Douglas Pires
Douglas Pires
School of Computing and Information Systems, The University of Melbourne
E-mail confirmado em unimelb.edu.au - Página inicial
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pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures
DEV Pires, TL Blundell, DB Ascher
Journal of medicinal chemistry 58 (9), 4066-4072, 2015
10862015
mCSM: predicting the effects of mutations in proteins using graph-based signatures
DEV Pires, DB Ascher, TL Blundell
Bioinformatics 30 (3), 335-342, 2014
5812014
DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach
DEV Pires, DB Ascher, TL Blundell
Nucleic acids research 42 (W1), W314-W319, 2014
4942014
DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
CHM Rodrigues, DEV Pires, DB Ascher
Nucleic acids research 46 (W1), W350-W355, 2018
3812018
mCSM-PPI2: predicting the effects of mutations on protein–protein interactions
CHM Rodrigues, Y Myung, DEV Pires, DB Ascher
Nucleic acids research 47 (W1), W338-W344, 2019
1232019
Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD
KA Andrews, DB Ascher, DEV Pires, DR Barnes, L Vialard, RT Casey, ...
Journal of medical genetics 55 (6), 384-394, 2018
1122018
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance
J Phelan, F Coll, R McNerney, DB Ascher, DEV Pires, N Furnham, ...
BMC medicine 14 (1), 1-13, 2016
962016
mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance
DEV Pires, TL Blundell, DB Ascher
Scientific reports 6 (1), 1-8, 2016
962016
Protein cutoff scanning: A comparative analysis of cutoff dependent and cutoff free methods for prospecting contacts in proteins
CH da Silveira, DEV Pires, RC Minardi, C Ribeiro, CJM Veloso, ...
Proteins: Structure, Function, and Bioinformatics 74 (3), 727-743, 2009
922009
CSM-lig: a web server for assessing and comparing protein–small molecule affinities
DEV Pires, DB Ascher
Nucleic acids research 44 (W1), W557-W561, 2016
822016
Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’in Italy
M Nemethova, J Radvanszky, L Kadasi, DB Ascher, DEV Pires, ...
European Journal of Human Genetics 24 (1), 66-72, 2016
812016
In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity
DEV Pires, J Chen, TL Blundell, DB Ascher
Scientific reports 6 (1), 1-11, 2016
742016
mCSM–NA: predicting the effects of mutations on protein–nucleic acids interactions
DEV Pires, DB Ascher
Nucleic acids research 45 (W1), W241-W246, 2017
712017
Germline mutations in the CDKN2B tumor suppressor gene predispose to renal cell carcinoma
M Jafri, NC Wake, DB Ascher, DEV Pires, D Gentle, MR Morris, ...
Cancer discovery 5 (7), 723-729, 2015
702015
Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes
DEV Pires, TL Blundell, DB Ascher
Nucleic acids research 43 (D1), D387-D391, 2015
702015
mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures
DEV Pires, DB Ascher
Nucleic acids research 44 (W1), W469-W473, 2016
692016
Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns
DEV Pires, RC de Melo-Minardi, MA dos Santos, CH da Silveira, ...
BMC Genomics 12 (Suppl 4), S12, 2011
622011
Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses
ACR Silvino, GL Costa, FCF Araújo, DB Ascher, DEV Pires, CJF Fontes, ...
PloS one 11 (7), e0160172, 2016
562016
A campaign-based characterization of spamming strategies
PH Calais, DEV Pires, DO Guedes, W Meira Jr, C Hoepers, KS Jessen
562008
aCSM: Noise-free graph-based signatures to large-scale receptor-based ligand prediction
DEV Pires, RC de Melo-Minardi, CH da Silveira, FF Campos, W Meira
Bioinformatics 29 (7), 855-861, 2013
462013
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