD8+ T cells GR Bantug, M Fischer, J Grählert, ML Balmer, G Unterstab, L Develioglu, ... Immunity 48 (3), 542-555. e6, 2018 | 149 | 2018 |
| Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition P Gallipoli, G Giotopoulos, K Tzelepis, ASH Costa, S Vohra, ... Blood, The Journal of the American Society of Hematology 131 (15), 1639-1653, 2018 | 147 | 2018 |
| Bone marrow mesenchymal stem cells support acute myeloid leukemia bioenergetics and enhance antioxidant defense and escape from chemotherapy D Forte, M García-Fernández, A Sanchez-Aguilera, V Stavropoulou, ... Cell metabolism 32 (5), 829-843. e9, 2020 | 146 | 2020 |
| Mitochondrial protein lipoylation and the 2-oxoglutarate dehydrogenase complex controls HIF1α stability in aerobic conditions SP Burr, ASH Costa, GL Grice, RT Timms, IT Lobb, P Freisinger, RB Dodd, ... Cell metabolism 24 (5), 740-752, 2016 | 131 | 2016 |
| Extracellular vesicles are independent metabolic units with asparaginase activity N Iraci, E Gaude, T Leonardi, ASH Costa, C Cossetti, L Peruzzotti-Jametti, ... Nature chemical biology 13 (9), 951-955, 2017 | 127 | 2017 |
| Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation JL Martin, ASH Costa, AV Gruszczyk, TE Beach, FM Allen, HA Prag, ... Nature metabolism 1 (10), 966-974, 2019 | 118 | 2019 |
| Cancer associated fibroblast FAK regulates malignant cell metabolism F Demircioglu, J Wang, J Candido, ASH Costa, P Casado, ... Nature communications 11 (1), 1290, 2020 | 108 | 2020 |
| Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses A Dugourd, C Kuppe, M Sciacovelli, E Gjerga, A Gabor, KB Emdal, ... Molecular Systems Biology 17 (1), e9730, 2021 | 106 | 2021 |
| Acute iron deprivation reprograms human macrophage metabolism and reduces inflammation in vivo M Pereira, TD Chen, N Buang, A Olona, JH Ko, M Prendecki, ASH Costa, ... Cell reports 28 (2), 498-511. e5, 2019 | 92 | 2019 |
Christian FrezzaCECAD, University of CologneE-mail confirmado em uni-koeln.de
