| Folic acid prevents depressive-like behavior and hippocampal antioxidant imbalance induced by restraint stress in mice J Budni, AD Zomkowski, D Engel, DB Santos, AA dos Santos, M Moretti, ... Experimental neurology 240, 112-121, 2013 | 112 | 2013 |
| Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test ADE Zomkowski, D Engel, NH Gabilan, ALS Rodrigues European Neuropsychopharmacology 20 (11), 793-801, 2010 | 105 | 2010 |
| β-Caryophyllene protects the C6 glioma cells against glutamate-induced excitotoxicity through the Nrf2 pathway LC Assis, MR Straliotto, D Engel, MA Hort, RC Dutra, AF De Bem Neuroscience 279, 220-231, 2014 | 90 | 2014 |
| Hippocampal function is impaired by a short-term high-fat diet in mice: Increased blood–brain barrier permeability and neuroinflammation as triggering events GC de Paula, HS Brunetta, DF Engel, JM Gaspar, LA Velloso, D Engblom, ... Frontiers in neuroscience 15, 734158, 2021 | 72 | 2021 |
| Chronic administration of duloxetine and mirtazapine downregulates proapoptotic proteins and upregulates neurotrophin gene expression in the hippocampus and cerebral cortex of mice D Engel, ADE Zomkowski, V Lieberknecht, AL Rodrigues, NH Gabilan Journal of psychiatric research 47 (6), 802-808, 2013 | 58 | 2013 |
| Hypercholesterolemia induces short-term spatial memory impairments in mice: up-regulation of acetylcholinesterase activity as an early and causal event? ELG Moreira, J de Oliveira, DF Engel, R Walz, AF de Bem, M Farina, ... Journal of neural transmission 121, 415-426, 2014 | 57 | 2014 |
| Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system RL Quispe, ML Jaramillo, LS Galant, D Engel, AL Dafre, JBT da Rocha, ... Redox biology 20, 118-129, 2019 | 52 | 2019 |
| High cholesterol diet exacerbates blood-brain barrier disruption in LDLr–/–mice: impact on cognitive function J de Oliveira, DF Engel, GC De Paula, DB Dos Santos, JB Lopes, ... Journal of Alzheimer's Disease 78 (1), 97-115, 2020 | 51 | 2020 |
| The role of the NMDA receptors and L-arginine–nitric oxide–cyclic guanosine monophosphate pathway in the antidepressant-like effect of duloxetine in the forced swimming test ADE Zomkowski, D Engel, MP Cunha, NH Gabilan, ALS Rodrigues Pharmacology Biochemistry and Behavior 103 (2), 408-417, 2012 | 46 | 2012 |
| The bile acid TUDCA improves glucose metabolism in streptozotocin-induced Alzheimer's disease mice model L Zangerolamo, JF Vettorazzi, C Solon, GA Bronczek, DF Engel, ... Molecular and Cellular Endocrinology 521, 111116, 2021 | 44 | 2021 |
| Succinobucol, a lipid-lowering drug, protects against 3-nitropropionic acid-induced mitochondrial dysfunction and oxidative stress in SH-SY5Y cells via upregulation of … D Colle, DB Santos, JM Hartwig, M Godoi, DF Engel, AF de Bem, ... Molecular neurobiology 53, 1280-1295, 2016 | 43 | 2016 |
| Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis VC Bobbo, DF Engel, CP Jara, NF Mendes, R Haddad-Tovolli, TP Prado, ... Journal of neuroinflammation 18, 1-17, 2021 | 36 | 2021 |
| Is there an association between hypercholesterolemia and depression? Behavioral evidence from the LDLr−/− mouse experimental model DF Engel, J de Oliveira, JB Lopes, DB Santos, ELG Moreira, M Farina, ... Behavioural brain research 311, 31-38, 2016 | 35 | 2016 |
| Brain-defective insulin signaling is associated to late cognitive impairment in post-septic mice FS Neves, PT Marques, F Barros‑Aragão, JB Nunes, AM Venancio, ... Molecular Neurobiology 55, 435-444, 2018 | 34 | 2018 |
| Interleukin-17 acts in the hypothalamus reducing food intake G Nogueira, C Solon, RS Carraro, DF Engel, AF Ramalho, ... Brain, behavior, and immunity 87, 272-285, 2020 | 32 | 2020 |
| Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: A role for the LDL receptor and cholesterol metabolism in adult neural precursor cells DF Engel, AN Grzyb, J de Oliveira, A Pötzsch, TL Walker, PS Brocardo, ... Molecular Metabolism 30, 1-15, 2019 | 29 | 2019 |
| Duloxetine protects human neuroblastoma cells from oxidative stress-induced cell death through Akt/Nrf-2/HO-1 pathway DF Engel, J de Oliveira, V Lieberknecht, ALS Rodrigues, AF de Bem, ... Neurochemical research 43, 387-396, 2018 | 25 | 2018 |
| LDL receptor deficiency does not alter brain amyloid-β levels but causes an exacerbation of apoptosis J de Oliveira, DF Engel, GC de Paula, HM Melo, SC Lopes, CT Ribeiro, ... Journal of Alzheimer's Disease 73 (2), 585-596, 2020 | 21 | 2020 |
| Glutamic acid promotes hair growth in mice CP Jara, B de Andrade Berti, NF Mendes, DF Engel, AM Zanesco, ... Scientific reports 11 (1), 15453, 2021 | 18 | 2021 |
| Activation of GPR40 induces hypothalamic neurogenesis through p38-and BDNF-dependent mechanisms DF Engel, VCD Bobbo, CS Solon, GA Nogueira, A Moura-Assis, ... Scientific reports 10 (1), 11047, 2020 | 17 | 2020 |
