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Juan Mangas-Sanchez
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A reductive aminase from Aspergillus oryzae
GA Aleku, SP France, H Man, J Mangas-Sanchez, SL Montgomery, ...
Nature chemistry 9 (10), 961-969, 2017
3372017
Imine reductases (IREDs)
J Mangas-Sanchez, SP France, SL Montgomery, GA Aleku, H Man, ...
Current opinion in chemical biology 37, 19-25, 2017
2332017
NAD (P) H‐dependent dehydrogenases for the asymmetric reductive amination of ketones: Structure, mechanism, evolution and application
M Sharma, J Mangas‐Sanchez, NJ Turner, G Grogan
Advanced Synthesis & Catalysis 359 (12), 2011-2025, 2017
1212017
Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination
JR Marshall, P Yao, SL Montgomery, JD Finnigan, TW Thorpe, RB Palmer, ...
Nature chemistry 13 (2), 140-148, 2021
1162021
Direct alkylation of amines with primary and secondary alcohols through biocatalytic hydrogen borrowing
SL Montgomery, J Mangas‐Sanchez, MP Thompson, GA Aleku, ...
Angewandte Chemie 129 (35), 10627-10630, 2017
1122017
Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades
JI Ramsden, RS Heath, SR Derrington, SL Montgomery, ...
Journal of the American Chemical Society 141 (3), 1201-1206, 2019
1092019
Identification of novel bacterial members of the imine reductase enzyme family that perform reductive amination
SP France, RM Howard, J Steflik, NJ Weise, J Mangas‐Sanchez, ...
ChemCatChem 10 (3), 510-514, 2018
1002018
Chemoenzymatic synthesis of rivastigmine based on lipase-catalyzed processes
J Mangas-Sanchez, M Rodriguez-Mata, E Busto, V Gotor-Fernandez, ...
The Journal of Organic Chemistry 74 (15), 5304-5310, 2009
942009
A mechanism for reductive amination catalyzed by fungal reductive aminases
M Sharma, J Mangas-Sanchez, SP France, GA Aleku, SL Montgomery, ...
ACS Catalysis 8 (12), 11534-11541, 2018
912018
Asymmetric chemoenzymatic synthesis of miconazole and econazole enantiomers. The importance of chirality in their biological evaluation
J Mangas-Sánchez, E Busto, V Gotor-Fernández, F Malpartida, V Gotor
The Journal of organic chemistry 76 (7), 2115-2122, 2011
862011
A generic platform for the immobilisation of engineered biocatalysts
MP Thompson, SR Derrington, RS Heath, JL Porter, J Mangas-Sanchez, ...
Tetrahedron 75 (3), 327-334, 2019
842019
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
SP France, GA Aleku, M Sharma, J Mangas‐Sanchez, RM Howard, ...
Angewandte Chemie International Edition 56 (49), 15589-15593, 2017
782017
Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases
J Mangas-Sanchez, M Sharma, SC Cosgrove, JI Ramsden, JR Marshall, ...
Chemical science 11 (19), 5052-5057, 2020
612020
Straightforward synthesis of enantiopure 2, 3-dihydrobenzofurans by a sequential stereoselective biotransformation and chemical intramolecular cyclization
J Mangas-Sanchez, E Busto, V Gotor-Fernandez, V Gotor
Organic Letters 12 (15), 3498-3501, 2010
612010
Enantioselective synthesis of chiral vicinal amino alcohols using amine dehydrogenases
FF Chen, SC Cosgrove, WR Birmingham, J Mangas-Sanchez, J Citoler, ...
ACS Catalysis 9 (12), 11813-11818, 2019
602019
Phenolic and antioxidant composition of cider
AP Lobo, YD García, JM Sanchez, RR Madrera, BS Valles
Journal of food composition and analysis 22 (7-8), 644-648, 2009
592009
Kinetic resolution and deracemization of racemic amines using a reductive aminase
GA Aleku, J Mangas‐Sanchez, J Citoler, SP France, SL Montgomery, ...
ChemCatChem 10 (3), 515-519, 2018
562018
One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles
TW Thorpe, SP France, S Hussain, JR Marshall, W Zawodny, ...
Journal of the American Chemical Society 141 (49), 19208-19213, 2019
542019
Highly efficient enzymatic biodiesel production promoted by particle-induced emulsification
J Mangas-Sánchez, P Adlercreutz
Biotechnology for biofuels 8, 1-8, 2015
522015
Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships
SL Montgomery, A Pushpanath, RS Heath, JR Marshall, U Klemstein, ...
Science advances 6 (21), eaay9320, 2020
492020
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