Seguir
Stewart N. Loh
Stewart N. Loh
Professor of Biochemistry, SUNY Upstate Medical University
E-mail confirmado em upstate.edu
Título
Citado por
Citado por
Ano
The energetics of hydrogen bonds in model systems: Implications for enzymatic catalysis
S Shan, S Loh, D Herschlag
Science 272 (5258), 97-101, 1996
3181996
Structure, function, and aggregation of the zinc-free form of the p53 DNA binding domain
JS Butler, SN Loh
Biochemistry 42 (8), 2396-2403, 2003
2112003
Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy
CA Royer, AP Hinck, SN Loh, KE Prehoda, X Peng, J Jonas, JL Markley
Biochemistry 32 (19), 5222-5232, 1993
1681993
Structure and stability of a second molten globule intermediate in the apomyoglobin folding pathway.
SN Loh, MS Kay, RL Baldwin
Proceedings of the National Academy of Sciences 92 (12), 5446-5450, 1995
1661995
EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction
J Zhao, A Blayney, X Liu, L Gandy, W Jin, L Yan, JH Ha, AJ Canning, ...
Nature communications 12 (1), 986, 2021
1552021
Protein conformational switches: from nature to design
JH Ha, SN Loh
Chemistry–A European Journal 18 (26), 7984-7999, 2012
1482012
The missing zinc: p53 misfolding and cancer
SN Loh
Metallomics 2 (7), 442-449, 2010
1412010
Hydrogen bonding in proteins as studied by amide hydrogen D/H fractionation factors: application to staphylococcal nuclease
SN Loh, JL Markley
Biochemistry 33 (4), 1029-1036, 1994
1321994
Solvent effects on the energetics of prolyl peptide bond isomerization
ES Eberhardt, SN Loh, AP Hinck, RT Raines
Journal of the American Chemical Society 114 (13), 5437-5439, 1992
1291992
Hydrogen exchange in unligated and ligated staphylococcal nuclease
SN Loh, KE Prehoda, J Wang, JL Markley
Biochemistry 32 (41), 11022-11028, 1993
1211993
Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism
X Yu, AR Blanden, S Narayanan, L Jayakumar, D Lubin, D Augeri, ...
Oncotarget 5 (19), 8879, 2014
1092014
Allosteric switching by mutually exclusive folding of protein domains
TL Radley, AI Markowska, BT Bettinger, JH Ha, SN Loh
Journal of molecular biology 332 (3), 529-536, 2003
1072003
Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer
AR Blanden, X Yu, SN Loh, AJ Levine, DR Carpizo
Drug discovery today 20 (11), 1391-1397, 2015
932015
Dynamics of equilibrium structural fluctuations of apomyoglobin measured by fluorescence correlation spectroscopy
H Chen, E Rhoades, JS Butler, SN Loh, WW Webb
Proceedings of the National Academy of Sciences 104 (25), 10459-10464, 2007
932007
Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore
AR Blanden, X Yu, AJ Wolfe, JA Gilleran, DJ Augeri, RS O’Dell, EC Olson, ...
Molecular pharmacology 87 (5), 825-831, 2015
862015
Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients
MR Woodford, RA Sager, E Marris, DM Dunn, AR Blanden, RL Murphy, ...
The EMBO journal 36 (24), 3650-3665, 2017
792017
Changes in side chain packing during apomyoglobin folding characterized by pulsed thiol-disulfide exchange
JH Ha, SN Loh
Nature structural biology 5 (8), 730-737, 1998
641998
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
MR Woodford, DM Dunn, AR Blanden, D Capriotti, D Loiselle, ...
Nature communications 7 (1), 12037, 2016
622016
Zn2+-Dependent Misfolding of the p53 DNA Binding Domain
JS Butler, SN Loh
Biochemistry 46 (10), 2630-2639, 2007
622007
Solution studies of staphylococcal nuclease H124L. 2. 1H, 13C, and 15N chemical shift assignments for the unligated enzyme and analysis of chemical shift changes that accompany …
JF Wang, AP Hinck, SN Loh, DM LeMaster, JL Markley
Biochemistry 31 (3), 921-936, 1992
611992
O sistema não pode executar a operação agora. Tente novamente mais tarde.
Artigos 1–20