| Digitonin permeabilization does not affect mitochondrial function and allows the determination of the mitochondrial membrane potential of Trypanosoma cruzi in situ AE Vercesi, CF Bernardes, ME Hoffmann, FR Gadelha, R Docampo Journal of Biological Chemistry 266 (22), 14431-14434, 1991 | 215 | 1991 |
| Ca2+-independent permeabilization of the inner mitochondrial membrane by peroxynitrite is mediated by membrane protein thiol cross-linking and lipid peroxidation FR Gadelha, L Thomson, MM Fagian, ADT Costa, R Radi, AE Vercesi Archives of biochemistry and biophysics 345 (2), 243-250, 1997 | 144 | 1997 |
| Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis LM Alcântara, TCS Ferreira, FR Gadelha, DC Miguel International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 430-439, 2018 | 116 | 2018 |
| Trypanosoma cruzi response to the oxidative stress generated by hydrogen peroxide JK Finzi, CWM Chiavegatto, KF Corat, JA Lopez, OG Cabrera, ... Molecular and biochemical parasitology 133 (1), 37-43, 2004 | 107 | 2004 |
| Oxidative Stress and DNA Lesions: The Role of 8-Oxoguanine Lesions in Trypanosoma cruzi Cell Viability PHN Aguiar, C Furtado, BM Repolês, GA Ribeiro, IC Mendes, EF Peloso, ... PLoS neglected tropical diseases 7 (6), e2279, 2013 | 103 | 2013 |
| How Trypanosoma cruzi deals with oxidative stress: Antioxidant defence and DNA repair pathways A Machado-Silva, PG Cerqueira, V Grazielle-Silva, FR Gadelha, ... Mutation Research/Reviews in Mutation Research 767, 8-22, 2016 | 91 | 2016 |
| A calmodulin-activated (Ca2+-Mg2+)-ATPase is involved in Ca2+ transport by plasma membrane vesicles from Trypanosoma cruzi G Benaim, S Losada, FR Gadelha, R Docampo Biochemical Journal 280 (3), 715-720, 1991 | 87 | 1991 |
| A comparative assessment of mitochondrial function in epimastigotes and bloodstream trypomastigotes of Trypanosoma cruzi RLS Gonçalves, RFSM Barreto, CR Polycarpo, FR Gadelha, SL Castro, ... Journal of bioenergetics and biomembranes 43, 651-661, 2011 | 80 | 2011 |
| Mitochondrial calcium overload triggers complement-dependent superoxide-mediated programmed cell death in Trypanosoma cruzi F Irigoin, NM Inada, MP Fernandes, L Piacenza, FR Gadelha, AE Vercesi, ... Biochemical Journal 418 (3), 595-604, 2009 | 80 | 2009 |
| A promising action of riboflavin as a mediator of leukaemia cell death ACS De Souza, L Kodach, FR Gadelha, CL Bos, ADM Cavagis, ... Apoptosis 11, 1761-1771, 2006 | 68 | 2006 |
| Chemical composition of the essential oils of Annona pickelii and Annona salzmannii (Annonaceae), and their antitumour and trypanocidal activities EV Costa, LM Dutra, MJ Salvador, LHG Ribeiro, FR Gadelha, ... Natural Product Research 27 (11), 997-1001, 2013 | 61 | 2013 |
| Cytotoxicity of goniothalamin enantiomers in renal cancer cells: involvement of nitric oxide, apoptosis and autophagy  de Fátima, WF Zambuzzi, LV Modolo, CAB Tarsitano, FR Gadelha, ... Chemico-biological interactions 176 (2-3), 143-150, 2008 | 60 | 2008 |
| Essential Oil from the Leaves of Annona vepretorum: Chemical Composition and Bioactivity EV Costa, LM Dutra, PCL Nogueira, VRS Moraes, MJ Salvador, ... Natural Product Communications 7 (2), 1934578X1200700240, 2012 | 55 | 2012 |
| Isolation, Derivative Synthesis, and Structure–Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis LLL Parra, AF Bertonha, IRM Severo, ACC Aguiar, GE de Souza, G Oliva, ... Journal of natural products 81 (1), 188-202, 2018 | 54 | 2018 |
| Redox metabolism in Trypanosoma cruzi: functional characterization of tryparedoxins revisited DG Arias, VE Marquez, ML Chiribao, FR Gadelha, C Robello, AA Iglesias, ... Free Radical Biology and Medicine 63, 65-77, 2013 | 53 | 2013 |
| Mechanism of Trypanosoma cruzi death induced by Cratylia mollis seed lectin MP Fernandes, NM Inada, MR Chiaratti, FFB Araújo, FV Meirelles, ... Journal of bioenergetics and biomembranes 42, 69-78, 2010 | 53 | 2010 |
| Mitochondrial bioenergetics and redox state are unaltered in Trypanosoma cruzi isolates with compromised mitochondrial complex I subunit genes J César Carranza, AJ Kowaltowski, MAG Mendonça, TC de Oliveira, ... Journal of Bioenergetics and Biomembranes 41, 299-308, 2009 | 53 | 2009 |
| Prevention of Chagas' disease resulting from blood transfusion by treatment of blood: toxicity and mode of action of gentian violet. R Docampo, SN Moreno, FR Gadelha, W De Souza, FS Cruz Biomedical and environmental sciences: BES 1 (4), 406-413, 1988 | 48 | 1988 |
| The Influence of Low Oxygen on Macrophage Response to Leishmania Infection A Degrossoli, WW Arrais‐Silva, MC Colhone, FR Gadelha, PP Joazeiro, ... Scandinavian Journal of Immunology 74 (2), 165-175, 2011 | 47 | 2011 |
| Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response PC Campos, VG Silva, C Furtado, A Machado-Silva, WD DaRocha, ... Molecular and biochemical parasitology 176 (1), 8-16, 2011 | 46 | 2011 |
