| Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) γ activators and pan-PPAR partial agonists MV Liberato, AS Nascimento, SD Ayers, JZ Lin, A Cvoro, RL Silveira, ... PloS one 7 (5), e36297, 2012 | 216 | 2012 |
| Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function AS Nascimento, SMG Dias, FM Nunes, R Aparício, ALB Ambrosio, ... Journal of molecular biology 360 (3), 586-598, 2006 | 131 | 2006 |
| Structural diversity of carbohydrate esterases AM Nakamura, AS Nascimento, I Polikarpov Biotechnology Research and Innovation 1 (1), 35-51, 2017 | 125 | 2017 |
| Gaining ligand selectivity in thyroid hormone receptors via entropy L Martínez, AS Nascimento, FM Nunes, K Phillips, R Aparicio, SMG Dias, ... Proceedings of the National Academy of Sciences 106 (49), 20717-20722, 2009 | 99 | 2009 |
| The MX2 macromolecular crystallography beamline: a wiggler X-ray source at the LNLS BG Guimarães, L Sanfelici, RT Neuenschwander, F Rodrigues, ... Journal of synchrotron radiation 16 (1), 69-75, 2009 | 89 | 2009 |
| Interleukin-22 forms dimers that are recognized by two interleukin-22R1 receptor chains M de Oliveira Neto, JR Ferreira, D Colau, H Fischer, AS Nascimento, ... Biophysical journal 94 (5), 1754-1765, 2008 | 78 | 2008 |
| Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia) L Watanabe, PR de Moura, L Bleicher, AS Nascimento, LS Zamorano, ... Journal of Structural Biology 169 (2), 226-242, 2010 | 52 | 2010 |
| Identification of a new hormone-binding site on the surface of thyroid hormone receptor PCT Souza, AC Puhl, L Martínez, R Aparício, AS Nascimento, ... Molecular endocrinology 28 (4), 534-545, 2014 | 45 | 2014 |
| Structural and biochemical characterization of a GH3 β-glucosidase from the probiotic bacteria Bifidobacterium adolescentis RN Florindo, VP Souza, LR Manzine, CM Camilo, SR Marana, ... Biochimie 148, 107-115, 2018 | 42 | 2018 |
| Structural insights into β-glucosidase transglycosylation based on biochemical, structural and computational analysis of two GH1 enzymes from Trichoderma harzianum RN Florindo, VP Souza, HS Mutti, C Camilo, LR Manzine, SR Marana, ... New biotechnology 40, 218-227, 2018 | 41 | 2018 |
| Catalytic mechanism of inulinase from Arthrobacter sp. S37 KY Kim, AS Nascimento, AM Golubev, I Polikarpov, CS Kim, SI Kang, ... Biochemical and Biophysical Research Communications 371 (4), 600-605, 2008 | 37 | 2008 |
| An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist position PCT Souza, LC Textor, DC Melo, AS Nascimento, MS Skaf, I Polikarpov Scientific reports 7 (1), 3509, 2017 | 35 | 2017 |
| Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular … L Bleicher, ET Prates, TCF Gomes, RL Silveira, AS Nascimento, AL Rojas, ... The Journal of Physical Chemistry B 115 (24), 7940-7949, 2011 | 35 | 2011 |
| Structure-based virtual screening and discovery of new PPARδ/γ dual agonist and PPARδ and γ agonists VG Maltarollo, M Togashi, AS Nascimento, KM Honorio PloS one 10 (3), e0118790, 2015 | 32 | 2015 |
| Structure-based identification of novel PPAR gamma ligands FMC da Silva, JC dos Santos, JLO Campos, AC Mafud, I Polikarpov, ... Bioorganic & medicinal chemistry letters 23 (21), 5795-5802, 2013 | 32 | 2013 |
| Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+ AS Nascimento, DL Catalano-Dupuy, A Bernardes, MO Neto, ... BMC structural biology 7, 1-12, 2007 | 30 | 2007 |
| Crystal structure of β1→6‐galactosidase from Bifidobacterium bifidum S17: trimeric architecture, molecular determinants of the enzymatic activity and its inhibition … AS Godoy, CM Camilo, MA Kadowaki, HS Muniz, M Espirito Santo, ... The FEBS Journal 283 (22), 4097-4112, 2016 | 28 | 2016 |
| MolShaCS: a free and open source tool for ligand similarity identification based on Gaussian descriptors LACV de Lima, AS Nascimento European journal of medicinal chemistry 59, 296-303, 2013 | 28 | 2013 |
| Insights into the structure and function of fungal β‐mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzyme AS Nascimento, JRC Muniz, R Aparício, AM Golubev, I Polikarpov The FEBS journal 281 (18), 4165-4178, 2014 | 25 | 2014 |
| Essential metabolic routes as a way to ESKAPE from antibiotic resistance ALC Barra, LOC Dantas, LG Morão, RF Gutierrez, I Polikarpov, C Wrenger, ... Frontiers in Public Health 8, 507951, 2020 | 22 | 2020 |
