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Akram Alian, Ph.D.
Akram Alian, Ph.D.
University of Utah Medical School
E-mail confirmado em biochem.utah.edu
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Ano
Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern
Y Ashhab, A Alian, A Polliack, A Panet, DB Yehuda
FEBS letters 495 (1-2), 56-60, 2001
5922001
Pyrrolidine Carboxamides as a Novel Class of Inhibitors of Enoyl Acyl Carrier Protein Reductase from Mycobacterium tuberculosis
X He, A Alian, R Stroud, PR Ortiz de Montellano
Journal of medicinal chemistry 49 (21), 6308-6323, 2006
2632006
Genotypic difference in salinity and water stress tolerance of fresh market tomato cultivars
A Alian, A Altman, B Heuer
Plant science 152 (1), 59-65, 2000
2422000
Fabs enable single particle cryoEM studies of small proteins
S Wu, A Avila-Sakar, JM Kim, DS Booth, CH Greenberg, A Rossi, M Liao, ...
Structure 20 (4), 582-592, 2012
1742012
Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides
X He, A Alian, PRO De Montellano
Bioorganic & medicinal chemistry 15 (21), 6649-6658, 2007
1552007
Human peripheral blood eosinophils induce angiogenesis
I Puxeddu, A Alian, AM Piliponsky, D Ribatti, A Panet, F Levi-Schaffer
The international journal of biochemistry & cell biology 37 (3), 628-636, 2005
1502005
WW domain-containing proteins: retrospectives and the future
Z Salah, A Alian, RI Aqeilan
Front Biosci 17 (1), 331-348, 2012
1292012
Structure of a TrmA–RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases
A Alian, TT Lee, SL Griner, RM Stroud, J Finer-Moore
Proceedings of the National Academy of Sciences 105 (19), 6876-6881, 2008
962008
Avian hemangioma retrovirus induces cell proliferation via the envelope (env) gene
A Alian, D Sela-Donenfeld, A Panet, A Eldor
Virology 276 (1), 161-168, 2000
562000
Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs
A Alian, SL Griner, V Chiang, M Tsiang, G Jones, G Birkus, R Geleziunas, ...
Proceedings of the National Academy of Sciences 106 (20), 8192-8197, 2009
472009
Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450cam by an L244A mutation
A Verras, A Alian, PRO Montellano
Protein Engineering, Design and Selection 19 (11), 491-496, 2006
372006
Crystal structure of an RluF–RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome
A Alian, A DeGiovanni, SL Griner, JS Finer-Moore, RM Stroud
Journal of molecular biology 388 (4), 785-800, 2009
312009
The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs
N Czudnochowski, GW Ashley, DV Santi, A Alian, J Finer-Moore, ...
Nucleic acids research 42 (3), 2037-2048, 2014
292014
Zinc enhancement of cytidine deaminase activity highlights a potential allosteric role of loop-3 in regulating APOBEC3 enzymes
A Marx, M Galilee, A Alian
Scientific reports 5 (1), 18191, 2015
212015
The first crystal structure of a dTTP-bound deoxycytidylate deaminase validates and details the allosteric-inhibitor binding site
A Marx, A Alian
Journal of Biological Chemistry 290 (1), 682-690, 2015
202015
Ortiz de Montellano PR Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
X He, A Alian, R Stroud
J. Med. Chem 49 (21), 6308-6323, 2006
172006
Viral mediated gene transfer to sprouting blood vessels during angiogenesis
A Alian, A Eldor, H Falk, A Panet
Journal of virological methods 105 (1), 1-11, 2002
162002
The structure of FIV reverse transcriptase and its implications for non-nucleoside inhibitor resistance
M Galilee, A Alian
PLoS pathogens 14 (1), e1006849, 2018
132018
Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release
L Rheinemann, T Thompson, G Mercenne, EL Paine, FC Peterson, ...
Journal of Biological Chemistry 297 (2), 2021
102021
The road less traveled: HIV's use of alternative routes through cellular pathways
A Marx, A Alian
Journal of virology 89 (10), 5204-5212, 2015
102015
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Artigos 1–20