| Heat shock proteins as immunomodulants T Zininga, L Ramatsui, A Shonhai Molecules 23 (11), 2846, 2018 | 302 | 2018 |
| Plasmodium falciparum Hop (PfHop) interacts with the Hsp70 chaperone in a nucleotide-dependent fashion and exhibits ligand selectivity T Zininga, S Makumire, GW Gitau, JM Njunge, OJ Pooe, H Klimek, ... PLoS One 10 (8), e0135326, 2015 | 53 | 2015 |
| Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion T Zininga, I Achilonu, H Hoppe, E Prinsloo, HW Dirr, A Shonhai Cell Stress and Chaperones 21 (3), 499-513, 2016 | 47 | 2016 |
| Overexpression, purification and characterisation of the Plasmodium falciparum Hsp70-z (PfHsp70-z) protein T Zininga, I Achilonu, H Hoppe, E Prinsloo, HW Dirr, A Shonhai PLoS One 10 (6), e0129445, 2015 | 42 | 2015 |
| Structural and biochemical characterization of Plasmodium falciparum Hsp70‐x reveals functional versatility of its C‐terminal EEVN motif B Mabate, T Zininga, L Ramatsui, S Makumire, I Achilonu, HW Dirr, ... Proteins: Structure, Function, and Bioinformatics 86 (11), 1189-1201, 2018 | 40 | 2018 |
| Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70 T Zininga, OJ Pooe, PB Makhado, L Ramatsui, E Prinsloo, I Achilonu, ... Cell Stress and Chaperones 22 (5), 707-715, 2017 | 40 | 2017 |
| (−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional … T Zininga, L Ramatsui, PB Makhado, S Makumire, I Achilinou, H Hoppe, ... Molecules 22 (12), 2139, 2017 | 36 | 2017 |
| Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors F Kayamba, T Malimabe, IK Ademola, OJ Pooe, ND Kushwaha, ... European Journal of Medicinal Chemistry 217, 113330, 2021 | 35 | 2021 |
| Small molecule inhibitors targeting the heat shock protein system of human obligate protozoan parasites T Zininga, A Shonhai International journal of molecular sciences 20 (23), 5930, 2019 | 35 | 2019 |
| Comparative structure-function features of Hsp70s of Plasmodium falciparum and human origins G Chakafana, T Zininga, A Shonhai Biophysical reviews 11 (4), 591-602, 2019 | 32 | 2019 |
| The link that binds: the linker of Hsp70 as a helm of the protein’s function G Chakafana, T Zininga, A Shonhai Biomolecules 9 (10), 543, 2019 | 26 | 2019 |
| Comparative in vitro cytotoxic, anti-inflammatory and anti-microbiological activities of two indigenous Venda medicinal plants MT Sigidi, CP Anokwuru, T Zininga, MP Tshisikhawe, A Shonhai, ... Translational Medicine Communications 1, 1-7, 2016 | 26 | 2016 |
| Comparative Characterization of Plasmodium falciparum Hsp70-1 Relative to E. coli DnaK Reveals the Functional Specificity of the Parasite Chaperone CM Lebepe, PR Matambanadzo, XH Makhoba, I Achilonu, T Zininga, ... Biomolecules 10 (6), 856, 2020 | 24 | 2020 |
| Are Heat Shock Proteins Druggable Candidates? AS Tawanda Zininga American Journal of Biochemistry and Biotechnology 10 (4), 208-210, 2014 | 24 | 2014 |
| Extracts Obtained from Pterocarpus angolensis DC and Ziziphus mucronata Exhibit Antiplasmodial Activity and Inhibit Heat Shock Protein 70 (Hsp70) Function T Zininga, CP Anokwuru, MT Sigidi, MP Tshisikhawe, IID Ramaite, ... Molecules 22 (8), 1224, 2017 | 20 | 2017 |
| Use of a chimeric Hsp70 to enhance the quality of recombinant Plasmodium falciparum S-adenosylmethionine decarboxylase protein produced in Escherichia coli XH Makhoba, A Burger, D Coertzen, T Zininga, LM Birkholtz, A Shonhai PLoS One 11 (3), e0152626, 2016 | 20 | 2016 |
| Inhibitors of the Plasmodium falciparum Hsp90 towards Selective Antimalarial Drug Design: The Past, Present and Future ML Stofberg, C Caillet, M de Villiers, T Zininga Cells 10 (11), 2849, 2021 | 15 | 2021 |
| Mutation of GGMP Repeat Segments of Plasmodium falciparum Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding S Makumire, TH Dongola, G Chakafana, L Tshikonwane, CT Chauke, ... International Journal of Molecular Sciences 22 (4), 2226, 2021 | 15 | 2021 |
| Phenolic contents, antioxidant activity and spectroscopic characteristics of Pterocarpus angolensis DC. stem bark fractions. CP Anokwuru, MT Sigidi, T Zininga, MP Tshisikhawe, A Shonhai, ... Indian Journal of Traditional Knowledge 16 (3), 400-406, 2017 | 14 | 2017 |
| Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected … S Makumire, T Zininga, J Vahokoski, I Kursula, A Shonhai PLoS One 15 (4), e0226657, 2020 | 12 | 2020 |
