A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. HC Cheng, BE Kemp, RB Pearson, AJ Smith, L Misconi, SM Van Patten, ... Journal of Biological Chemistry 261 (3), 989-992, 1986 | 653 | 1986 |
Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable … DB Glass, HC Cheng, L Mende-Mueller, J Reed, DA Walsh Journal of Biological Chemistry 264 (15), 8802-8810, 1989 | 329 | 1989 |
Regulation and function of protein kinases and phosphatases HC Cheng, RZ Qi, H Paudel, HJ Zhu Enzyme research 2011, 2011 | 207 | 2011 |
A synthetic peptide derived from p34cdc2 is a specific and efficient substrate of src-family tyrosine kinases. HC Cheng, H Nishio, O Hatase, S Ralph, JH Wang Journal of Biological Chemistry 267 (13), 9248-9256, 1992 | 182 | 1992 |
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1 CH Sim, DSS Lio, SS Mok, CL Masters, AF Hill, JG Culvenor, HC Cheng Human molecular genetics 15 (21), 3251-3262, 2006 | 168 | 2006 |
Phosphorylation of Avena phytochrome in vitro as a probe of light-induced conformational changes. YS Wong, HC Cheng, DA Walsh, JC Lagarias Journal of Biological Chemistry 261 (26), 12089-12097, 1986 | 152 | 1986 |
Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative … C Egan, A Pang, D Durda, HC Cheng, JH Wang, DJ Fujita Oncogene 18 (5), 1227-1237, 1999 | 146 | 1999 |
C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)—endogenous negative regulators of Src-family protein kinases: Mini Review YP Chong, TD Mulhern, HC Cheng Growth factors 23 (3), 233-244, 2005 | 145 | 2005 |
Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases YP Chong, KK Ia, TD Mulhern, HC Cheng Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1754 (1-2), 210-220, 2005 | 143 | 2005 |
An active twenty-amino-acid-residue peptide derived from the inhibitor protein of the cyclic AMP-dependent protein kinase HC Cheng, SM van Patten, AJ Smith, DA Walsh Biochemical Journal 231 (3), 655-661, 1985 | 139 | 1985 |
Differential and common recognition of the catalytic sites of the cGMP-dependent and cAMP-dependent protein kinases by inhibitory peptides derived from the heat-stable … DB Glass, HC Cheng, BE Kemp, DA Walsh Journal of Biological Chemistry 261 (26), 12166-12171, 1986 | 132 | 1986 |
Biochemical aspects of the neuroprotective mechanism of PTEN‐induced kinase‐1 (PINK1) RD Mills, CH Sim, SS Mok, TD Mulhern, JG Culvenor, HC Cheng Journal of neurochemistry 105 (1), 18-33, 2008 | 129 | 2008 |
Phospholamban regulation of cardiac sarcoplasmic reticulum (Ca (2+)-Mg2+)-ATPase. Mechanism of regulation and site of monoclonal antibody interaction GL Morris, HC Cheng, J Colyer, JH Wang Journal of Biological Chemistry 266 (17), 11270-11275, 1991 | 107 | 1991 |
Autophosphorylation Induces Autoactivation and a Decrease in the Src Homology 2 Domain Accessibility of the Lyn Protein Kinase (∗) N Sotirellis, TM Johnson, ML Hibbs, IJ Stanley, E Stanley, AR Dunn, ... Journal of Biological Chemistry 270 (50), 29773-29780, 1995 | 75 | 1995 |
A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity YP Chong, TD Mulhern, HJ Zhu, DJ Fujita, JD Bjorge, JP Tantiongco, ... Journal of Biological Chemistry 279 (20), 20752-20766, 2004 | 72 | 2004 |
[16] Peptide inhibitors of CAMP-dependent protein kinase BE Kemp, HC Cheng, DA Walsh Methods in enzymology 159, 173-183, 1988 | 65 | 1988 |
Characterization of Two Activated Mutants of Human pp60c-src That Escape c-Src Kinase Regulation by Distinct Mechanisms (∗) JD Bjorge, C Bellagamba, HC Cheng, A Tanaka, JH Wang, DJ Fujita Journal of Biological Chemistry 270 (41), 24222-24228, 1995 | 62 | 1995 |
C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases YP Chong, AS Chan, KC Chan, NA Williamson, EC Lerner, TE Smithgall, ... Journal of biological chemistry 281 (44), 32988-32999, 2006 | 58 | 2006 |
A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity MI Hossain, CL Roulston, MA Kamaruddin, PWY Chu, DCH Ng, ... Journal of Biological Chemistry 288 (14), 9696-9709, 2013 | 56 | 2013 |
Structural basis of specific and efficient phosphorylation of peptides derived from p34cdc2 by a pp60src-related protein tyrosine kinase. HC Cheng, CM Litwin, DM Hwang, JH Wang Journal of Biological Chemistry 266 (27), 17919-17925, 1991 | 52 | 1991 |