|Heparan sulfate and heparin interactions with proteins|
MCZ Meneghetti, AJ Hughes, TR Rudd, HB Nader, AK Powell, EA Yates, ...
Journal of the Royal Society Interface 12 (110), 20150589, 2015
|N-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding|
L Duchesne, B Tissot, TR Rudd, A Dell, DG Fernig
Journal of Biological Chemistry 281 (37), 27178-27189, 2006
|Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives|
TR Rudd, SE Guimond, MA Skidmore, L Duchesne, M Guerrini, G Torri, ...
Glycobiology 17 (9), 983-993, 2007
|Real-time monitoring of the development and stability of biofilms of Streptococcus mutans using the quartz crystal microbalance with dissipation monitoring|
AL Schofield, TR Rudd, DS Martin, DG Fernig, C Edwards
Biosensors and Bioelectronics 23 (3), 407-413, 2007
|Diversification of the structural determinants of fibroblast growth factor-heparin interactions implications for binding specificity|
R Xu, A Ori, TR Rudd, KA Uniewicz, YA Ahmed, SE Guimond, ...
Journal of Biological Chemistry 287 (47), 40061-40073, 2012
|Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra|
TR Rudd, MA Skidmore, SE Guimond, C Cosentino, G Torri, DG Fernig, ...
Glycobiology 19 (1), 52-67, 2009
|The conformation and structure of GAGs: recent progress and perspectives|
TR Rudd, MA Skidmore, M Guerrini, M Hricovini, AK Powell, G Siligardi, ...
Current opinion in structural biology 20 (5), 567-574, 2010
|An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence|
M Guerrini, S Elli, P Mourier, TR Rudd, D Gaudesi, B Casu, C Boudier, ...
Biochemical Journal 449 (2), 343-351, 2013
|Site-specific interactions of copper (II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques|
TR Rudd, MA Skidmore, SE Guimond, M Guerrini, C Cosentino, R Edge, ...
Carbohydrate research 343 (12), 2184-2193, 2008
|CDApps: integrated software for experimental planning and data processing at beamline B23, Diamond Light Source|
R Hussain, K Benning, T Javorfi, E Longo, TR Rudd, B Pulford, G Siligardi
Journal of synchrotron radiation 22 (2), 465-468, 2015
|Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships|
TR Rudd, KA Uniewicz, A Ori, SE Guimond, MA Skidmore, D Gaudesi, ...
Organic & biomolecular chemistry 8 (23), 5390-5397, 2010
|The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation|
MA Skidmore, SE Guimond, TR Rudd, DG Fernig, JE Turnbull, EA Yates
Connective tissue research 49 (3-4), 140-144, 2008
|Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network|
R Xu, TR Rudd, AJ Hughes, G Siligardi, DG Fernig, EA Yates
The FEBS journal 280 (10), 2260-2270, 2013
|Protein–GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes|
EA Yates, CJ Terry, C Rees, TR Rudd, L Duchesne, MA Skidmore, R Levy, ...
Biochemical Society Transactions 34 (3), 427-430, 2006
|A highly efficient tree structure for the biosynthesis of heparan sulfate accounts for the commonly observed disaccharides and suggests a mechanism for domain synthesis|
TR Rudd, EA Yates
Molecular BioSystems 8 (5), 1499-1506, 2012
|Human (α2→ 6) and avian (α2→ 3) sialylated receptors of influenza A virus show distinct conformations and dynamics in solution|
GL Sassaki, S Elli, TR Rudd, E Macchi, EA Yates, A Naggi, Z Shriver, ...
Biochemistry 52 (41), 7217-7230, 2013
|A new approach for heparin standardization: Combination of scanning UV spectroscopy, nuclear magnetic resonance and principal component analysis|
MA Lima, TR Rudd, EHC de Farias, LF Ebner, TF Gesteira, LM de Souza, ...
PLoS One 6 (1), e15970, 2011
|Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin.|
C Mycroft-West, D Su, I Pagani, T Rudd, S Elli, S Guimond, G Miller, ...
|Differentiation of generic enoxaparins marketed in the United States by employing NMR and multivariate analysis|
M Guerrini, TR Rudd, L Mauri, E Macchi, J Fareed, EA Yates, A Naggi, ...
Analytical chemistry 87 (16), 8275-8283, 2015
|New applications of heparin and other glycosaminoglycans|
M Lima, T Rudd, E Yates
Molecules 22 (5), 749, 2017