| Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus CT De Souza, EP Araujo, S Bordin, R Ashimine, RL Zollner, AC Boschero, ... Endocrinology 146 (10), 4192-4199, 2005 | 1314 | 2005 |
| Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ... Journal of Neuroscience 29 (2), 359-370, 2009 | 1205 | 2009 |
| Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance DML Tsukumo, MA Carvalho-Filho, JBC Carvalheira, PO Prada, ... Diabetes 56 (8), 1986-1998, 2007 | 1058 | 2007 |
| Elevated glucose levels favor SARS-CoV-2 infection and monocyte response through a HIF-1α/glycolysis-dependent axis AC Codo, GG Davanzo, L de Brito Monteiro, GF de Souza, SP Muraro, ... Cell metabolism 32 (3), 437-446. e5, 2020 | 844 | 2020 |
| Endoplasmic reticulum stress, obesity and diabetes M Cnop, F Foufelle, LA Velloso Trends in molecular medicine 18 (1), 59-68, 2012 | 772 | 2012 |
| High-fat diet induces apoptosis of hypothalamic neurons JC Moraes, A Coope, J Morari, DE Cintra, EA Roman, JR Pauli, ... PloS one 4 (4), e5045, 2009 | 498 | 2009 |
| Cross-talk between the insulin and angiotensin signaling systems. LA Velloso, F Folli, XJ Sun, MF White, MJ Saad, CR Kahn Proceedings of the National Academy of Sciences 93 (22), 12490-12495, 1996 | 488 | 1996 |
| IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition ER Ropelle, MB Flores, DE Cintra, GZ Rocha, JR Pauli, J Morari, ... PLoS biology 8 (8), e1000465, 2010 | 460 | 2010 |
| Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity DE Cintra, ER Ropelle, JC Moraes, JR Pauli, J Morari, CT de Souza, ... PloS one 7 (1), e30571, 2012 | 415 | 2012 |
| TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ... Cell metabolism 18 (6), 831-843, 2013 | 392 | 2013 |
| S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance MA Carvalho-Filho, M Ueno, SM Hirabara, AB Seabra, JBC Carvalheira, ... Diabetes 54 (4), 959-967, 2005 | 334 | 2005 |
| TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation LA Velloso, F Folli, MJ Saad Endocrine reviews 36 (3), 245-271, 2015 | 280 | 2015 |
| A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet–induced weight loss ER Ropelle, JR Pauli, MFA Fernandes, SA Rocco, RM Marin, J Morari, ... Diabetes 57 (3), 594-605, 2008 | 249 | 2008 |
| Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver M Milanski, AP Arruda, A Coope, LM Ignacio-Souza, CE Nunez, ... Diabetes 61 (6), 1455-1462, 2012 | 245 | 2012 |
| Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial MHM Lima, AM Caricilli, LL de Abreu, EP Araújo, FF Pelegrinelli, ... PloS one 7 (5), e36974, 2012 | 239 | 2012 |
| Interleukin-10 is a protective factor against diet-induced insulin resistance in liver DE Cintra, JR Pauli, EP Araújo, JC Moraes, CT de Souza, M Milanski, ... Journal of hepatology 48 (4), 628-637, 2008 | 228 | 2008 |
| Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet R Barbuio, M Milanski, MB Bertolo, MJ Saad, LA Velloso Journal of Endocrinology 194 (3), 539-550, 2007 | 226 | 2007 |
| Crosstalk between insulin and angiotensin II signalling systems F Folli, MJA Saad, L Velloso, H Hansen, O Carandente, EP Feener, ... Experimental and clinical endocrinology & diabetes 107 (02), 133-139, 1999 | 226 | 1999 |
| Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver NG Ashino, KN Saito, FD Souza, FS Nakutz, EA Roman, LA Velloso, ... The Journal of nutritional biochemistry 23 (4), 341-348, 2012 | 221 | 2012 |
| Reversal of diet‐induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS‐1 serine phosphorylation ER Ropelle, JR Pauli, PO Prada, CT De Souza, PK Picardi, MC Faria, ... The Journal of physiology 577 (3), 997-1007, 2006 | 220 | 2006 |
