Bryce E Nickels
Bryce E Nickels
Professor of Genetics, Rutgers University
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CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence
CL Stallings, NC Stephanou, L Chu, A Hochschild, BE Nickels, ...
Cell 138 (1), 146-159, 2009
Structural basis for bacterial transcription-coupled DNA repair
AM Deaconescu, AL Chambers, AJ Smith, BE Nickels, A Hochschild, ...
Cell 124 (3), 507-520, 2006
5′ end nicotinamide adenine dinucleotide cap in human cells promotes RNA decay through DXO-mediated deNADding
X Jiao, SK Doamekpor, JG Bird, BE Nickels, L Tong, RP Hart, M Kiledjian
Cell 168 (6), 1015-1027. e10, 2017
The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoA
JG Bird, Y Zhang, Y Tian, N Panova, I Barvík, L Greene, M Liu, B Buckley, ...
Nature 535 (7612), 444-447, 2016
A role for interaction of the RNA polymerase flap domain with the σ subunit in promoter recognition
K Kuznedelov, L Minakhin, A Niedziela-Majka, SL Dove, D Rogulja, ...
Science 295 (5556), 855-857, 2002
Interactions between RNA polymerase and the “core recognition element” counteract pausing
IO Vvedenskaya, H Vahedian-Movahed, JG Bird, JG Knoblauch, ...
Science 344 (6189), 1285-1289, 2014
Direct detection of abortive RNA transcripts in vivo
SR Goldman, RH Ebright, BE Nickels
Science 324 (5929), 927-928, 2009
NanoRNAs prime transcription initiation in vivo
SR Goldman, JS Sharp, IO Vvedenskaya, J Livny, SL Dove, BE Nickels
Molecular cell 42 (6), 817-825, 2011
An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3
JM Schifano, IO Vvedenskaya, JG Knoblauch, M Ouyang, BE Nickels, ...
Nature communications 5 (1), 3538, 2014
Cofactor requirements and reconstitution of microcin B17 synthetase: a multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17
JC Milne, RS Roy, AC Eliot, NL Kelleher, A Wokhlu, B Nickels, CT Walsh
Biochemistry 38 (15), 4768-4781, 1999
Structure of a ternary transcription activation complex
D Jain, BE Nickels, L Sun, A Hochschild, SA Darst
Molecular cell 13 (1), 45-53, 2004
tRNA is a new target for cleavage by a MazF toxin
JM Schifano, JW Cruz, IO Vvedenskaya, R Edifor, M Ouyang, RN Husson, ...
Nucleic acids research 44 (3), 1256-1270, 2016
The interaction between σ70 and the β-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation
BE Nickels, SJ Garrity, V Mekler, L Minakhin, K Severinov, RH Ebright, ...
Proceedings of the National Academy of Sciences 102 (12), 4488-4493, 2005
Protein–protein and protein–DNA interactions of σ70 region 4 involved in transcription activation by λcI
BE Nickels, SL Dove, KS Murakami, SA Darst, A Hochschild
Journal of molecular biology 324 (1), 17-34, 2002
The σ70 subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter
BE Nickels, J Mukhopadhyay, SJ Garrity, RH Ebright, A Hochschild
Nature structural & molecular biology 11 (6), 544-550, 2004
Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase
JW Cruz, JD Sharp, ED Hoffer, T Maehigashi, IO Vvedenskaya, ...
Nature communications 6 (1), 7480, 2015
Regulation of RNA polymerase through the secondary channel
BE Nickels, A Hochschild
Cell 118 (3), 281-284, 2004
Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction
LF Westblade, EA Campbell, C Pukhrambam, JC Padovan, BE Nickels, ...
Nucleic acids research 38 (22), 8357-8369, 2010
The σ70 subunit of RNA polymerase is contacted by the λQ antiterminator during early elongation
BE Nickels, CW Roberts, H Sun, JW Roberts, A Hochschild
Molecular cell 10 (3), 611-622, 2002
Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase
JG Bird, U Basu, D Kuster, A Ramachandran, E Grudzien-Nogalska, ...
Elife 7, e42179, 2018
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