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Ujjal Singha
Ujjal Singha
Vanderbilt University MedicaLCenter
E-mail confirmado em vumc.org
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Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)–dependent migration and homing in multiple myeloma
Y Alsayed, H Ngo, J Runnels, X Leleu, UK Singha, CM Pitsillides, ...
Blood 109 (7), 2708-2717, 2007
5762007
Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3‐E1 cells and primary mouse bone marrow stromal cells
UK Singha, Y Jiang, S Yu, M Luo, Y Lu, J Zhang, G Xiao
Journal of cellular biochemistry 103 (2), 434-446, 2008
2042008
Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma
LK Francis, Y Alsayed, X Leleu, X Jia, UK Singha, J Anderson, M Timm, ...
Clinical cancer research 12 (22), 6826-6835, 2006
1002006
Characterization of the mitochondrial inner membrane protein translocator Tim17 from Trypanosoma brucei
UK Singha, E Peprah, S Williams, R Walker, L Saha, M Chaudhuri
Molecular and biochemical parasitology 159 (1), 30-43, 2008
632008
Protein translocase of mitochondrial inner membrane in Trypanosoma brucei
UK Singha, VN Hamilton, MR Duncan, E Weems, MK Tripathi, ...
Journal of Biological Chemistry 287 (18), 14480-14493, 2012
522012
Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms
CR Nes, UK Singha, J Liu, K Ganapathy, F Villalta, MR Waterman, ...
Biochemical Journal 443 (1), 267-277, 2012
492012
Downregulation of Mitochondrial Porin Inhibits Cell Growth and Alters Respiratory Phenotype in Trypanosoma brucei
UK Singha, S Sharma, M Chaudhuri
Eukaryotic cell 8 (9), 1418-1428, 2009
342009
Role of Tob55 on mitochondrial protein biogenesis in Trypanosoma brucei
S Sharma, UK Singha, M Chaudhuri
Molecular and biochemical parasitology 174 (2), 89-100, 2010
332010
Protein phosphatase 5 is required for Hsp90 function during proteotoxic stresses in Trypanosoma brucei
C Jones, S Anderson, UK Singha, M Chaudhuri
Parasitology research 102, 835-844, 2008
302008
Trypanosoma brucei: differential requirement of membrane potential for import of proteins into mitochondria in two developmental stages
S Williams, L Saha, UK Singha, M Chaudhuri
Experimental parasitology 118 (3), 420-433, 2008
292008
Tim62, a novel mitochondrial protein in Trypanosoma brucei, is essential for assembly and stability of the TbTim17 protein complex
UK Singha, VN Hamilton, M Chaudhuri
Journal of Biological Chemistry 290 (38), 23226-23239, 2015
282015
Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth [S]
BA Haubrich, UK Singha, MB Miller, CR Nes, H Anyatonwu, L Lecordier, ...
Journal of lipid research 56 (2), 331-341, 2015
252015
Sterol methyltransferase a target for anti-amoeba therapy: towards transition state analog and suicide substrate drug design
ME Kidane, BH Vanderloop, W Zhou, CD Thomas, E Ramos, U Singha, ...
Journal of lipid research 58 (12), 2310-2323, 2017
242017
Trypanosome alternative oxidase possesses both an N-terminal and internal mitochondrial targeting signal
VN Hamilton, UK Singha, JT Smith, E Weems, M Chaudhuri
Eukaryotic cell 13 (4), 539-547, 2014
242014
Fluorinated sterols are suicide inhibitors of ergosterol biosynthesis and growth in Trypanosoma brucei
DJ Leaver, P Patkar, UK Singha, MB Miller, BA Haubrich, M Chaudhuri, ...
Chemistry & biology 22 (10), 1374-1383, 2015
212015
Tim17 updates: A comprehensive review of an ancient mitochondrial protein translocator
M Chaudhuri, C Darden, F Soto Gonzalez, UK Singha, L Quinones, ...
Biomolecules 10 (12), 1643, 2020
192020
Divergent Small Tim Homologues Are Associated with TbTim17 and Critical for the Biogenesis of TbTim17 Protein Complexes in Trypanosoma brucei
JT Smith Jr, UK Singha, S Misra, M Chaudhuri
Msphere 3 (3), 10.1128/msphere. 00204-18, 2018
192018
Functional complementation analyses reveal that the single PRAT family protein of Trypanosoma brucei is a divergent homolog of Tim17 in Saccharomyces cerevisiae
E Weems, UK Singha, VN Hamilton, JT Smith, K Waegemann, ...
Eukaryotic Cell 14 (3), 286-296, 2015
162015
Down regulation of Tim50 in Trypanosoma brucei increases tolerance to oxidative stress
M Fullerton, UK Singha, M Duncan, M Chaudhuri
Molecular and biochemical parasitology 199 (1-2), 9-18, 2015
142015
24-Methylenecyclopropane steroidal inhibitors: A Trojan horse in ergosterol biosynthesis that prevents growth of Trypanosoma brucei
MB Miller, P Patkar, UK Singha, M Chaudhuri, WD Nes
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017
122017
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