Massimo Libra
Massimo Libra
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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
JA McCubrey, LS Steelman, WH Chappell, SL Abrams, EWT Wong, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (8), 1263-1284, 2007
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
JA McCubrey, LS Steelman, SL Abrams, JT Lee, F Chang, FE Bertrand, ...
Advances in enzyme regulation 46 (1), 249-279, 2006
Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging
LS Steelman, WH Chappell, SL Abrams, CR Kempf, J Long, P Laidler, ...
Aging (Albany NY) 3 (3), 192, 2011
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health
WH Chappell, LS Steelman, JM Long, RC Kempf, SL Abrams, RA Franklin, ...
Oncotarget 2 (3), 135, 2011
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia
LS Steelman, SL Abrams, J Whelan, FE Bertrand, DE Ludwig, J Bäsecke, ...
Leukemia 22 (4), 686-707, 2008
GSK-3 as potential target for therapeutic intervention in cancer
JA McCubrey, LS Steelman, FE Bertrand, NM Davis, M Sokolosky, ...
Oncotarget 5 (10), 2881, 2014
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance
JA McCubrey, LS Steelman, WH Chappell, SL Abrams, RA Franklin, ...
Oncotarget 3 (10), 1068, 2012
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response
JA McCubrey, LS Steelman, WH Chappell, SL Abrams, G Montalto, ...
Oncotarget 3 (9), 954, 2012
Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use
GM Nitulescu, D Margina, P Juzenas, Q Peng, OT Olaru, E Saloustros, ...
International journal of oncology 48 (3), 869-885, 2016
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy
JA McCubrey, LS Steelman, SL Abrams, FE Bertrand, DE Ludwig, ...
Leukemia 22 (4), 708-722, 2008
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy
LS Steelman, RA Franklin, SL Abrams, W Chappell, CR Kempf, J Bäsecke, ...
Leukemia 25 (7), 1080-1094, 2011
Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention
NM Davis, M Sokolosky, K Stadelman, SL Abrams, M Libra, S Candido, ...
Oncotarget 5 (13), 4603, 2014
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy
N Misaghian, G Ligresti, LS Steelman, FE Bertrand, J Bäsecke, M Libra, ...
Leukemia 23 (1), 25-42, 2009
Evolution of cancer pharmacological treatments at the turn of the third millennium
L Falzone, S Salomone, M Libra
Frontiers in pharmacology 9, 1300, 2018
Cutaneous melanoma: From pathogenesis to therapy
GC Leonardi, L Falzone, R Salemi, A Zanghì, DA Spandidos, ...
International journal of oncology 52 (4), 1071-1080, 2018
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
JA McCubrey, LS Steelman, FE Bertrand, NM Davis, SL Abrams, ...
Leukemia 28 (1), 15-33, 2014
Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway
AM Martelli, C Evangelisti, W Chappell, SL Abrams, J Bäsecke, F Stivala, ...
Leukemia 25 (7), 1064-1079, 2011
The tumor microenvironment in hepatocellular carcinoma
GC Leonardi, S Candido, M Cervello, D Nicolosi, F Raiti, S Travali, ...
International journal of oncology 40 (6), 1733-1747, 2012
PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches
G Ligresti, L Militello, LS Steelman, A Cavallaro, F Basile, F Nicoletti, ...
Cell cycle 8 (9), 1352-1358, 2009
Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways
JA McCubrey, LS Steelman, CR Kempf, WH Chappell, SL Abrams, ...
Journal of cellular physiology 226 (11), 2762-2781, 2011
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