CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence CL Stallings, NC Stephanou, L Chu, A Hochschild, BE Nickels, ... Cell 138 (1), 146-159, 2009 | 267 | 2009 |
Structural basis for bacterial transcription-coupled DNA repair AM Deaconescu, AL Chambers, AJ Smith, BE Nickels, A Hochschild, ... Cell 124 (3), 507-520, 2006 | 243 | 2006 |
5′ end nicotinamide adenine dinucleotide cap in human cells promotes RNA decay through DXO-mediated deNADding X Jiao, SK Doamekpor, JG Bird, BE Nickels, L Tong, RP Hart, M Kiledjian Cell 168 (6), 1015-1027. e10, 2017 | 233 | 2017 |
The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoA JG Bird, Y Zhang, Y Tian, N Panova, I Barvík, L Greene, M Liu, B Buckley, ... Nature 535 (7612), 444-447, 2016 | 214 | 2016 |
A role for interaction of the RNA polymerase flap domain with the σ subunit in promoter recognition K Kuznedelov, L Minakhin, A Niedziela-Majka, SL Dove, D Rogulja, ... Science 295 (5556), 855-857, 2002 | 205 | 2002 |
Interactions between RNA polymerase and the “core recognition element” counteract pausing IO Vvedenskaya, H Vahedian-Movahed, JG Bird, JG Knoblauch, ... Science 344 (6189), 1285-1289, 2014 | 189 | 2014 |
Direct detection of abortive RNA transcripts in vivo SR Goldman, RH Ebright, BE Nickels Science 324 (5929), 927-928, 2009 | 165 | 2009 |
NanoRNAs prime transcription initiation in vivo SR Goldman, JS Sharp, IO Vvedenskaya, J Livny, SL Dove, BE Nickels Molecular cell 42 (6), 817-825, 2011 | 134 | 2011 |
An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3 JM Schifano, IO Vvedenskaya, JG Knoblauch, M Ouyang, BE Nickels, ... Nature communications 5 (1), 3538, 2014 | 117 | 2014 |
Cofactor requirements and reconstitution of microcin B17 synthetase: a multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17 JC Milne, RS Roy, AC Eliot, NL Kelleher, A Wokhlu, B Nickels, CT Walsh Biochemistry 38 (15), 4768-4781, 1999 | 111 | 1999 |
Structure of a ternary transcription activation complex D Jain, BE Nickels, L Sun, A Hochschild, SA Darst Molecular cell 13 (1), 45-53, 2004 | 110 | 2004 |
tRNA is a new target for cleavage by a MazF toxin JM Schifano, JW Cruz, IO Vvedenskaya, R Edifor, M Ouyang, RN Husson, ... Nucleic acids research 44 (3), 1256-1270, 2016 | 107 | 2016 |
The interaction between σ70 and the β-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation BE Nickels, SJ Garrity, V Mekler, L Minakhin, K Severinov, RH Ebright, ... Proceedings of the National Academy of Sciences 102 (12), 4488-4493, 2005 | 104 | 2005 |
Protein–protein and protein–DNA interactions of σ70 region 4 involved in transcription activation by λcI BE Nickels, SL Dove, KS Murakami, SA Darst, A Hochschild Journal of molecular biology 324 (1), 17-34, 2002 | 104 | 2002 |
The σ70 subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter BE Nickels, J Mukhopadhyay, SJ Garrity, RH Ebright, A Hochschild Nature structural & molecular biology 11 (6), 544-550, 2004 | 103 | 2004 |
Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase JW Cruz, JD Sharp, ED Hoffer, T Maehigashi, IO Vvedenskaya, ... Nature communications 6 (1), 7480, 2015 | 98 | 2015 |
Regulation of RNA polymerase through the secondary channel BE Nickels, A Hochschild Cell 118 (3), 281-284, 2004 | 89 | 2004 |
Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction LF Westblade, EA Campbell, C Pukhrambam, JC Padovan, BE Nickels, ... Nucleic acids research 38 (22), 8357-8369, 2010 | 83 | 2010 |
Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase JG Bird, U Basu, D Kuster, A Ramachandran, E Grudzien-Nogalska, ... Elife 7, e42179, 2018 | 80 | 2018 |
CapZyme-seq comprehensively defines promoter-sequence determinants for RNA 5′ capping with NAD+ IO Vvedenskaya, JG Bird, Y Zhang, Y Zhang, X Jiao, I Barvík, L Krásný, ... Molecular Cell 70 (3), 553-564. e9, 2018 | 78 | 2018 |