LICIO Augusto Velloso
LICIO Augusto Velloso
Professor of Medicine, University of Campinas
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Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
CT De Souza, EP Araujo, S Bordin, R Ashimine, RL Zollner, AC Boschero, ...
Endocrinology 146 (10), 4192-4199, 2005
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity
M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ...
Journal of Neuroscience 29 (2), 359-370, 2009
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
DML Tsukumo, MA Carvalho-Filho, JBC Carvalheira, PO Prada, ...
Diabetes 56 (8), 1986-1998, 2007
Elevated glucose levels favor SARS-CoV-2 infection and monocyte response through a HIF-1α/glycolysis-dependent axis
AC Codo, GG Davanzo, L de Brito Monteiro, GF de Souza, SP Muraro, ...
Cell metabolism 32 (3), 437-446. e5, 2020
Endoplasmic reticulum stress, obesity and diabetes
M Cnop, F Foufelle, LA Velloso
Trends in molecular medicine 18 (1), 59-68, 2012
High-fat diet induces apoptosis of hypothalamic neurons
JC Moraes, A Coope, J Morari, DE Cintra, EA Roman, JR Pauli, ...
PloS one 4 (4), e5045, 2009
Cross-talk between the insulin and angiotensin signaling systems.
LA Velloso, F Folli, XJ Sun, MF White, MJ Saad, CR Kahn
Proceedings of the National Academy of Sciences 93 (22), 12490-12495, 1996
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition
ER Ropelle, MB Flores, DE Cintra, GZ Rocha, JR Pauli, J Morari, ...
PLoS biology 8 (8), e1000465, 2010
Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity
DE Cintra, ER Ropelle, JC Moraes, JR Pauli, J Morari, CT de Souza, ...
PloS one 7 (1), e30571, 2012
TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys
MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ...
Cell metabolism 18 (6), 831-843, 2013
S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance
MA Carvalho-Filho, M Ueno, SM Hirabara, AB Seabra, JBC Carvalheira, ...
Diabetes 54 (4), 959-967, 2005
TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation
LA Velloso, F Folli, MJ Saad
Endocrine reviews 36 (3), 245-271, 2015
A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet–induced weight loss
ER Ropelle, JR Pauli, MFA Fernandes, SA Rocco, RM Marin, J Morari, ...
Diabetes 57 (3), 594-605, 2008
Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver
M Milanski, AP Arruda, A Coope, LM Ignacio-Souza, CE Nunez, ...
Diabetes 61 (6), 1455-1462, 2012
Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial
MHM Lima, AM Caricilli, LL de Abreu, EP Araújo, FF Pelegrinelli, ...
PloS one 7 (5), e36974, 2012
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
DE Cintra, JR Pauli, EP Araújo, JC Moraes, CT de Souza, M Milanski, ...
Journal of hepatology 48 (4), 628-637, 2008
Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet
R Barbuio, M Milanski, MB Bertolo, MJ Saad, LA Velloso
Journal of Endocrinology 194 (3), 539-550, 2007
Crosstalk between insulin and angiotensin II signalling systems
F Folli, MJA Saad, L Velloso, H Hansen, O Carandente, EP Feener, ...
Experimental and clinical endocrinology & diabetes 107 (02), 133-139, 1999
Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver
NG Ashino, KN Saito, FD Souza, FS Nakutz, EA Roman, LA Velloso, ...
The Journal of nutritional biochemistry 23 (4), 341-348, 2012
Altered hypothalamic function in diet-induced obesity
LA Velloso, MW Schwartz
International journal of obesity 35 (12), 1455-1465, 2011
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