Seguir
Vivek Bhaskaran
Vivek Bhaskaran
Harvard Medical School/Repare Therapeutics
E-mail confirmado em sonatatx.com
Título
Citado por
Citado por
Ano
Arming an oncolytic herpes simplex virus type 1 with a single-chain fragment variable antibody against PD-1 for experimental glioblastoma therapy
C Passaro, Q Alayo, I DeLaura, J McNulty, K Grauwet, H Ito, V Bhaskaran, ...
Clinical Cancer Research 25 (1), 290-299, 2019
1072019
The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma
V Bhaskaran, MO Nowicki, M Idriss, MA Jimenez, G Lugli, JL Hayes, ...
Nature communications 10 (1), 442, 2019
1032019
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
D Gallo, JTF Young, J Fourtounis, G Martino, A Álvarez-Quilón, C Bernier, ...
Nature 604 (7907), 749-756, 2022
892022
The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer
S Adam, SE Rossi, N Moatti, M De Marco Zompit, Y Xue, TF Ng, ...
Nature cancer 2 (12), 1357-1371, 2021
692021
Tumor-derived fibulin-3 activates pro-invasive NF-κB signaling in glioblastoma cells and their microenvironment
MS Nandhu, A Kwiatkowska, V Bhaskaran, J Hayes, B Hu, MS Viapiano
Oncogene 36 (34), 4875-4886, 2017
352017
Development of a function-blocking antibody against fibulin-3 as a targeted reagent for glioblastoma
MS Nandhu, P Behera, V Bhaskaran, SL Longo, LM Barrera-Arenas, ...
Clinical Cancer Research 24 (4), 821-833, 2018
282018
Discovery of an orally bioavailable and selective PKMYT1 inhibitor, RP-6306
J Szychowski, R Papp, E Dietrich, B Liu, F Vallée, ME Leclaire, ...
Journal of medicinal chemistry 65 (15), 10251-10284, 2022
132022
Engineering, delivery, and biological validation of artificial microRNA clusters for gene therapy applications
V Bhaskaran, Y Yao, F Bei, P Peruzzi
Nature protocols 14 (12), 3538-3553, 2019
132019
Structure of an amidohydrolase, SACOL0085, from methicillin-resistant Staphylococcus aureus COL
TS Girish, B Vivek, M Colaco, S Misquith, B Gopal
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
102013
Correction: arming an oncolytic herpes simplex virus type 1 with a single-chain fragment variable antibody against PD-1 for experimental glioblastoma therapy
C Passaro, Q Alayo, I DeLaura, J McNulty, K Grauwet, H Ito, V Bhaskaran, ...
Clinical Cancer Research 26 (3), 758-758, 2020
82020
CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers. bioRxiv Published online February 8, 2021
S Adam
22021
Characterization of functionally associated miRNAs in glioblastoma and their engineering into artificial clusters for gene therapy
V Bhaskaran, P Peruzzi
JoVE (Journal of Visualized Experiments), e60215, 2019
22019
MicroRNAs in brain cancer: look at the forest, not at the tree
P Peruzzi, V Bhaskaran
Journal of Experimental Neuroscience 13, 1179069519839693, 2019
12019
Abstract C163: KRAS alterations combined with TP53 mutations as novel synthetic lethal genomic lesions for PKMYT1 inhibition
ML Hyer, J Fourtounis, D Gallo, V Bhaskaran, R Stocco, R Kryczka, ...
NaN, C163-C163, 2023
2023
The PKMYT1 inhibitor RP-6306 has synergistic efficacy with carboplatin in CCNE1 amplified tumor models
J Fourtounis, D Gallo, A Roulston, R Stocco, G Martino, S Fournier, ...
European Journal of Cancer 174, S61, 2022
2022
Regulation of the protease ADAM17 by extracellular signals drives pro-tumoral programs in glioblastoma cells and their microenvironment.
NM Sobhana, V Bhaskaran, B Hu, M Viapiano
SNO 2017 Annual Meeting, 2017
2017
Regulation Of The Protease Adam17 By Extracellular Signals Drives Pro-tumoral Programs In Glioblastoma Cells And Their Microenvironment.
MS Nandhu, V Bhaskaran, B Hu, M Viapiano
Neuro-oncology 19 (suppl_6), vi253, 2017
2017
An Engineered microrna Cluster For Broad Targeting Of Epigenetic Complexes In Gbm
V Bhaskaran, M Idriss, SE Lawler, EA Chiocca, PP Peruzzi
Neuro-oncology 19 (suppl_6), vi88, 2017
2017
GENT-24. LONG NON-CODING RNA CRNDE AS A POTENTIAL EGFR-REGULATED ONCOGENE IN GLIOMA
P Peruzzi, V Bhaskaran, M Idriss, J Godlewski, EA Chiocca, SE Lawler, ...
NEURO-ONCOLOGY, 2016
2016
Functionally Clustered microRNAs for GBM Reprogramming and Therapy
P Peruzzi, V Bhaskaran
Neuro-Oncology 18 (suppl 6), vi79-vi79, 2016
2016
O sistema não pode executar a operação agora. Tente novamente mais tarde.
Artigos 1–20