| Smad7 antagonizes transforming growth factor β signaling in the nucleus by interfering with functional Smad-DNA complex formation S Zhang, T Fei, L Zhang, R Zhang, F Chen, Y Ning, Y Han, XH Feng, ... Molecular and cellular biology 27 (12), 4488-4499, 2007 | 346 | 2007 |
| ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth S Zhang, L Chen, B Cui, HY Chuang, J Yu, J Wang-Rodriguez, L Tang, ... PloS one 7 (3), e31127, 2012 | 289 | 2012 |
| MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia B Cui, L Chen, S Zhang, M Mraz, JF Fecteau, J Yu, EM Ghia, L Zhang, ... Blood, The Journal of the American Society of Hematology 124 (4), 546-554, 2014 | 242 | 2014 |
| The onco-embryonic antigen ROR1 is expressed by a variety of human cancers S Zhang, L Chen, J Wang-Rodriguez, L Zhang, B Cui, W Frankel, R Wu, ... The American journal of pathology 181 (6), 1903-1910, 2012 | 229 | 2012 |
| Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation J Yu, L Chen, B Cui, GF Widhopf, Z Shen, R Wu, L Zhang, S Zhang, ... The Journal of clinical investigation 126 (2), 585-598, 2016 | 208 | 2016 |
| Axin is a scaffold protein in TGF‐β signaling that promotes degradation of Smad7 by Arkadia W Liu, H Rui, J Wang, S Lin, Y He, M Chen, Q Li, Z Ye, S Zhang, SC Chan, ... The EMBO journal 25 (8), 1646-1658, 2006 | 207 | 2006 |
| Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy S Zhang, B Cui, H Lai, G Liu, EM Ghia, GF Widhopf, Z Zhang, CCN Wu, ... Proceedings of the National Academy of Sciences 111 (48), 17266-17271, 2014 | 194 | 2014 |
| The pathogenesis of chronic lymphocytic leukemia S Zhang, TJ Kipps Annual Review of Pathology: Mechanisms of Disease 9, 103-118, 2014 | 194 | 2014 |
| Targeting ROR1 inhibits epithelial–mesenchymal transition and metastasis B Cui, S Zhang, L Chen, J Yu, GF Widhopf, JF Fecteau, LZ Rassenti, ... Cancer research 73 (12), 3649-3660, 2013 | 187 | 2013 |
| Targeting chronic lymphocytic leukemia cells with a humanized monoclonal antibody specific for CD44 S Zhang, CCN Wu, JF Fecteau, B Cui, L Chen, L Zhang, R Wu, L Rassenti, ... Proceedings of the National Academy of Sciences 110 (15), 6127-6132, 2013 | 125 | 2013 |
| Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody S Zhang, H Zhang, EM Ghia, J Huang, L Wu, J Zhang, S Lam, Y Lei, J He, ... Proceedings of the National Academy of Sciences 116 (4), 1370-1377, 2019 | 111 | 2019 |
| Wnt5a signaling in normal and cancer stem cells Y Zhou, TJ Kipps, S Zhang Stem cells international 2017, 2017 | 76 | 2017 |
| Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia Y Chen, L Chen, J Yu, EM Ghia, MY Choi, L Zhang, S Zhang, ... Blood, The Journal of the American Society of Hematology 134 (13), 1084-1094, 2019 | 50 | 2019 |
| Study of interaction between Smad7 and DNA by single-molecule force spectroscopy X Shi, F Chen, J Yu, Y Xu, S Zhang, YG Chen, X Fang Biochemical and biophysical research communications 377 (4), 1284-1287, 2008 | 36 | 2008 |
| Aurora B induces epithelial–mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis J Zhang, X Lin, L Wu, JJ Huang, WQ Jiang, TJ Kipps, S Zhang Oncogene 39 (12), 2550-2567, 2020 | 28 | 2020 |
| Yin Yang 1 (YY1) synergizes with Smad7 to inhibit TGF-β signaling in the nucleus XH Yan, J Pan, WW Xiong, MZ Cheng, YY Sun, SP Zhang, YG Chen Science China Life Sciences 57, 128-136, 2014 | 27 | 2014 |
| Wnt5a induces ROR1 to recruit cortactin to promote breast-cancer migration and metastasis MK Hasan, GF Widhopf, S Zhang, SM Lam, Z Shen, SP Briggs, BA Parker, ... NPJ Breast Cancer 5 (1), 35, 2019 | 24 | 2019 |
| Impact of oxygen concentration on growth of mesenchymal stromal cells from the marrow of patients with chronic lymphocytic leukemia JF Fecteau, D Messmer, S Zhang, B Cui, L Chen, TJ Kipps Blood, The Journal of the American Society of Hematology 121 (6), 971-974, 2013 | 24 | 2013 |
| Methods and compounds for lymphoma cell detection and isolation TJ Kipps, T Fukuda, T Endo, S Zhang, L Chen, HE Broome US Patent 8,212,009, 2012 | 24 | 2012 |
| Cirmtuzumab vedotin (UC-961ADC3), an anti-ROR1-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for ROR1-positive leukemia and solid tumors B Cui, GF Widhopf II, CE Prussak, CCN Wu, A Sadarangani, S Zhang, ... Blood 122 (21), 1637, 2013 | 23 | 2013 |
