Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease EJ van Beers, MCL Schaap, RJ Berckmans, R Nieuwland, A Sturk, ... haematologica 94 (11), 1513, 2009 | 318 | 2009 |
Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study RF Grace, P Bianchi, EJ van Beers, SW Eber, B Glader, HM Yaish, ... Blood, The Journal of the American Society of Hematology 131 (20), 2183-2192, 2018 | 157 | 2018 |
Patient‐controlled analgesia versus continuous infusion of morphine during vaso‐occlusive crisis in sickle cell disease, a randomized controlled trial EJ van Beers, CFJ van Tuijn, PT Nieuwkerk, PW Friederich, JH Vranken, ... American journal of hematology 82 (11), 955-960, 2007 | 128 | 2007 |
Safety and efficacy of mitapivat in pyruvate kinase deficiency RF Grace, C Rose, DM Layton, F Galactéros, W Barcellini, DH Morton, ... New England Journal of Medicine 381 (10), 933-944, 2019 | 123 | 2019 |
Iron, inflammation, and early death in adults with sickle cell disease EJ Van Beers, Y Yang, N Raghavachari, X Tian, DT Allen, JS Nichols, ... Circulation research 116 (2), 298-306, 2015 | 99 | 2015 |
Cerebrovascular reserve capacity is impaired in patients with sickle cell disease E Nur, YS Kim, J Truijen, EJ van Beers, SCAT Davis, DP Brandjes, ... Blood, The Journal of the American Society of Hematology 114 (16), 3473-3478, 2009 | 85 | 2009 |
Sickle cell disease: clinical presentation and management of a global health challenge ME Houwing, PJ De Pagter, EJ Van Beers, BJ Biemond, E Rettenbacher, ... Blood reviews 37, 100580, 2019 | 81 | 2019 |
Imaging flow cytometry for automated detection of hypoxia‐induced erythrocyte shape change in sickle cell disease EJ Van Beers, L Samsel, L Mendelsohn, R Saiyed, KY Fertrin, ... American journal of hematology 89 (6), 598-603, 2014 | 77 | 2014 |
Addressing the diagnostic gaps in pyruvate kinase deficiency: consensus recommendations on the diagnosis of pyruvate kinase deficiency P Bianchi, E Fermo, B Glader, H Kanno, A Agarwal, W Barcellini, S Eber, ... American journal of hematology 94 (1), 149-161, 2019 | 71 | 2019 |
Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients MAE Rab, BA van Oirschot, J Bos, TH Merkx, ACW van Wesel, ... American journal of hematology 94 (5), 575-584, 2019 | 66 | 2019 |
Sickle cell disease-related organ damage occurs irrespective of pain rate: implications for clinical practice EJ van Beers, CFJ van Tuijn, MR Mac Gillavry, A van der Giessen, ... haematologica 93 (5), 757-760, 2008 | 63 | 2008 |
Venous thromboembolism and prothrombotic parameters in Klippel-Trenaunay syndrome CE Oduber, EJ Van Beers, P Bresser, CM Van der Horst, JC Meijers, ... Neth J Med 71 (5), 246-252, 2013 | 58 | 2013 |
AG-348 (mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and adenosine triphosphate levels over a broad … MAE Rab, BA Van Oirschot, PA Kosinski, J Hixon, K Johnson, ... Haematologica 106 (1), 238, 2021 | 55 | 2021 |
Genotype‐phenotype correlation and molecular heterogeneity in pyruvate kinase deficiency P Bianchi, E Fermo, K Lezon‐Geyda, EJ van Beers, HD Morton, ... American journal of hematology 95 (5), 472-482, 2020 | 54 | 2020 |
The complexity of genotype-phenotype correlations in hereditary spherocytosis: a cohort of 95 patients: genotype-phenotype correlation in hereditary spherocytosis A van Vuren, B van der Zwaag, R Huisjes, N Lak, M Bierings, E Gerritsen, ... Hemasphere 3 (4), e276, 2019 | 54 | 2019 |
Mitapivat versus placebo for pyruvate kinase deficiency H Al-Samkari, F Galactéros, A Glenthøj, JA Rothman, O Andres, RF Grace, ... New England Journal of Medicine 386 (15), 1432-1442, 2022 | 53 | 2022 |
Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study EJ Van Beers, S Van Straaten, DH Morton, W Barcellini, SW Eber, ... Haematologica 104 (2), e51, 2019 | 53 | 2019 |
Worldwide study of hematopoietic allogeneic stem cell transplantation in pyruvate kinase deficiency S Van Straaten, M Bierings, P Bianchi, K Akiyoshi, H Kanno, IB Serra, ... Haematologica 103 (2), e82, 2018 | 53 | 2018 |
No association of the hypercoagulable state with sickle cell disease related pulmonary hypertension EJ Van Beers, HMH Spronk, H ten Cate, AJ Duits, DPM Brandjes, ... Haematologica 93 (5), e42-e44, 2008 | 49 | 2008 |
Pain rate and social circumstances rather than cumulative organ damage determine the quality of life in adults with sickle cell disease. CFJ van Tuijn, EJ Van Beers, JJB Schnog, BJ Biemond American journal of hematology 85 (7), 532, 2010 | 48 | 2010 |