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Brad Dykstra
Brad Dykstra
Post-doctoral fellow, Brigham and Womens Hospital / Harvard Medical School
E-mail confirmado em partners.org
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Long-term propagation of distinct hematopoietic differentiation programs in vivo
B Dykstra, D Kent, M Bowie, L McCaffrey, M Hamilton, K Lyons, SJ Lee, ...
Cell stem cell 1 (2), 218-229, 2007
7302007
Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
B Dykstra, S Olthof, J Schreuder, M Ritsema, G De Haan
Journal of Experimental Medicine 208 (13), 2691-2703, 2011
5082011
Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential
DG Kent, MR Copley, C Benz, S Wöhrer, BJ Dykstra, E Ma, J Cheyne, ...
Blood, The Journal of the American Society of Hematology 113 (25), 6342-6350, 2009
3932009
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
MB Bowie, DG Kent, B Dykstra, KD McKnight, L McCaffrey, PA Hoodless, ...
Proceedings of the National Academy of Sciences 104 (14), 5878-5882, 2007
3022007
Cellular barcoding tool for clonal analysis in the hematopoietic system
A Gerrits, B Dykstra, OJ Kalmykowa, K Klauke, E Verovskaya, ...
Blood, The Journal of the American Society of Hematology 115 (13), 2610-2618, 2010
2882010
The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets
HB Sieburg, RH Cho, B Dykstra, N Uchida, CJ Eaves, CE Muller-Sieburg
Blood 107 (6), 2311-2316, 2006
2852006
Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway
D Kent, M Copley, C Benz, B Dykstra, M Bowie, C Eaves
Clinical Cancer Research 14 (7), 1926-1930, 2008
2372008
High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal
B Dykstra, J Ramunas, D Kent, L McCaffrey, E Szumsky, L Kelly, K Farn, ...
Proceedings of the National Academy of Sciences 103 (21), 8185-8190, 2006
1662006
Different in vivo repopulating activities of purified hematopoietic stem cells before and after being stimulated to divide in vitro with the same kinetics
N Uchida, B Dykstra, KJ Lyons, FYK Leung, CJ Eaves
Experimental hematology 31 (12), 1338-1347, 2003
1502003
Hematopoietic stem cell aging and self-renewal
B Dykstra, G de Haan
Cell and tissue research 331 (1), 91-101, 2008
1322008
ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status
N Uchida, B Dykstra, K Lyons, F Leung, M Kristiansen, C Eaves
Blood 103 (12), 4487-4495, 2004
972004
Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells
DG Kent, BJ Dykstra, J Cheyne, E Ma, CJ Eaves
Blood, The Journal of the American Society of Hematology 112 (3), 560-567, 2008
802008
Distinct human α (1, 3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells
N Mondal, B Dykstra, J Lee, DJ Ashline, VN Reinhold, DJ Rossi, ...
Journal of Biological Chemistry 293 (19), 7300-7314, 2018
752018
Changes in the proliferative activity of human hematopoietic stem cells in NOD/SCID mice and enhancement of their transplantability after in vivo treatment with cell cycle …
J Cashman, B Dykstra, I Clark-Lewis, A Eaves, C Eaves
The Journal of experimental medicine 196 (9), 1141-1150, 2002
752002
Platelet bioreactor: accelerated evolution of design and manufacture
JN Thon, BJ Dykstra, LM Beaulieu
Platelets 28 (5), 472-477, 2017
642017
Characterization of mouse hematopoietic stem and progenitor cells
CL Miller, B Dykstra, CJ Eaves
Current Protocols in Immunology 80 (1), 22B. 2.1-22B. 2.31, 2008
522008
Glycoengineering of E-selectin ligands by intracellular versus extracellular fucosylation differentially affects osteotropism of human mesenchymal stem cells
B Dykstra, J Lee, LJ Mortensen, H Yu, ZL Wu, CP Lin, DJ Rossi, ...
Stem cells 34 (10), 2501-2511, 2016
492016
mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell–derived hematopoietic progenitors
J Lee, B Dykstra, JA Spencer, LL Kenney, DL Greiner, LD Shultz, ...
The Journal of clinical investigation 127 (6), 2433-2437, 2017
302017
Optimizing human Treg immunotherapy by Treg subset selection and E-selectin ligand expression
C Donnelly, B Dykstra, N Mondal, J Huang, BJ Kaskow, R Griffin, ...
Scientific Reports 8 (1), 420, 2018
252018
Combining transcriptional profiling and genetic linkage analysis to uncover gene networks operating in hematopoietic stem cells and their progeny
A Gerrits, B Dykstra, M Otten, L Bystrykh, G de Haan
Immunogenetics 60, 411-422, 2008
252008
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