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Andrew H Laszlo
Andrew H Laszlo
E-mail confirmado em uw.edu
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Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase
EA Manrao, IM Derrington, AH Laszlo, KW Langford, MK Hopper, ...
Nature biotechnology 30 (4), 349-353, 2012
10472012
Decoding long nanopore sequencing reads of natural DNA
AH Laszlo, IM Derrington, BC Ross, H Brinkerhoff, A Adey, IC Nova, ...
Nature biotechnology 32 (8), 829-833, 2014
4922014
Detection and mapping of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore MspA
AH Laszlo, IM Derrington, H Brinkerhoff, KW Langford, IC Nova, ...
Proceedings of the National Academy of Sciences 110 (47), 18904-18909, 2013
3452013
Subangstrom single-molecule measurements of motor proteins using a nanopore
IM Derrington, JM Craig, E Stava, AH Laszlo, BC Ross, H Brinkerhoff, ...
Nature biotechnology 33 (10), 1073-1075, 2015
1322015
Increasing the accuracy of nanopore DNA sequencing using a time-varying cross membrane voltage
MT Noakes, H Brinkerhoff, AH Laszlo, IM Derrington, KW Langford, ...
Nature biotechnology 37 (6), 651-656, 2019
1052019
MspA nanopore as a single-molecule tool: From sequencing to SPRNT
AH Laszlo, IM Derrington, JH Gundlach
Methods 105, 75-89, 2016
872016
Revealing dynamics of helicase translocation on single-stranded DNA using high-resolution nanopore tweezers
JM Craig, AH Laszlo, H Brinkerhoff, IM Derrington, MT Noakes, IC Nova, ...
Proceedings of the National Academy of Sciences 114 (45), 11932-11937, 2017
662017
Determining the effects of DNA sequence on Hel308 helicase translocation along single-stranded DNA using nanopore tweezers
JM Craig, AH Laszlo, IC Nova, H Brinkerhoff, MT Noakes, KS Baker, ...
Nucleic acids research 47 (5), 2506-2513, 2019
382019
Direct detection of unnatural DNA nucleotides dNaM and d5SICS using the MspA nanopore
JM Craig, AH Laszlo, IM Derrington, BC Ross, H Brinkerhoff, IC Nova, ...
PLoS One 10 (11), e0143253, 2015
372015
Investigating asymmetric salt profiles for nanopore DNA sequencing with biological porin MspA
IC Nova, IM Derrington, JM Craig, MT Noakes, BI Tickman, K Doering, ...
PLoS One 12 (7), e0181599, 2017
292017
Subangstrom measurements of enzyme function using a biological nanopore, SPRNT
AH Laszlo, IM Derrrington, JH Gundlach
Methods in enzymology 582, 387-414, 2017
192017
Modelling single-molecule kinetics of helicase translocation using high-resolution nanopore tweezers (SPRNT)
JM Craig, AH Laszlo, IC Nova, JH Gundlach
Essays in biochemistry 65 (1), 109-127, 2021
62021
Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution
AH Laszlo, JM Craig, M Gavrilov, R Tippana, IC Nova, JR Huang, HC Kim, ...
Proceedings of the National Academy of Sciences 119 (36), e2202489119, 2022
52022
Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
SK Marx, KJ Mickolajczyk, JM Craig, CA Thomas, AM Pfeffer, SJ Abell, ...
Nucleic acids research 51 (17), 9266-9278, 2023
3*2023
Assessing readability of an 8-letter expanded deoxyribonucleic acid alphabet with nanopores
CA Thomas, JM Craig, S Hoshika, H Brinkerhoff, JR Huang, SJ Abell, ...
Journal of the American Chemical Society 145 (15), 8560-8568, 2023
32023
Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
JM Craig, M Mills, HC Kim, JR Huang, SJ Abell, JW Mount, JH Gundlach, ...
Nucleic Acids Research 50 (18), 10601-10613, 2022
32022
Enzymatic synthesis and nanopore sequencing of 12-letter supernumerary DNA
H Kawabe, CA Thomas, S Hoshika, MJ Kim, MS Kim, L Miessner, ...
Nature Communications 14 (1), 6820, 2023
12023
MspA porin as a local nanopore probe for membrane-bound proteins
DP Hoogerheide, PA Gurnev, J Gundlach, A Laszlo, TK Rostovtseva, ...
BioRXiv, 2021.10. 15.464579, 2021
12021
Nanopore-based analysis of protein characteristics
J Gundlach, IM Derrington, A Laszlo, J Craig, H Brinkerhoff
US Patent 10,948,454, 2021
12021
Compositions and methods for improving nanopore sequencing
JH Gundlach, A Laszlo
US Patent 10,858,700, 2020
12020
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